| Full name: CKLF like MARVEL transmembrane domain containing 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p22.3 | ||
| Entrez ID: 152189 | HGNC ID: HGNC:19179 | Ensembl Gene: ENSG00000170293 | OMIM ID: 607891 |
| Drug and gene relationship at DGIdb | |||
Expression of CMTM8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMTM8 | 152189 | 235099_at | 0.4497 | 0.3228 | |
| GSE26886 | CMTM8 | 152189 | 235099_at | 0.9217 | 0.0015 | |
| GSE45670 | CMTM8 | 152189 | 235099_at | -0.1440 | 0.6469 | |
| GSE53622 | CMTM8 | 152189 | 36623 | 0.3252 | 0.0687 | |
| GSE53624 | CMTM8 | 152189 | 36623 | 0.6460 | 0.0000 | |
| GSE63941 | CMTM8 | 152189 | 235099_at | 1.1806 | 0.1086 | |
| GSE77861 | CMTM8 | 152189 | 235099_at | 0.6251 | 0.0378 | |
| SRP064894 | CMTM8 | 152189 | RNAseq | -0.0589 | 0.8478 | |
| SRP133303 | CMTM8 | 152189 | RNAseq | 0.0045 | 0.9895 | |
| SRP159526 | CMTM8 | 152189 | RNAseq | 0.9935 | 0.0108 | |
| SRP219564 | CMTM8 | 152189 | RNAseq | 0.1953 | 0.5896 | |
| TCGA | CMTM8 | 152189 | RNAseq | -0.3733 | 0.0107 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CMTM8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CMTM8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMTM8 | 152189 | 0 | 18 | 12 | |
| GSE20123 | CMTM8 | 152189 | 0 | 18 | 12 | |
| GSE43470 | CMTM8 | 152189 | 1 | 20 | 22 | |
| GSE46452 | CMTM8 | 152189 | 2 | 17 | 40 | |
| GSE47630 | CMTM8 | 152189 | 1 | 25 | 14 | |
| GSE54993 | CMTM8 | 152189 | 6 | 3 | 61 | |
| GSE54994 | CMTM8 | 152189 | 1 | 32 | 20 | |
| GSE60625 | CMTM8 | 152189 | 5 | 0 | 6 | |
| GSE74703 | CMTM8 | 152189 | 1 | 17 | 18 | |
| GSE74704 | CMTM8 | 152189 | 0 | 12 | 8 | |
| TCGA | CMTM8 | 152189 | 1 | 69 | 26 |
Total number of gains: 18; Total number of losses: 231; Total Number of normals: 239.
Somatic mutations of CMTM8:
Generating mutation plots.
Highly correlated genes for CMTM8:
Showing top 20/180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMTM8 | CBLB | 0.732331 | 3 | 0 | 3 |
| CMTM8 | SRRT | 0.713338 | 3 | 0 | 3 |
| CMTM8 | IRF2BP2 | 0.702529 | 3 | 0 | 3 |
| CMTM8 | SF3B2 | 0.694748 | 3 | 0 | 3 |
| CMTM8 | TAF5L | 0.686638 | 3 | 0 | 3 |
| CMTM8 | F11R | 0.677036 | 3 | 0 | 3 |
| CMTM8 | CHD4 | 0.672317 | 3 | 0 | 3 |
| CMTM8 | MARK1 | 0.670759 | 3 | 0 | 3 |
| CMTM8 | TRAF5 | 0.668885 | 3 | 0 | 3 |
| CMTM8 | TRRAP | 0.667337 | 4 | 0 | 3 |
| CMTM8 | AP2B1 | 0.66659 | 4 | 0 | 3 |
| CMTM8 | SOGA1 | 0.665204 | 4 | 0 | 3 |
| CMTM8 | BAZ2A | 0.660602 | 3 | 0 | 3 |
| CMTM8 | FANCL | 0.658173 | 3 | 0 | 3 |
| CMTM8 | LINC00467 | 0.65505 | 3 | 0 | 3 |
| CMTM8 | RAVER1 | 0.653499 | 4 | 0 | 3 |
| CMTM8 | CPSF7 | 0.648588 | 4 | 0 | 4 |
| CMTM8 | PAN2 | 0.64633 | 3 | 0 | 3 |
| CMTM8 | POLRMT | 0.635635 | 4 | 0 | 3 |
| CMTM8 | HS1BP3 | 0.630944 | 3 | 0 | 3 |
For details and further investigation, click here
