| Full name: CCR4-NOT transcription complex subunit 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p22 | ||
| Entrez ID: 29883 | HGNC ID: HGNC:14101 | Ensembl Gene: ENSG00000198791 | OMIM ID: 604913 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CNOT7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNOT7 | 29883 | 225053_at | 0.2881 | 0.4172 | |
| GSE20347 | CNOT7 | 29883 | 218250_s_at | 0.4719 | 0.0104 | |
| GSE23400 | CNOT7 | 29883 | 218250_s_at | 0.3917 | 0.0001 | |
| GSE26886 | CNOT7 | 29883 | 225053_at | -0.0011 | 0.9954 | |
| GSE29001 | CNOT7 | 29883 | 218250_s_at | 0.2607 | 0.3988 | |
| GSE38129 | CNOT7 | 29883 | 218250_s_at | 0.3271 | 0.0431 | |
| GSE45670 | CNOT7 | 29883 | 225053_at | -0.0447 | 0.7778 | |
| GSE53622 | CNOT7 | 29883 | 47066 | -0.1861 | 0.0199 | |
| GSE53624 | CNOT7 | 29883 | 47066 | -0.0893 | 0.1853 | |
| GSE63941 | CNOT7 | 29883 | 225053_at | 0.2359 | 0.5867 | |
| GSE77861 | CNOT7 | 29883 | 225053_at | -0.0945 | 0.8023 | |
| GSE97050 | CNOT7 | 29883 | A_32_P141262 | -0.1493 | 0.5525 | |
| SRP007169 | CNOT7 | 29883 | RNAseq | 0.0860 | 0.8170 | |
| SRP008496 | CNOT7 | 29883 | RNAseq | -0.1140 | 0.5998 | |
| SRP064894 | CNOT7 | 29883 | RNAseq | -0.0691 | 0.7116 | |
| SRP133303 | CNOT7 | 29883 | RNAseq | -0.0228 | 0.9100 | |
| SRP159526 | CNOT7 | 29883 | RNAseq | 0.0081 | 0.9692 | |
| SRP193095 | CNOT7 | 29883 | RNAseq | -0.3159 | 0.0242 | |
| SRP219564 | CNOT7 | 29883 | RNAseq | -0.2004 | 0.4752 | |
| TCGA | CNOT7 | 29883 | RNAseq | 0.0527 | 0.2742 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNOT7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNOT7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNOT7 | 29883 | 3 | 11 | 16 | |
| GSE20123 | CNOT7 | 29883 | 4 | 11 | 15 | |
| GSE43470 | CNOT7 | 29883 | 4 | 8 | 31 | |
| GSE46452 | CNOT7 | 29883 | 14 | 13 | 32 | |
| GSE47630 | CNOT7 | 29883 | 10 | 8 | 22 | |
| GSE54993 | CNOT7 | 29883 | 2 | 14 | 54 | |
| GSE54994 | CNOT7 | 29883 | 8 | 18 | 27 | |
| GSE60625 | CNOT7 | 29883 | 3 | 0 | 8 | |
| GSE74703 | CNOT7 | 29883 | 4 | 7 | 25 | |
| GSE74704 | CNOT7 | 29883 | 3 | 7 | 10 | |
| TCGA | CNOT7 | 29883 | 14 | 40 | 42 |
Total number of gains: 69; Total number of losses: 137; Total Number of normals: 282.
Somatic mutations of CNOT7:
Generating mutation plots.
Highly correlated genes for CNOT7:
Showing top 20/584 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNOT7 | WDR36 | 0.759198 | 3 | 0 | 3 |
| CNOT7 | MTFMT | 0.75124 | 3 | 0 | 3 |
| CNOT7 | NDUFA10 | 0.749992 | 3 | 0 | 3 |
| CNOT7 | SGMS1 | 0.747081 | 3 | 0 | 3 |
| CNOT7 | MRPL39 | 0.729533 | 3 | 0 | 3 |
| CNOT7 | XRCC6 | 0.729075 | 4 | 0 | 4 |
| CNOT7 | MRPL47 | 0.728637 | 3 | 0 | 3 |
| CNOT7 | FOPNL | 0.723605 | 3 | 0 | 3 |
| CNOT7 | MEF2A | 0.723056 | 3 | 0 | 3 |
| CNOT7 | API5 | 0.720105 | 3 | 0 | 3 |
| CNOT7 | MYO5A | 0.710918 | 3 | 0 | 3 |
| CNOT7 | ZDHHC7 | 0.710758 | 3 | 0 | 3 |
| CNOT7 | ATIC | 0.710351 | 5 | 0 | 4 |
| CNOT7 | ZNF776 | 0.70812 | 3 | 0 | 3 |
| CNOT7 | MRPL37 | 0.705415 | 3 | 0 | 3 |
| CNOT7 | PLEKHB2 | 0.704717 | 4 | 0 | 4 |
| CNOT7 | IFFO2 | 0.703012 | 3 | 0 | 3 |
| CNOT7 | HMG20A | 0.700416 | 5 | 0 | 5 |
| CNOT7 | FGGY | 0.69477 | 3 | 0 | 3 |
| CNOT7 | DUT | 0.694295 | 4 | 0 | 4 |
For details and further investigation, click here
