| Full name: collagen type XVII alpha 1 chain | Alias Symbol: BP180 | ||
| Type: protein-coding gene | Cytoband: 10q25.1 | ||
| Entrez ID: 1308 | HGNC ID: HGNC:2194 | Ensembl Gene: ENSG00000065618 | OMIM ID: 113811 |
| Drug and gene relationship at DGIdb | |||
Expression of COL17A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL17A1 | 1308 | 204636_at | 0.7326 | 0.6638 | |
| GSE20347 | COL17A1 | 1308 | 204636_at | 0.0601 | 0.8599 | |
| GSE23400 | COL17A1 | 1308 | 204636_at | 0.8901 | 0.0001 | |
| GSE26886 | COL17A1 | 1308 | 204636_at | 1.1924 | 0.0032 | |
| GSE29001 | COL17A1 | 1308 | 204636_at | 0.7121 | 0.1059 | |
| GSE38129 | COL17A1 | 1308 | 204636_at | 0.6965 | 0.0310 | |
| GSE45670 | COL17A1 | 1308 | 204636_at | 1.1176 | 0.0553 | |
| GSE53622 | COL17A1 | 1308 | 93818 | 0.6777 | 0.0111 | |
| GSE53624 | COL17A1 | 1308 | 93818 | 0.4908 | 0.0095 | |
| GSE63941 | COL17A1 | 1308 | 204636_at | 2.7974 | 0.0377 | |
| GSE77861 | COL17A1 | 1308 | 204636_at | 0.0838 | 0.9199 | |
| GSE97050 | COL17A1 | 1308 | A_23_P501010 | 1.2338 | 0.2844 | |
| SRP007169 | COL17A1 | 1308 | RNAseq | -0.4892 | 0.3038 | |
| SRP008496 | COL17A1 | 1308 | RNAseq | 0.5529 | 0.1494 | |
| SRP064894 | COL17A1 | 1308 | RNAseq | 0.9972 | 0.0350 | |
| SRP133303 | COL17A1 | 1308 | RNAseq | 1.1267 | 0.0039 | |
| SRP193095 | COL17A1 | 1308 | RNAseq | 1.0709 | 0.0007 | |
| SRP219564 | COL17A1 | 1308 | RNAseq | 1.0939 | 0.4125 | |
| TCGA | COL17A1 | 1308 | RNAseq | 0.7372 | 0.0004 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by COL17A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL17A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL17A1 | 1308 | 1 | 9 | 20 | |
| GSE20123 | COL17A1 | 1308 | 1 | 8 | 21 | |
| GSE43470 | COL17A1 | 1308 | 0 | 7 | 36 | |
| GSE46452 | COL17A1 | 1308 | 0 | 11 | 48 | |
| GSE47630 | COL17A1 | 1308 | 2 | 14 | 24 | |
| GSE54993 | COL17A1 | 1308 | 8 | 0 | 62 | |
| GSE54994 | COL17A1 | 1308 | 1 | 10 | 42 | |
| GSE60625 | COL17A1 | 1308 | 0 | 0 | 11 | |
| GSE74703 | COL17A1 | 1308 | 0 | 5 | 31 | |
| GSE74704 | COL17A1 | 1308 | 0 | 4 | 16 | |
| TCGA | COL17A1 | 1308 | 6 | 28 | 62 |
Total number of gains: 19; Total number of losses: 96; Total Number of normals: 373.
Somatic mutations of COL17A1:
Generating mutation plots.
Highly correlated genes for COL17A1:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL17A1 | SF3A2 | 0.742148 | 3 | 0 | 3 |
| COL17A1 | YARS2 | 0.713494 | 3 | 0 | 3 |
| COL17A1 | RPS19 | 0.705815 | 3 | 0 | 3 |
| COL17A1 | FUT8 | 0.694129 | 3 | 0 | 3 |
| COL17A1 | SCAMP1 | 0.694097 | 3 | 0 | 3 |
| COL17A1 | MTX3 | 0.685755 | 3 | 0 | 3 |
| COL17A1 | EIF3E | 0.685692 | 3 | 0 | 3 |
| COL17A1 | GLRX5 | 0.684121 | 3 | 0 | 3 |
| COL17A1 | ALPK2 | 0.676752 | 3 | 0 | 3 |
| COL17A1 | PPWD1 | 0.670417 | 3 | 0 | 3 |
| COL17A1 | PCK2 | 0.666415 | 3 | 0 | 3 |
| COL17A1 | STON2 | 0.665911 | 8 | 0 | 7 |
| COL17A1 | PLEK2 | 0.657234 | 13 | 0 | 11 |
| COL17A1 | LAMB3 | 0.657001 | 11 | 0 | 11 |
| COL17A1 | ADTRP | 0.655454 | 3 | 0 | 3 |
| COL17A1 | KYNU | 0.649285 | 3 | 0 | 3 |
| COL17A1 | VAC14 | 0.646176 | 3 | 0 | 3 |
| COL17A1 | ZFP90 | 0.643299 | 3 | 0 | 3 |
| COL17A1 | NANOS1 | 0.643209 | 3 | 0 | 3 |
| COL17A1 | SYNPO | 0.642147 | 3 | 0 | 3 |
For details and further investigation, click here
