| Full name: formyl peptide receptor 3 | Alias Symbol: FPRH1|FMLPY|RMLP-R-I | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 2359 | HGNC ID: HGNC:3828 | Ensembl Gene: ENSG00000187474 | OMIM ID: 136539 |
| Drug and gene relationship at DGIdb | |||
FPR3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05150 | Staphylococcus aureus infection |
Expression of FPR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FPR3 | 2359 | 230422_at | 0.5959 | 0.6176 | |
| GSE20347 | FPR3 | 2359 | 214560_at | 0.1107 | 0.1689 | |
| GSE23400 | FPR3 | 2359 | 214560_at | 0.0902 | 0.1118 | |
| GSE26886 | FPR3 | 2359 | 214560_at | 0.0797 | 0.5675 | |
| GSE29001 | FPR3 | 2359 | 214560_at | 0.0278 | 0.9133 | |
| GSE38129 | FPR3 | 2359 | 214560_at | 0.1053 | 0.1693 | |
| GSE45670 | FPR3 | 2359 | 230422_at | 0.0299 | 0.9583 | |
| GSE53622 | FPR3 | 2359 | 91307 | 0.8681 | 0.0000 | |
| GSE53624 | FPR3 | 2359 | 91307 | 1.1484 | 0.0000 | |
| GSE63941 | FPR3 | 2359 | 214560_at | 0.2509 | 0.0918 | |
| GSE77861 | FPR3 | 2359 | 230422_at | 0.1534 | 0.2539 | |
| GSE97050 | FPR3 | 2359 | A_33_P3247042 | 0.7149 | 0.2261 | |
| SRP007169 | FPR3 | 2359 | RNAseq | 3.4700 | 0.0000 | |
| SRP008496 | FPR3 | 2359 | RNAseq | 2.3771 | 0.0000 | |
| SRP064894 | FPR3 | 2359 | RNAseq | 1.3577 | 0.0000 | |
| SRP133303 | FPR3 | 2359 | RNAseq | 1.2792 | 0.0000 | |
| SRP159526 | FPR3 | 2359 | RNAseq | 1.1060 | 0.2082 | |
| SRP193095 | FPR3 | 2359 | RNAseq | 1.2010 | 0.0000 | |
| SRP219564 | FPR3 | 2359 | RNAseq | 2.2026 | 0.0059 | |
| TCGA | FPR3 | 2359 | RNAseq | 0.4466 | 0.0041 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by FPR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FPR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FPR3 | 2359 | 3 | 4 | 23 | |
| GSE20123 | FPR3 | 2359 | 3 | 3 | 24 | |
| GSE43470 | FPR3 | 2359 | 3 | 12 | 28 | |
| GSE46452 | FPR3 | 2359 | 45 | 1 | 13 | |
| GSE47630 | FPR3 | 2359 | 10 | 6 | 24 | |
| GSE54993 | FPR3 | 2359 | 17 | 4 | 49 | |
| GSE54994 | FPR3 | 2359 | 4 | 14 | 35 | |
| GSE60625 | FPR3 | 2359 | 9 | 0 | 2 | |
| GSE74703 | FPR3 | 2359 | 3 | 8 | 25 | |
| GSE74704 | FPR3 | 2359 | 3 | 1 | 16 | |
| TCGA | FPR3 | 2359 | 14 | 20 | 62 |
Total number of gains: 114; Total number of losses: 73; Total Number of normals: 301.
Somatic mutations of FPR3:
Generating mutation plots.
Highly correlated genes for FPR3:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FPR3 | C1QB | 0.761672 | 8 | 0 | 7 |
| FPR3 | CYBB | 0.755772 | 9 | 0 | 8 |
| FPR3 | C1QC | 0.752928 | 7 | 0 | 6 |
| FPR3 | SLC7A7 | 0.741117 | 10 | 0 | 9 |
| FPR3 | PLXNC1 | 0.740947 | 6 | 0 | 5 |
| FPR3 | CD163 | 0.73571 | 8 | 0 | 8 |
| FPR3 | TMEM150B | 0.735594 | 3 | 0 | 3 |
| FPR3 | TLR8 | 0.719639 | 6 | 0 | 6 |
| FPR3 | FCER1G | 0.716502 | 8 | 0 | 6 |
| FPR3 | PSMB8-AS1 | 0.712124 | 4 | 0 | 4 |
| FPR3 | SLAMF8 | 0.709272 | 9 | 0 | 7 |
| FPR3 | PTPRJ | 0.70083 | 6 | 0 | 6 |
| FPR3 | CD14 | 0.692952 | 8 | 0 | 6 |
| FPR3 | MPEG1 | 0.689991 | 5 | 0 | 5 |
| FPR3 | SIGLEC12 | 0.689862 | 3 | 0 | 3 |
| FPR3 | ITGB2 | 0.689183 | 8 | 0 | 6 |
| FPR3 | HLA-DQA1 | 0.687493 | 6 | 0 | 6 |
| FPR3 | CMKLR1 | 0.687393 | 8 | 0 | 7 |
| FPR3 | C1QA | 0.687229 | 8 | 0 | 6 |
| FPR3 | TIGIT | 0.682201 | 4 | 0 | 4 |
For details and further investigation, click here
