| Full name: protein phosphatase 2 regulatory subunit B'gamma | Alias Symbol: B56G|PR61G|B56gamma | ||
| Type: protein-coding gene | Cytoband: 14q32.31 | ||
| Entrez ID: 5527 | HGNC ID: HGNC:9311 | Ensembl Gene: ENSG00000078304 | OMIM ID: 601645 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
PPP2R5C involved pathways:
Expression of PPP2R5C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R5C | 5527 | 201877_s_at | -0.0664 | 0.9075 | |
| GSE20347 | PPP2R5C | 5527 | 201877_s_at | -0.4973 | 0.0008 | |
| GSE23400 | PPP2R5C | 5527 | 201877_s_at | -0.0223 | 0.8334 | |
| GSE26886 | PPP2R5C | 5527 | 201877_s_at | -0.3051 | 0.1113 | |
| GSE29001 | PPP2R5C | 5527 | 201877_s_at | -0.0560 | 0.8295 | |
| GSE38129 | PPP2R5C | 5527 | 201877_s_at | -0.4832 | 0.0003 | |
| GSE45670 | PPP2R5C | 5527 | 201877_s_at | -0.2158 | 0.1723 | |
| GSE53622 | PPP2R5C | 5527 | 22755 | -0.0303 | 0.6740 | |
| GSE53624 | PPP2R5C | 5527 | 22755 | -0.0522 | 0.4347 | |
| GSE63941 | PPP2R5C | 5527 | 201877_s_at | 0.4203 | 0.2279 | |
| GSE77861 | PPP2R5C | 5527 | 201877_s_at | -0.3412 | 0.3480 | |
| GSE97050 | PPP2R5C | 5527 | A_24_P369694 | -0.0590 | 0.8301 | |
| SRP007169 | PPP2R5C | 5527 | RNAseq | -0.8112 | 0.0126 | |
| SRP008496 | PPP2R5C | 5527 | RNAseq | -0.8072 | 0.0001 | |
| SRP064894 | PPP2R5C | 5527 | RNAseq | -0.1268 | 0.3961 | |
| SRP133303 | PPP2R5C | 5527 | RNAseq | 0.1317 | 0.2748 | |
| SRP159526 | PPP2R5C | 5527 | RNAseq | -0.1065 | 0.7836 | |
| SRP193095 | PPP2R5C | 5527 | RNAseq | -0.3159 | 0.0058 | |
| SRP219564 | PPP2R5C | 5527 | RNAseq | -0.3411 | 0.3065 | |
| TCGA | PPP2R5C | 5527 | RNAseq | -0.0417 | 0.3376 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP2R5C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R5C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R5C | 5527 | 10 | 5 | 15 | |
| GSE20123 | PPP2R5C | 5527 | 9 | 4 | 17 | |
| GSE43470 | PPP2R5C | 5527 | 7 | 4 | 32 | |
| GSE46452 | PPP2R5C | 5527 | 18 | 4 | 37 | |
| GSE47630 | PPP2R5C | 5527 | 10 | 9 | 21 | |
| GSE54993 | PPP2R5C | 5527 | 3 | 8 | 59 | |
| GSE54994 | PPP2R5C | 5527 | 21 | 4 | 28 | |
| GSE60625 | PPP2R5C | 5527 | 0 | 2 | 9 | |
| GSE74703 | PPP2R5C | 5527 | 6 | 3 | 27 | |
| GSE74704 | PPP2R5C | 5527 | 5 | 3 | 12 | |
| TCGA | PPP2R5C | 5527 | 32 | 18 | 46 |
Total number of gains: 121; Total number of losses: 64; Total Number of normals: 303.
Somatic mutations of PPP2R5C:
Generating mutation plots.
Highly correlated genes for PPP2R5C:
Showing top 20/380 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R5C | CRIP1 | 0.78128 | 4 | 0 | 4 |
| PPP2R5C | REEP5 | 0.778706 | 4 | 0 | 4 |
| PPP2R5C | BBIP1 | 0.759996 | 3 | 0 | 3 |
| PPP2R5C | PCSK5 | 0.738963 | 3 | 0 | 3 |
| PPP2R5C | CGGBP1 | 0.715772 | 3 | 0 | 3 |
| PPP2R5C | FOXN3 | 0.715434 | 7 | 0 | 7 |
| PPP2R5C | DHDH | 0.709434 | 4 | 0 | 4 |
| PPP2R5C | STAG2 | 0.708776 | 3 | 0 | 3 |
| PPP2R5C | CAMK1 | 0.704937 | 4 | 0 | 4 |
| PPP2R5C | UBE2D2 | 0.696391 | 3 | 0 | 3 |
| PPP2R5C | RBM18 | 0.693925 | 4 | 0 | 3 |
| PPP2R5C | GPHN | 0.693044 | 4 | 0 | 4 |
| PPP2R5C | EFCAB7 | 0.692347 | 3 | 0 | 3 |
| PPP2R5C | EMP2 | 0.690962 | 3 | 0 | 3 |
| PPP2R5C | IDH3G | 0.690778 | 3 | 0 | 3 |
| PPP2R5C | WDR20 | 0.689374 | 7 | 0 | 6 |
| PPP2R5C | FNTA | 0.68639 | 3 | 0 | 3 |
| PPP2R5C | HNRNPA0 | 0.686076 | 5 | 0 | 4 |
| PPP2R5C | KIF13B | 0.685854 | 4 | 0 | 4 |
| PPP2R5C | PSMG2 | 0.679244 | 4 | 0 | 3 |
For details and further investigation, click here
