| Full name: melanoregulin | Alias Symbol: FLJ10116|DSU|WDT2 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 55686 | HGNC ID: HGNC:25478 | Ensembl Gene: ENSG00000118242 | OMIM ID: 609207 |
| Drug and gene relationship at DGIdb | |||
Expression of MREG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MREG | 55686 | 219648_at | -0.1033 | 0.9466 | |
| GSE20347 | MREG | 55686 | 219648_at | -1.4025 | 0.0000 | |
| GSE23400 | MREG | 55686 | 219648_at | -0.8232 | 0.0000 | |
| GSE26886 | MREG | 55686 | 219648_at | -2.2354 | 0.0000 | |
| GSE29001 | MREG | 55686 | 219648_at | -0.8665 | 0.0092 | |
| GSE38129 | MREG | 55686 | 219648_at | -0.3742 | 0.4235 | |
| GSE45670 | MREG | 55686 | 219648_at | -0.1566 | 0.5162 | |
| GSE53622 | MREG | 55686 | 44213 | -0.6663 | 0.0059 | |
| GSE53624 | MREG | 55686 | 44213 | -1.2712 | 0.0000 | |
| GSE63941 | MREG | 55686 | 219648_at | 2.6127 | 0.0000 | |
| GSE77861 | MREG | 55686 | 219648_at | -0.6753 | 0.0529 | |
| GSE97050 | MREG | 55686 | A_24_P351283 | 0.6308 | 0.2785 | |
| SRP007169 | MREG | 55686 | RNAseq | -1.1571 | 0.0608 | |
| SRP008496 | MREG | 55686 | RNAseq | -1.1545 | 0.0049 | |
| SRP064894 | MREG | 55686 | RNAseq | -1.3610 | 0.0000 | |
| SRP133303 | MREG | 55686 | RNAseq | -0.9454 | 0.0000 | |
| SRP159526 | MREG | 55686 | RNAseq | -0.9800 | 0.0264 | |
| SRP193095 | MREG | 55686 | RNAseq | -1.2040 | 0.0000 | |
| SRP219564 | MREG | 55686 | RNAseq | -1.9513 | 0.0318 | |
| TCGA | MREG | 55686 | RNAseq | 0.5683 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by MREG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MREG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MREG | 55686 | 1 | 13 | 16 | |
| GSE20123 | MREG | 55686 | 1 | 13 | 16 | |
| GSE43470 | MREG | 55686 | 0 | 7 | 36 | |
| GSE46452 | MREG | 55686 | 0 | 5 | 54 | |
| GSE47630 | MREG | 55686 | 4 | 5 | 31 | |
| GSE54993 | MREG | 55686 | 0 | 3 | 67 | |
| GSE54994 | MREG | 55686 | 8 | 9 | 36 | |
| GSE60625 | MREG | 55686 | 0 | 3 | 8 | |
| GSE74703 | MREG | 55686 | 0 | 6 | 30 | |
| GSE74704 | MREG | 55686 | 1 | 7 | 12 | |
| TCGA | MREG | 55686 | 11 | 28 | 57 |
Total number of gains: 26; Total number of losses: 99; Total Number of normals: 363.
Somatic mutations of MREG:
Generating mutation plots.
Highly correlated genes for MREG:
Showing top 20/1407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MREG | SORD | 0.781442 | 4 | 0 | 4 |
| MREG | NIPAL1 | 0.772968 | 3 | 0 | 3 |
| MREG | AP1S3 | 0.772626 | 5 | 0 | 5 |
| MREG | RTN4IP1 | 0.766643 | 3 | 0 | 3 |
| MREG | PGM2 | 0.759824 | 7 | 0 | 6 |
| MREG | MPZL3 | 0.75858 | 8 | 0 | 7 |
| MREG | LTA4H | 0.748617 | 3 | 0 | 3 |
| MREG | SAMD9 | 0.746139 | 9 | 0 | 9 |
| MREG | CERS3 | 0.745301 | 7 | 0 | 6 |
| MREG | TGM1 | 0.745155 | 11 | 0 | 10 |
| MREG | FAM83G | 0.743996 | 4 | 0 | 3 |
| MREG | BAIAP2L1 | 0.741848 | 4 | 0 | 4 |
| MREG | CDS1 | 0.741373 | 12 | 0 | 10 |
| MREG | JUP | 0.736759 | 10 | 0 | 9 |
| MREG | RASSF5 | 0.73533 | 6 | 0 | 6 |
| MREG | RAB25 | 0.733954 | 12 | 0 | 11 |
| MREG | ARNTL2 | 0.732508 | 10 | 0 | 9 |
| MREG | HPSE | 0.732365 | 11 | 0 | 11 |
| MREG | HUS1 | 0.732174 | 3 | 0 | 3 |
| MREG | GRPEL2 | 0.729841 | 7 | 0 | 6 |
For details and further investigation, click here
