| Full name: CLPTM1 regulator of GABA type A receptor forward trafficking | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 1209 | HGNC ID: HGNC:2087 | Ensembl Gene: ENSG00000104853 | OMIM ID: 604783 |
| Drug and gene relationship at DGIdb | |||
Expression of CLPTM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLPTM1 | 1209 | 211136_s_at | 0.2983 | 0.3780 | |
| GSE20347 | CLPTM1 | 1209 | 211136_s_at | -0.1556 | 0.4000 | |
| GSE23400 | CLPTM1 | 1209 | 211136_s_at | 0.0657 | 0.5182 | |
| GSE26886 | CLPTM1 | 1209 | 201640_x_at | 0.1909 | 0.1424 | |
| GSE29001 | CLPTM1 | 1209 | 201640_x_at | 0.0163 | 0.9603 | |
| GSE38129 | CLPTM1 | 1209 | 211136_s_at | 0.0662 | 0.6996 | |
| GSE45670 | CLPTM1 | 1209 | 201640_x_at | 0.1695 | 0.0493 | |
| GSE53622 | CLPTM1 | 1209 | 10494 | 0.1115 | 0.1226 | |
| GSE53624 | CLPTM1 | 1209 | 10494 | 0.1283 | 0.0188 | |
| GSE63941 | CLPTM1 | 1209 | 201640_x_at | 0.7508 | 0.0040 | |
| GSE77861 | CLPTM1 | 1209 | 201640_x_at | 0.0730 | 0.6757 | |
| GSE97050 | CLPTM1 | 1209 | A_23_P50241 | 0.5599 | 0.1403 | |
| SRP007169 | CLPTM1 | 1209 | RNAseq | -1.0664 | 0.0007 | |
| SRP008496 | CLPTM1 | 1209 | RNAseq | -1.2673 | 0.0000 | |
| SRP064894 | CLPTM1 | 1209 | RNAseq | 0.1764 | 0.3374 | |
| SRP133303 | CLPTM1 | 1209 | RNAseq | 0.4494 | 0.0874 | |
| SRP159526 | CLPTM1 | 1209 | RNAseq | 0.3510 | 0.0237 | |
| SRP193095 | CLPTM1 | 1209 | RNAseq | 0.0552 | 0.6889 | |
| SRP219564 | CLPTM1 | 1209 | RNAseq | 0.1200 | 0.6417 | |
| TCGA | CLPTM1 | 1209 | RNAseq | -0.0516 | 0.2044 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CLPTM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLPTM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLPTM1 | 1209 | 4 | 5 | 21 | |
| GSE20123 | CLPTM1 | 1209 | 4 | 4 | 22 | |
| GSE43470 | CLPTM1 | 1209 | 3 | 11 | 29 | |
| GSE46452 | CLPTM1 | 1209 | 45 | 1 | 13 | |
| GSE47630 | CLPTM1 | 1209 | 8 | 6 | 26 | |
| GSE54993 | CLPTM1 | 1209 | 17 | 4 | 49 | |
| GSE54994 | CLPTM1 | 1209 | 6 | 12 | 35 | |
| GSE60625 | CLPTM1 | 1209 | 9 | 0 | 2 | |
| GSE74703 | CLPTM1 | 1209 | 3 | 7 | 26 | |
| GSE74704 | CLPTM1 | 1209 | 4 | 2 | 14 | |
| TCGA | CLPTM1 | 1209 | 14 | 17 | 65 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of CLPTM1:
Generating mutation plots.
Highly correlated genes for CLPTM1:
Showing top 20/554 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLPTM1 | FOXRED2 | 0.731596 | 4 | 0 | 4 |
| CLPTM1 | RPL8 | 0.724389 | 3 | 0 | 3 |
| CLPTM1 | XPNPEP1 | 0.718813 | 3 | 0 | 3 |
| CLPTM1 | FANCD2 | 0.714805 | 3 | 0 | 3 |
| CLPTM1 | MRPL38 | 0.709049 | 4 | 0 | 4 |
| CLPTM1 | SLC9A1 | 0.703729 | 6 | 0 | 5 |
| CLPTM1 | DNAJC9 | 0.694647 | 3 | 0 | 3 |
| CLPTM1 | MRPL3 | 0.690466 | 3 | 0 | 3 |
| CLPTM1 | INO80B | 0.68451 | 6 | 0 | 5 |
| CLPTM1 | DNA2 | 0.683436 | 3 | 0 | 3 |
| CLPTM1 | HGS | 0.683185 | 4 | 0 | 4 |
| CLPTM1 | NT5DC2 | 0.681685 | 4 | 0 | 3 |
| CLPTM1 | DERL1 | 0.680685 | 4 | 0 | 3 |
| CLPTM1 | AKT1S1 | 0.67582 | 7 | 0 | 7 |
| CLPTM1 | NRL | 0.673478 | 3 | 0 | 3 |
| CLPTM1 | OGFOD2 | 0.672496 | 5 | 0 | 4 |
| CLPTM1 | NOP2 | 0.669846 | 4 | 0 | 3 |
| CLPTM1 | FKBP4 | 0.669283 | 4 | 0 | 3 |
| CLPTM1 | FRS3 | 0.669105 | 3 | 0 | 3 |
| CLPTM1 | KDM5C | 0.667711 | 6 | 0 | 6 |
For details and further investigation, click here
