| Full name: WD repeat domain 78 | Alias Symbol: DIC4|FLJ23129 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 79819 | HGNC ID: HGNC:26252 | Ensembl Gene: ENSG00000152763 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR78:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR78 | 79819 | 1559576_at | 0.0815 | 0.8084 | |
| GSE20347 | WDR78 | 79819 | 220769_s_at | 0.0725 | 0.2031 | |
| GSE23400 | WDR78 | 79819 | 220769_s_at | -0.0364 | 0.1340 | |
| GSE26886 | WDR78 | 79819 | 1559576_at | -0.0220 | 0.8848 | |
| GSE29001 | WDR78 | 79819 | 220769_s_at | -0.1503 | 0.2133 | |
| GSE38129 | WDR78 | 79819 | 220769_s_at | 0.0387 | 0.5453 | |
| GSE45670 | WDR78 | 79819 | 1559576_at | 0.0629 | 0.5490 | |
| GSE53622 | WDR78 | 79819 | 86182 | 0.0576 | 0.7261 | |
| GSE53624 | WDR78 | 79819 | 86182 | 0.5426 | 0.0000 | |
| GSE63941 | WDR78 | 79819 | 1559576_at | 0.6994 | 0.0634 | |
| GSE77861 | WDR78 | 79819 | 1559576_at | -0.0751 | 0.4067 | |
| GSE97050 | WDR78 | 79819 | A_23_P200670 | -0.0210 | 0.9381 | |
| SRP007169 | WDR78 | 79819 | RNAseq | 0.6491 | 0.3840 | |
| SRP064894 | WDR78 | 79819 | RNAseq | 1.0664 | 0.0003 | |
| SRP133303 | WDR78 | 79819 | RNAseq | -0.1581 | 0.5917 | |
| SRP159526 | WDR78 | 79819 | RNAseq | 0.8631 | 0.0986 | |
| SRP193095 | WDR78 | 79819 | RNAseq | 0.1503 | 0.5471 | |
| SRP219564 | WDR78 | 79819 | RNAseq | 1.2095 | 0.0823 | |
| TCGA | WDR78 | 79819 | RNAseq | -0.4593 | 0.0544 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by WDR78 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR78:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR78 | 79819 | 1 | 6 | 23 | |
| GSE20123 | WDR78 | 79819 | 1 | 5 | 24 | |
| GSE43470 | WDR78 | 79819 | 5 | 2 | 36 | |
| GSE46452 | WDR78 | 79819 | 0 | 1 | 58 | |
| GSE47630 | WDR78 | 79819 | 8 | 5 | 27 | |
| GSE54993 | WDR78 | 79819 | 0 | 0 | 70 | |
| GSE54994 | WDR78 | 79819 | 6 | 4 | 43 | |
| GSE60625 | WDR78 | 79819 | 0 | 0 | 11 | |
| GSE74703 | WDR78 | 79819 | 4 | 2 | 30 | |
| GSE74704 | WDR78 | 79819 | 1 | 2 | 17 | |
| TCGA | WDR78 | 79819 | 9 | 22 | 65 |
Total number of gains: 35; Total number of losses: 49; Total Number of normals: 404.
Somatic mutations of WDR78:
Generating mutation plots.
Highly correlated genes for WDR78:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR78 | AQP4 | 0.743284 | 3 | 0 | 3 |
| WDR78 | GRIN1 | 0.738114 | 3 | 0 | 3 |
| WDR78 | PGC | 0.727561 | 3 | 0 | 3 |
| WDR78 | SEC14L3 | 0.707743 | 3 | 0 | 3 |
| WDR78 | ALAS2 | 0.703026 | 3 | 0 | 3 |
| WDR78 | RAP1GAP | 0.694961 | 3 | 0 | 3 |
| WDR78 | CHRNA10 | 0.6907 | 3 | 0 | 3 |
| WDR78 | SCLY | 0.684214 | 3 | 0 | 3 |
| WDR78 | LCT | 0.678607 | 5 | 0 | 5 |
| WDR78 | SLC12A3 | 0.674745 | 4 | 0 | 4 |
| WDR78 | EML6 | 0.67365 | 3 | 0 | 3 |
| WDR78 | RNF17 | 0.662942 | 4 | 0 | 3 |
| WDR78 | TLR8 | 0.662429 | 4 | 0 | 4 |
| WDR78 | SPTBN5 | 0.653609 | 4 | 0 | 3 |
| WDR78 | RAD52 | 0.653053 | 4 | 0 | 4 |
| WDR78 | KRT32 | 0.650912 | 3 | 0 | 3 |
| WDR78 | PICK1 | 0.649483 | 3 | 0 | 3 |
| WDR78 | PSG9 | 0.649454 | 3 | 0 | 3 |
| WDR78 | SHC2 | 0.642838 | 4 | 0 | 3 |
| WDR78 | LUZP4 | 0.641998 | 3 | 0 | 3 |
For details and further investigation, click here
