| Full name: cartilage intermediate layer protein | Alias Symbol: HsT18872 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 8483 | HGNC ID: HGNC:1980 | Ensembl Gene: ENSG00000138615 | OMIM ID: 603489 |
| Drug and gene relationship at DGIdb | |||
Expression of CILP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CILP | 8483 | 206227_at | -1.9334 | 0.1465 | |
| GSE20347 | CILP | 8483 | 206227_at | -0.3722 | 0.1031 | |
| GSE23400 | CILP | 8483 | 206227_at | -0.6262 | 0.0000 | |
| GSE26886 | CILP | 8483 | 206227_at | -0.1134 | 0.7298 | |
| GSE29001 | CILP | 8483 | 206227_at | -0.6849 | 0.0034 | |
| GSE38129 | CILP | 8483 | 206227_at | -0.8891 | 0.0315 | |
| GSE45670 | CILP | 8483 | 206227_at | -3.0474 | 0.0000 | |
| GSE53622 | CILP | 8483 | 35147 | -2.2078 | 0.0000 | |
| GSE53624 | CILP | 8483 | 35147 | -2.0895 | 0.0000 | |
| GSE63941 | CILP | 8483 | 206227_at | 0.0107 | 0.9826 | |
| GSE77861 | CILP | 8483 | 206227_at | -0.1770 | 0.2038 | |
| GSE97050 | CILP | 8483 | A_23_P151895 | -0.6555 | 0.3249 | |
| SRP064894 | CILP | 8483 | RNAseq | -0.5084 | 0.3607 | |
| SRP133303 | CILP | 8483 | RNAseq | -0.9836 | 0.0721 | |
| SRP159526 | CILP | 8483 | RNAseq | -2.2379 | 0.0004 | |
| SRP219564 | CILP | 8483 | RNAseq | -0.3988 | 0.7003 | |
| TCGA | CILP | 8483 | RNAseq | -1.0556 | 0.0048 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CILP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CILP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CILP | 8483 | 7 | 3 | 20 | |
| GSE20123 | CILP | 8483 | 7 | 3 | 20 | |
| GSE43470 | CILP | 8483 | 4 | 6 | 33 | |
| GSE46452 | CILP | 8483 | 3 | 7 | 49 | |
| GSE47630 | CILP | 8483 | 8 | 10 | 22 | |
| GSE54993 | CILP | 8483 | 5 | 6 | 59 | |
| GSE54994 | CILP | 8483 | 6 | 7 | 40 | |
| GSE60625 | CILP | 8483 | 4 | 0 | 7 | |
| GSE74703 | CILP | 8483 | 4 | 3 | 29 | |
| GSE74704 | CILP | 8483 | 3 | 3 | 14 | |
| TCGA | CILP | 8483 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of CILP:
Generating mutation plots.
Highly correlated genes for CILP:
Showing top 20/1200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CILP | DPT | 0.823651 | 10 | 0 | 10 |
| CILP | CYP21A2 | 0.820265 | 3 | 0 | 3 |
| CILP | LRRN4CL | 0.82026 | 5 | 0 | 5 |
| CILP | KCNT2 | 0.799027 | 5 | 0 | 5 |
| CILP | ANGPTL1 | 0.79424 | 6 | 0 | 6 |
| CILP | AOC3 | 0.788497 | 9 | 0 | 9 |
| CILP | RBPMS2 | 0.786162 | 5 | 0 | 5 |
| CILP | DIXDC1 | 0.784589 | 8 | 0 | 8 |
| CILP | FBXL3 | 0.783259 | 3 | 0 | 3 |
| CILP | AGTR1 | 0.783128 | 9 | 0 | 9 |
| CILP | TCF21 | 0.782507 | 9 | 0 | 9 |
| CILP | OGN | 0.780469 | 12 | 0 | 11 |
| CILP | XKR4 | 0.777047 | 5 | 0 | 5 |
| CILP | DAAM2 | 0.776757 | 8 | 0 | 7 |
| CILP | LRFN5 | 0.775742 | 4 | 0 | 4 |
| CILP | MEOX2 | 0.774986 | 9 | 0 | 9 |
| CILP | CHRDL1 | 0.772863 | 9 | 0 | 7 |
| CILP | CLEC3B | 0.771833 | 3 | 0 | 3 |
| CILP | C1QTNF7 | 0.763391 | 6 | 0 | 6 |
| CILP | KANK2 | 0.753869 | 8 | 0 | 7 |
For details and further investigation, click here
