| Full name: C-type lectin domain family 2 member B | Alias Symbol: AICL|HP10085 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 9976 | HGNC ID: HGNC:2053 | Ensembl Gene: ENSG00000110852 | OMIM ID: 603242 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC2B | 9976 | 209732_at | 0.3070 | 0.6488 | |
| GSE20347 | CLEC2B | 9976 | 209732_at | 0.3427 | 0.3577 | |
| GSE23400 | CLEC2B | 9976 | 209732_at | 0.3005 | 0.0664 | |
| GSE26886 | CLEC2B | 9976 | 209732_at | -0.1622 | 0.8012 | |
| GSE29001 | CLEC2B | 9976 | 209732_at | 0.5398 | 0.4759 | |
| GSE38129 | CLEC2B | 9976 | 209732_at | 0.3091 | 0.2900 | |
| GSE45670 | CLEC2B | 9976 | 209732_at | 0.6645 | 0.1096 | |
| GSE63941 | CLEC2B | 9976 | 209732_at | -4.0495 | 0.0619 | |
| GSE77861 | CLEC2B | 9976 | 209732_at | 0.0092 | 0.9917 | |
| GSE97050 | CLEC2B | 9976 | A_33_P3332970 | 0.0322 | 0.8949 | |
| SRP007169 | CLEC2B | 9976 | RNAseq | -0.6889 | 0.1545 | |
| SRP008496 | CLEC2B | 9976 | RNAseq | -0.8741 | 0.0238 | |
| SRP064894 | CLEC2B | 9976 | RNAseq | 0.5308 | 0.0262 | |
| SRP133303 | CLEC2B | 9976 | RNAseq | 0.6014 | 0.0947 | |
| SRP159526 | CLEC2B | 9976 | RNAseq | -0.8600 | 0.0838 | |
| SRP193095 | CLEC2B | 9976 | RNAseq | 0.3512 | 0.2561 | |
| SRP219564 | CLEC2B | 9976 | RNAseq | 0.8122 | 0.0909 | |
| TCGA | CLEC2B | 9976 | RNAseq | 0.6456 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLEC2B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CLEC2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC2B | 9976 | 6 | 3 | 21 | |
| GSE20123 | CLEC2B | 9976 | 6 | 3 | 21 | |
| GSE43470 | CLEC2B | 9976 | 8 | 3 | 32 | |
| GSE46452 | CLEC2B | 9976 | 10 | 1 | 48 | |
| GSE47630 | CLEC2B | 9976 | 14 | 2 | 24 | |
| GSE54993 | CLEC2B | 9976 | 1 | 10 | 59 | |
| GSE54994 | CLEC2B | 9976 | 9 | 2 | 42 | |
| GSE60625 | CLEC2B | 9976 | 0 | 1 | 10 | |
| GSE74703 | CLEC2B | 9976 | 8 | 2 | 26 | |
| GSE74704 | CLEC2B | 9976 | 4 | 2 | 14 | |
| TCGA | CLEC2B | 9976 | 40 | 6 | 50 |
Total number of gains: 106; Total number of losses: 35; Total Number of normals: 347.
Somatic mutations of CLEC2B:
Generating mutation plots.
Highly correlated genes for CLEC2B:
Showing top 20/169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC2B | CEP70 | 0.769798 | 3 | 0 | 3 |
| CLEC2B | MORF4L1 | 0.750448 | 3 | 0 | 3 |
| CLEC2B | PTPRK | 0.748062 | 3 | 0 | 3 |
| CLEC2B | TSPAN5 | 0.723385 | 4 | 0 | 4 |
| CLEC2B | MBTPS2 | 0.720383 | 3 | 0 | 3 |
| CLEC2B | RPL26L1 | 0.711678 | 3 | 0 | 3 |
| CLEC2B | WARS2 | 0.707688 | 4 | 0 | 4 |
| CLEC2B | AXL | 0.69511 | 3 | 0 | 3 |
| CLEC2B | GLIS3 | 0.687794 | 3 | 0 | 3 |
| CLEC2B | SNX30 | 0.686899 | 3 | 0 | 3 |
| CLEC2B | ZKSCAN5 | 0.686383 | 3 | 0 | 3 |
| CLEC2B | EIF2B1 | 0.685587 | 3 | 0 | 3 |
| CLEC2B | MTCH1 | 0.678527 | 3 | 0 | 3 |
| CLEC2B | PRDX3 | 0.678236 | 4 | 0 | 3 |
| CLEC2B | JAK1 | 0.672236 | 4 | 0 | 3 |
| CLEC2B | SERINC3 | 0.666808 | 5 | 0 | 4 |
| CLEC2B | PCMTD2 | 0.664748 | 4 | 0 | 3 |
| CLEC2B | DNAJB14 | 0.66473 | 3 | 0 | 3 |
| CLEC2B | LRP11 | 0.664617 | 3 | 0 | 3 |
| CLEC2B | PIGU | 0.663291 | 3 | 0 | 3 |
For details and further investigation, click here
