| Full name: transmembrane protein 134 | Alias Symbol: FLJ21749 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 80194 | HGNC ID: HGNC:26142 | Ensembl Gene: ENSG00000172663 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM134:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM134 | 80194 | 218531_at | -0.3222 | 0.4762 | |
| GSE20347 | TMEM134 | 80194 | 218531_at | -0.5371 | 0.0034 | |
| GSE23400 | TMEM134 | 80194 | 218531_at | -0.4525 | 0.0000 | |
| GSE26886 | TMEM134 | 80194 | 218531_at | -0.5486 | 0.0097 | |
| GSE29001 | TMEM134 | 80194 | 218531_at | -0.6747 | 0.0368 | |
| GSE38129 | TMEM134 | 80194 | 218531_at | -0.2249 | 0.3275 | |
| GSE45670 | TMEM134 | 80194 | 218531_at | -0.2205 | 0.2077 | |
| GSE53622 | TMEM134 | 80194 | 131357 | -0.6429 | 0.0000 | |
| GSE53624 | TMEM134 | 80194 | 11607 | -0.6719 | 0.0000 | |
| GSE63941 | TMEM134 | 80194 | 218531_at | 0.3650 | 0.5521 | |
| GSE77861 | TMEM134 | 80194 | 218531_at | -0.3081 | 0.2132 | |
| GSE97050 | TMEM134 | 80194 | A_23_P161522 | 0.1661 | 0.6391 | |
| SRP007169 | TMEM134 | 80194 | RNAseq | -2.2618 | 0.0000 | |
| SRP008496 | TMEM134 | 80194 | RNAseq | -1.9724 | 0.0000 | |
| SRP064894 | TMEM134 | 80194 | RNAseq | -0.8927 | 0.0006 | |
| SRP133303 | TMEM134 | 80194 | RNAseq | -0.5877 | 0.0008 | |
| SRP159526 | TMEM134 | 80194 | RNAseq | -1.0152 | 0.0000 | |
| SRP193095 | TMEM134 | 80194 | RNAseq | -0.8239 | 0.0000 | |
| SRP219564 | TMEM134 | 80194 | RNAseq | -0.9208 | 0.0538 | |
| TCGA | TMEM134 | 80194 | RNAseq | 0.0951 | 0.2170 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMEM134 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM134:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM134 | 80194 | 10 | 3 | 17 | |
| GSE20123 | TMEM134 | 80194 | 10 | 3 | 17 | |
| GSE43470 | TMEM134 | 80194 | 5 | 2 | 36 | |
| GSE46452 | TMEM134 | 80194 | 14 | 3 | 42 | |
| GSE47630 | TMEM134 | 80194 | 8 | 5 | 27 | |
| GSE54993 | TMEM134 | 80194 | 3 | 1 | 66 | |
| GSE54994 | TMEM134 | 80194 | 13 | 4 | 36 | |
| GSE60625 | TMEM134 | 80194 | 0 | 3 | 8 | |
| GSE74703 | TMEM134 | 80194 | 4 | 1 | 31 | |
| GSE74704 | TMEM134 | 80194 | 8 | 1 | 11 | |
| TCGA | TMEM134 | 80194 | 29 | 8 | 59 |
Total number of gains: 104; Total number of losses: 34; Total Number of normals: 350.
Somatic mutations of TMEM134:
Generating mutation plots.
Highly correlated genes for TMEM134:
Showing top 20/1040 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM134 | NIPAL1 | 0.741664 | 3 | 0 | 3 |
| TMEM134 | DMKN | 0.732908 | 5 | 0 | 4 |
| TMEM134 | NUAK2 | 0.726085 | 3 | 0 | 3 |
| TMEM134 | S100A16 | 0.721137 | 6 | 0 | 6 |
| TMEM134 | CYSRT1 | 0.719864 | 4 | 0 | 4 |
| TMEM134 | ARAP2 | 0.719813 | 3 | 0 | 3 |
| TMEM134 | BNIPL | 0.716091 | 5 | 0 | 5 |
| TMEM134 | A2ML1 | 0.715777 | 5 | 0 | 5 |
| TMEM134 | UPK3B | 0.712816 | 3 | 0 | 3 |
| TMEM134 | LTA4H | 0.707846 | 3 | 0 | 3 |
| TMEM134 | NSDHL | 0.706457 | 8 | 0 | 7 |
| TMEM134 | EPGN | 0.705644 | 3 | 0 | 3 |
| TMEM134 | IL20RB | 0.695001 | 5 | 0 | 5 |
| TMEM134 | MPZL3 | 0.694955 | 5 | 0 | 5 |
| TMEM134 | RPS6KB2 | 0.693485 | 13 | 0 | 12 |
| TMEM134 | RARG | 0.691766 | 10 | 0 | 10 |
| TMEM134 | LAD1 | 0.691061 | 10 | 0 | 10 |
| TMEM134 | RAPGEFL1 | 0.689569 | 8 | 0 | 7 |
| TMEM134 | USH1G | 0.688148 | 5 | 0 | 5 |
| TMEM134 | C7orf57 | 0.686553 | 3 | 0 | 3 |
For details and further investigation, click here
