| Full name: serine incorporator 3 | Alias Symbol: DIFF33|TDE|SBBI99|TMS-1|AIGP1 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 10955 | HGNC ID: HGNC:11699 | Ensembl Gene: ENSG00000132824 | OMIM ID: 607165 |
| Drug and gene relationship at DGIdb | |||
Expression of SERINC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERINC3 | 10955 | 221471_at | 0.4124 | 0.2611 | |
| GSE20347 | SERINC3 | 10955 | 221471_at | 0.1004 | 0.5723 | |
| GSE23400 | SERINC3 | 10955 | 211769_x_at | 0.2478 | 0.0077 | |
| GSE26886 | SERINC3 | 10955 | 221471_at | -0.0562 | 0.8180 | |
| GSE29001 | SERINC3 | 10955 | 221471_at | 0.2875 | 0.3145 | |
| GSE38129 | SERINC3 | 10955 | 221471_at | 0.1872 | 0.1112 | |
| GSE45670 | SERINC3 | 10955 | 221471_at | 0.3015 | 0.0262 | |
| GSE53622 | SERINC3 | 10955 | 60425 | 0.3237 | 0.0000 | |
| GSE53624 | SERINC3 | 10955 | 60425 | 0.2078 | 0.0005 | |
| GSE63941 | SERINC3 | 10955 | 221471_at | -0.7718 | 0.0921 | |
| GSE77861 | SERINC3 | 10955 | 221471_at | 0.0390 | 0.9005 | |
| GSE97050 | SERINC3 | 10955 | A_23_P435501 | 0.2736 | 0.4630 | |
| SRP007169 | SERINC3 | 10955 | RNAseq | -0.7087 | 0.0504 | |
| SRP008496 | SERINC3 | 10955 | RNAseq | -0.5085 | 0.0553 | |
| SRP064894 | SERINC3 | 10955 | RNAseq | 0.0507 | 0.7255 | |
| SRP133303 | SERINC3 | 10955 | RNAseq | 0.3316 | 0.0051 | |
| SRP159526 | SERINC3 | 10955 | RNAseq | 0.0412 | 0.8776 | |
| SRP193095 | SERINC3 | 10955 | RNAseq | -0.0372 | 0.7409 | |
| SRP219564 | SERINC3 | 10955 | RNAseq | 0.1290 | 0.5843 | |
| TCGA | SERINC3 | 10955 | RNAseq | -0.0233 | 0.5926 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SERINC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERINC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERINC3 | 10955 | 13 | 1 | 16 | |
| GSE20123 | SERINC3 | 10955 | 13 | 1 | 16 | |
| GSE43470 | SERINC3 | 10955 | 12 | 2 | 29 | |
| GSE46452 | SERINC3 | 10955 | 29 | 0 | 30 | |
| GSE47630 | SERINC3 | 10955 | 24 | 1 | 15 | |
| GSE54993 | SERINC3 | 10955 | 0 | 17 | 53 | |
| GSE54994 | SERINC3 | 10955 | 25 | 0 | 28 | |
| GSE60625 | SERINC3 | 10955 | 0 | 0 | 11 | |
| GSE74703 | SERINC3 | 10955 | 10 | 2 | 24 | |
| GSE74704 | SERINC3 | 10955 | 9 | 0 | 11 | |
| TCGA | SERINC3 | 10955 | 46 | 3 | 47 |
Total number of gains: 181; Total number of losses: 27; Total Number of normals: 280.
Somatic mutations of SERINC3:
Generating mutation plots.
Highly correlated genes for SERINC3:
Showing top 20/414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERINC3 | ELMOD2 | 0.726785 | 3 | 0 | 3 |
| SERINC3 | KIAA0319L | 0.716542 | 3 | 0 | 3 |
| SERINC3 | ATF1 | 0.700328 | 3 | 0 | 3 |
| SERINC3 | SLC7A6OS | 0.69988 | 4 | 0 | 4 |
| SERINC3 | WDR4 | 0.688947 | 4 | 0 | 4 |
| SERINC3 | ISY1 | 0.685589 | 4 | 0 | 3 |
| SERINC3 | NTPCR | 0.683373 | 3 | 0 | 3 |
| SERINC3 | NEK11 | 0.682712 | 5 | 0 | 4 |
| SERINC3 | CHD4 | 0.681955 | 3 | 0 | 3 |
| SERINC3 | MTHFD1 | 0.677871 | 4 | 0 | 3 |
| SERINC3 | VAPA | 0.675187 | 3 | 0 | 3 |
| SERINC3 | ELF4 | 0.674685 | 3 | 0 | 3 |
| SERINC3 | AHCY | 0.674226 | 5 | 0 | 4 |
| SERINC3 | GTPBP4 | 0.674185 | 3 | 0 | 3 |
| SERINC3 | TOMM40L | 0.672014 | 3 | 0 | 3 |
| SERINC3 | PALB2 | 0.670102 | 3 | 0 | 3 |
| SERINC3 | RPS21 | 0.669018 | 6 | 0 | 3 |
| SERINC3 | TMEM63B | 0.668073 | 3 | 0 | 3 |
| SERINC3 | CLEC2B | 0.666808 | 5 | 0 | 4 |
| SERINC3 | DYRK2 | 0.666428 | 4 | 0 | 3 |
For details and further investigation, click here
