TTYH3

 

Full name: tweety family member 3 Alias Symbol: KIAA1691
Type: protein-coding gene Cytoband: 7p22.3
Entrez ID: 80727 HGNC ID: HGNC:22222 Ensembl Gene: ENSG00000136295 OMIM ID: 608919
Drug and gene relationship at DGIdb

 

Expression of TTYH3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TTYH3 80727 224674_at 1.0580 0.0289
GSE26886 TTYH3 80727 224674_at 0.6054 0.0015
GSE45670 TTYH3 80727 224674_at 0.6860 0.0001
GSE53622 TTYH3 80727 18977 2.2564 0.0000
GSE53624 TTYH3 80727 18977 2.4104 0.0000
GSE63941 TTYH3 80727 224674_at 0.3885 0.4233
GSE77861 TTYH3 80727 224674_at 0.7691 0.0186
GSE97050 TTYH3 80727 A_23_P331895 1.7698 0.0903
SRP007169 TTYH3 80727 RNAseq 3.4095 0.0000
SRP008496 TTYH3 80727 RNAseq 2.7718 0.0000
SRP064894 TTYH3 80727 RNAseq 2.0654 0.0000
SRP133303 TTYH3 80727 RNAseq 2.2905 0.0000
SRP159526 TTYH3 80727 RNAseq 2.4777 0.0000
SRP193095 TTYH3 80727 RNAseq 2.1166 0.0000
SRP219564 TTYH3 80727 RNAseq 1.8438 0.0009
TCGA TTYH3 80727 RNAseq 0.5021 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by TTYH3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TTYH3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TTYH3 80727 15 0 15
GSE20123 TTYH3 80727 14 0 16
GSE43470 TTYH3 80727 7 2 34
GSE46452 TTYH3 80727 13 1 45
GSE47630 TTYH3 80727 10 1 29
GSE54993 TTYH3 80727 0 7 63
GSE54994 TTYH3 80727 21 2 30
GSE60625 TTYH3 80727 0 0 11
GSE74703 TTYH3 80727 7 1 28
GSE74704 TTYH3 80727 9 0 11
TCGA TTYH3 80727 56 5 35

Total number of gains: 152; Total number of losses: 19; Total Number of normals: 317.  

 

Somatic mutations of TTYH3:

 

Generating mutation plots.

 

Highly correlated genes for TTYH3:

 

Showing top 20/1815 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TTYH3CTHRC10.827017707
TTYH3SERPINE10.800159707
TTYH3MFAP20.799074808
TTYH3ADAMTS120.798708707
TTYH3LOXL20.798632707
TTYH3PDIA50.795145303
TTYH3XPR10.78575707
TTYH3FNDC3B0.783882707
TTYH3RUNX1-IT10.781822404
TTYH3USB10.780458606
TTYH3C4orf480.780418707
TTYH3HOXD110.779942707
TTYH3SNX100.779532807
TTYH3TGFBI0.774694707
TTYH3SPP10.773242707
TTYH3WDR660.772927707
TTYH3ARPC1B0.772611707
TTYH3SLC19A10.77162303
TTYH3PTK70.77036807
TTYH3LRRC8D0.769774707

For details and further investigation, click here