| Full name: D-box binding PAR bZIP transcription factor | Alias Symbol: DABP | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 1628 | HGNC ID: HGNC:2697 | Ensembl Gene: ENSG00000105516 | OMIM ID: 124097 |
| Drug and gene relationship at DGIdb | |||
Expression of DBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DBP | 1628 | 209782_s_at | 0.4160 | 0.5125 | |
| GSE20347 | DBP | 1628 | 209783_at | -0.0166 | 0.8854 | |
| GSE23400 | DBP | 1628 | 209782_s_at | -0.2178 | 0.0000 | |
| GSE26886 | DBP | 1628 | 209782_s_at | -0.7306 | 0.0626 | |
| GSE29001 | DBP | 1628 | 209783_at | 0.0064 | 0.9760 | |
| GSE38129 | DBP | 1628 | 209782_s_at | -0.1857 | 0.2795 | |
| GSE45670 | DBP | 1628 | 209782_s_at | -0.4372 | 0.0829 | |
| GSE53622 | DBP | 1628 | 80948 | -0.7560 | 0.0000 | |
| GSE53624 | DBP | 1628 | 80948 | -0.7157 | 0.0000 | |
| GSE63941 | DBP | 1628 | 209782_s_at | 1.5307 | 0.0447 | |
| GSE77861 | DBP | 1628 | 209782_s_at | -0.2789 | 0.6741 | |
| GSE97050 | DBP | 1628 | A_23_P130753 | -0.3557 | 0.4630 | |
| SRP007169 | DBP | 1628 | RNAseq | -1.7548 | 0.0012 | |
| SRP008496 | DBP | 1628 | RNAseq | -2.0831 | 0.0000 | |
| SRP064894 | DBP | 1628 | RNAseq | -0.1957 | 0.5816 | |
| SRP133303 | DBP | 1628 | RNAseq | -0.5789 | 0.0077 | |
| SRP159526 | DBP | 1628 | RNAseq | -0.2376 | 0.5055 | |
| SRP193095 | DBP | 1628 | RNAseq | -0.7474 | 0.0005 | |
| SRP219564 | DBP | 1628 | RNAseq | -0.6448 | 0.1953 | |
| TCGA | DBP | 1628 | RNAseq | 0.0509 | 0.6176 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by DBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DBP | 1628 | 4 | 4 | 22 | |
| GSE20123 | DBP | 1628 | 4 | 3 | 23 | |
| GSE43470 | DBP | 1628 | 4 | 10 | 29 | |
| GSE46452 | DBP | 1628 | 45 | 1 | 13 | |
| GSE47630 | DBP | 1628 | 8 | 7 | 25 | |
| GSE54993 | DBP | 1628 | 17 | 4 | 49 | |
| GSE54994 | DBP | 1628 | 4 | 14 | 35 | |
| GSE60625 | DBP | 1628 | 9 | 0 | 2 | |
| GSE74703 | DBP | 1628 | 4 | 7 | 25 | |
| GSE74704 | DBP | 1628 | 4 | 1 | 15 | |
| TCGA | DBP | 1628 | 14 | 18 | 64 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of DBP:
Generating mutation plots.
Highly correlated genes for DBP:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DBP | TBC1D25 | 0.727507 | 3 | 0 | 3 |
| DBP | MAP1S | 0.723115 | 3 | 0 | 3 |
| DBP | INSRR | 0.68904 | 3 | 0 | 3 |
| DBP | PRKACA | 0.681855 | 3 | 0 | 3 |
| DBP | TIAM2 | 0.671059 | 3 | 0 | 3 |
| DBP | POLDIP3 | 0.669101 | 3 | 0 | 3 |
| DBP | LHX3 | 0.666246 | 4 | 0 | 3 |
| DBP | SLAIN1 | 0.657181 | 4 | 0 | 3 |
| DBP | ZNF740 | 0.655573 | 3 | 0 | 3 |
| DBP | TSNARE1 | 0.653298 | 3 | 0 | 3 |
| DBP | CASKIN2 | 0.652565 | 3 | 0 | 3 |
| DBP | SLFNL1 | 0.6501 | 3 | 0 | 3 |
| DBP | KRTAP5-8 | 0.648882 | 4 | 0 | 3 |
| DBP | DBH | 0.648287 | 4 | 0 | 4 |
| DBP | HADH | 0.645625 | 4 | 0 | 3 |
| DBP | XAB2 | 0.643266 | 3 | 0 | 3 |
| DBP | SLC10A2 | 0.638762 | 3 | 0 | 3 |
| DBP | KRT84 | 0.63627 | 4 | 0 | 3 |
| DBP | TAB1 | 0.635299 | 5 | 0 | 3 |
| DBP | RPL38 | 0.634928 | 3 | 0 | 3 |
For details and further investigation, click here
