| Full name: general transcription factor IIE subunit 1 | Alias Symbol: TFIIE-A|FE | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 2960 | HGNC ID: HGNC:4650 | Ensembl Gene: ENSG00000153767 | OMIM ID: 189962 |
| Drug and gene relationship at DGIdb | |||
Expression of GTF2E1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2E1 | 2960 | 205930_at | 0.8391 | 0.0271 | |
| GSE20347 | GTF2E1 | 2960 | 205930_at | 0.8838 | 0.0000 | |
| GSE23400 | GTF2E1 | 2960 | 205930_at | 0.7428 | 0.0000 | |
| GSE26886 | GTF2E1 | 2960 | 205930_at | 0.2103 | 0.3754 | |
| GSE29001 | GTF2E1 | 2960 | 205930_at | 0.8767 | 0.0000 | |
| GSE38129 | GTF2E1 | 2960 | 205930_at | 0.8624 | 0.0000 | |
| GSE45670 | GTF2E1 | 2960 | 205930_at | 0.8741 | 0.0000 | |
| GSE53622 | GTF2E1 | 2960 | 8979 | 0.6456 | 0.0000 | |
| GSE53624 | GTF2E1 | 2960 | 8979 | 0.9047 | 0.0000 | |
| GSE63941 | GTF2E1 | 2960 | 205930_at | 0.0686 | 0.8933 | |
| GSE77861 | GTF2E1 | 2960 | 205930_at | 0.7746 | 0.0721 | |
| GSE97050 | GTF2E1 | 2960 | A_23_P211748 | 0.7042 | 0.0700 | |
| SRP007169 | GTF2E1 | 2960 | RNAseq | 0.7278 | 0.0520 | |
| SRP008496 | GTF2E1 | 2960 | RNAseq | 0.8387 | 0.0013 | |
| SRP064894 | GTF2E1 | 2960 | RNAseq | 0.8969 | 0.0000 | |
| SRP133303 | GTF2E1 | 2960 | RNAseq | 0.8194 | 0.0000 | |
| SRP159526 | GTF2E1 | 2960 | RNAseq | 0.5344 | 0.0553 | |
| SRP193095 | GTF2E1 | 2960 | RNAseq | 0.6434 | 0.0000 | |
| SRP219564 | GTF2E1 | 2960 | RNAseq | 0.6117 | 0.0063 | |
| TCGA | GTF2E1 | 2960 | RNAseq | 0.2655 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2E1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2E1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2E1 | 2960 | 18 | 0 | 12 | |
| GSE20123 | GTF2E1 | 2960 | 18 | 0 | 12 | |
| GSE43470 | GTF2E1 | 2960 | 21 | 1 | 21 | |
| GSE46452 | GTF2E1 | 2960 | 14 | 5 | 40 | |
| GSE47630 | GTF2E1 | 2960 | 16 | 5 | 19 | |
| GSE54993 | GTF2E1 | 2960 | 2 | 6 | 62 | |
| GSE54994 | GTF2E1 | 2960 | 30 | 4 | 19 | |
| GSE60625 | GTF2E1 | 2960 | 0 | 6 | 5 | |
| GSE74703 | GTF2E1 | 2960 | 17 | 1 | 18 | |
| GSE74704 | GTF2E1 | 2960 | 13 | 0 | 7 | |
| TCGA | GTF2E1 | 2960 | 53 | 7 | 36 |
Total number of gains: 202; Total number of losses: 35; Total Number of normals: 251.
Somatic mutations of GTF2E1:
Generating mutation plots.
Highly correlated genes for GTF2E1:
Showing top 20/2026 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2E1 | CDCA2 | 0.880757 | 3 | 0 | 3 |
| GTF2E1 | NQO2 | 0.7943 | 3 | 0 | 3 |
| GTF2E1 | NRARP | 0.779834 | 3 | 0 | 3 |
| GTF2E1 | TOPBP1 | 0.772228 | 10 | 0 | 10 |
| GTF2E1 | UBE2T | 0.768844 | 5 | 0 | 5 |
| GTF2E1 | ECT2 | 0.767896 | 9 | 0 | 9 |
| GTF2E1 | UBE2C | 0.763139 | 9 | 0 | 9 |
| GTF2E1 | KNSTRN | 0.762903 | 4 | 0 | 4 |
| GTF2E1 | LRRC58 | 0.761299 | 6 | 0 | 6 |
| GTF2E1 | NEK2 | 0.758156 | 9 | 0 | 8 |
| GTF2E1 | CENPL | 0.755917 | 6 | 0 | 6 |
| GTF2E1 | U2SURP | 0.741273 | 9 | 0 | 8 |
| GTF2E1 | C12orf73 | 0.740126 | 3 | 0 | 3 |
| GTF2E1 | WDHD1 | 0.739183 | 11 | 0 | 10 |
| GTF2E1 | NUP107 | 0.73415 | 11 | 0 | 10 |
| GTF2E1 | TNFRSF1A | 0.733546 | 3 | 0 | 3 |
| GTF2E1 | MRPL10 | 0.733303 | 3 | 0 | 3 |
| GTF2E1 | GMNN | 0.73293 | 11 | 0 | 11 |
| GTF2E1 | GMPS | 0.732471 | 12 | 0 | 11 |
| GTF2E1 | KIF20A | 0.731611 | 10 | 0 | 10 |
For details and further investigation, click here
