| Full name: carboxylesterase 4A | Alias Symbol: FLJ37464 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 283848 | HGNC ID: HGNC:26741 | Ensembl Gene: ENSG00000172824 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CES4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CES4A | 283848 | 228903_at | 0.0107 | 0.9779 | |
| GSE26886 | CES4A | 283848 | 228903_at | -0.1434 | 0.4186 | |
| GSE45670 | CES4A | 283848 | 228903_at | 0.0968 | 0.4950 | |
| GSE53622 | CES4A | 283848 | 38422 | -0.4654 | 0.0007 | |
| GSE53624 | CES4A | 283848 | 38422 | -0.4244 | 0.0001 | |
| GSE63941 | CES4A | 283848 | 228903_at | -0.0356 | 0.8566 | |
| GSE77861 | CES4A | 283848 | 228903_at | 0.0867 | 0.6180 | |
| GSE97050 | CES4A | 283848 | A_23_P361544 | 0.0280 | 0.9310 | |
| SRP007169 | CES4A | 283848 | RNAseq | -0.5596 | 0.3189 | |
| SRP064894 | CES4A | 283848 | RNAseq | -0.0397 | 0.8726 | |
| SRP133303 | CES4A | 283848 | RNAseq | -0.3502 | 0.0466 | |
| SRP159526 | CES4A | 283848 | RNAseq | 0.5680 | 0.2593 | |
| SRP193095 | CES4A | 283848 | RNAseq | 0.2649 | 0.2001 | |
| SRP219564 | CES4A | 283848 | RNAseq | -0.7546 | 0.1565 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CES4A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CES4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CES4A | 283848 | 8 | 2 | 20 | |
| GSE20123 | CES4A | 283848 | 8 | 2 | 20 | |
| GSE43470 | CES4A | 283848 | 1 | 9 | 33 | |
| GSE46452 | CES4A | 283848 | 38 | 1 | 20 | |
| GSE47630 | CES4A | 283848 | 10 | 8 | 22 | |
| GSE54993 | CES4A | 283848 | 2 | 4 | 64 | |
| GSE54994 | CES4A | 283848 | 8 | 10 | 35 | |
| GSE60625 | CES4A | 283848 | 4 | 0 | 7 | |
| GSE74703 | CES4A | 283848 | 1 | 6 | 29 | |
| GSE74704 | CES4A | 283848 | 5 | 1 | 14 | |
| TCGA | CES4A | 283848 | 31 | 11 | 54 |
Total number of gains: 116; Total number of losses: 54; Total Number of normals: 318.
Somatic mutations of CES4A:
Generating mutation plots.
Highly correlated genes for CES4A:
Showing top 20/55 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CES4A | ANKZF1 | 0.663381 | 3 | 0 | 3 |
| CES4A | TMEM154 | 0.651723 | 3 | 0 | 3 |
| CES4A | IL5 | 0.64148 | 3 | 0 | 3 |
| CES4A | CXorf21 | 0.634784 | 3 | 0 | 3 |
| CES4A | MEX3A | 0.61528 | 3 | 0 | 3 |
| CES4A | STXBP2 | 0.615196 | 3 | 0 | 3 |
| CES4A | SDC1 | 0.610547 | 4 | 0 | 4 |
| CES4A | PKP3 | 0.604366 | 3 | 0 | 3 |
| CES4A | ANKRD24 | 0.599587 | 4 | 0 | 3 |
| CES4A | PLEKHN1 | 0.598913 | 5 | 0 | 4 |
| CES4A | KRT6C | 0.596868 | 3 | 0 | 3 |
| CES4A | EGR4 | 0.594208 | 3 | 0 | 3 |
| CES4A | TMEM134 | 0.592855 | 4 | 0 | 4 |
| CES4A | CRB3 | 0.59246 | 4 | 0 | 3 |
| CES4A | ZBTB7B | 0.584953 | 5 | 0 | 4 |
| CES4A | SLC7A10 | 0.584211 | 4 | 0 | 3 |
| CES4A | PGLYRP3 | 0.583345 | 3 | 0 | 3 |
| CES4A | PLD2 | 0.580046 | 4 | 0 | 4 |
| CES4A | USH1G | 0.576242 | 3 | 0 | 3 |
| CES4A | C10orf99 | 0.5706 | 4 | 0 | 3 |
For details and further investigation, click here
