| Full name: mex-3 RNA binding family member A | Alias Symbol: RNF162 | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 92312 | HGNC ID: HGNC:33482 | Ensembl Gene: ENSG00000254726 | OMIM ID: 611007 |
| Drug and gene relationship at DGIdb | |||
Expression of MEX3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEX3A | 92312 | 236885_at | 0.2715 | 0.3188 | |
| GSE26886 | MEX3A | 92312 | 236885_at | 0.4980 | 0.0020 | |
| GSE45670 | MEX3A | 92312 | 236885_at | 0.0541 | 0.6473 | |
| GSE53622 | MEX3A | 92312 | 93196 | -0.4132 | 0.0000 | |
| GSE53624 | MEX3A | 92312 | 93196 | -0.9079 | 0.0000 | |
| GSE63941 | MEX3A | 92312 | 227512_at | 0.5108 | 0.2500 | |
| GSE77861 | MEX3A | 92312 | 227512_at | 0.0793 | 0.4815 | |
| GSE97050 | MEX3A | 92312 | A_32_P96036 | 0.6522 | 0.1703 | |
| SRP007169 | MEX3A | 92312 | RNAseq | 1.6481 | 0.0588 | |
| SRP008496 | MEX3A | 92312 | RNAseq | 1.9157 | 0.0237 | |
| SRP064894 | MEX3A | 92312 | RNAseq | 1.4280 | 0.0000 | |
| SRP133303 | MEX3A | 92312 | RNAseq | 1.2762 | 0.0001 | |
| SRP159526 | MEX3A | 92312 | RNAseq | 3.1194 | 0.0002 | |
| SRP193095 | MEX3A | 92312 | RNAseq | 1.1409 | 0.0001 | |
| SRP219564 | MEX3A | 92312 | RNAseq | 0.4607 | 0.4417 | |
| TCGA | MEX3A | 92312 | RNAseq | 0.9493 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by MEX3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEX3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEX3A | 92312 | 14 | 0 | 16 | |
| GSE20123 | MEX3A | 92312 | 13 | 0 | 17 | |
| GSE43470 | MEX3A | 92312 | 7 | 2 | 34 | |
| GSE46452 | MEX3A | 92312 | 2 | 1 | 56 | |
| GSE47630 | MEX3A | 92312 | 14 | 0 | 26 | |
| GSE54993 | MEX3A | 92312 | 0 | 5 | 65 | |
| GSE54994 | MEX3A | 92312 | 16 | 0 | 37 | |
| GSE60625 | MEX3A | 92312 | 0 | 0 | 11 | |
| GSE74703 | MEX3A | 92312 | 7 | 2 | 27 | |
| GSE74704 | MEX3A | 92312 | 6 | 0 | 14 | |
| TCGA | MEX3A | 92312 | 38 | 2 | 56 |
Total number of gains: 117; Total number of losses: 12; Total Number of normals: 359.
Somatic mutations of MEX3A:
Generating mutation plots.
Highly correlated genes for MEX3A:
Showing top 20/124 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEX3A | ENTPD6 | 0.742328 | 3 | 0 | 3 |
| MEX3A | RUVBL2 | 0.725942 | 3 | 0 | 3 |
| MEX3A | FAM181A | 0.711314 | 3 | 0 | 3 |
| MEX3A | RAC3 | 0.705175 | 3 | 0 | 3 |
| MEX3A | ZMYND15 | 0.698014 | 3 | 0 | 3 |
| MEX3A | NOC4L | 0.670582 | 3 | 0 | 3 |
| MEX3A | PODXL2 | 0.660829 | 7 | 0 | 5 |
| MEX3A | FABP6 | 0.644068 | 3 | 0 | 3 |
| MEX3A | AGAP2 | 0.641487 | 3 | 0 | 3 |
| MEX3A | L3MBTL1 | 0.64127 | 3 | 0 | 3 |
| MEX3A | RBFOX1 | 0.636148 | 3 | 0 | 3 |
| MEX3A | TFR2 | 0.629553 | 3 | 0 | 3 |
| MEX3A | PM20D1 | 0.621301 | 3 | 0 | 3 |
| MEX3A | NPHS1 | 0.621127 | 3 | 0 | 3 |
| MEX3A | FAM83E | 0.620502 | 3 | 0 | 3 |
| MEX3A | RTEL1 | 0.619271 | 3 | 0 | 3 |
| MEX3A | RECQL4 | 0.617799 | 4 | 0 | 3 |
| MEX3A | SHARPIN | 0.616411 | 4 | 0 | 3 |
| MEX3A | CD164L2 | 0.615561 | 3 | 0 | 3 |
| MEX3A | CES4A | 0.61528 | 3 | 0 | 3 |
For details and further investigation, click here
