| Full name: fucosyltransferase 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q23.3 | ||
| Entrez ID: 2530 | HGNC ID: HGNC:4019 | Ensembl Gene: ENSG00000033170 | OMIM ID: 602589 |
| Drug and gene relationship at DGIdb | |||
Expression of FUT8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUT8 | 2530 | 203988_s_at | 0.5473 | 0.3118 | |
| GSE20347 | FUT8 | 2530 | 203988_s_at | 1.2407 | 0.0000 | |
| GSE23400 | FUT8 | 2530 | 203988_s_at | 0.5664 | 0.0000 | |
| GSE26886 | FUT8 | 2530 | 203988_s_at | 0.9146 | 0.0000 | |
| GSE29001 | FUT8 | 2530 | 203988_s_at | 0.7377 | 0.0283 | |
| GSE38129 | FUT8 | 2530 | 203988_s_at | 1.0435 | 0.0001 | |
| GSE45670 | FUT8 | 2530 | 203988_s_at | 0.3905 | 0.2305 | |
| GSE53622 | FUT8 | 2530 | 122065 | 0.8158 | 0.0000 | |
| GSE53624 | FUT8 | 2530 | 122065 | 0.7942 | 0.0000 | |
| GSE63941 | FUT8 | 2530 | 203988_s_at | -0.3051 | 0.7480 | |
| GSE77861 | FUT8 | 2530 | 1554930_a_at | 0.1810 | 0.2573 | |
| GSE97050 | FUT8 | 2530 | A_23_P313632 | 0.6585 | 0.1150 | |
| SRP007169 | FUT8 | 2530 | RNAseq | 2.2828 | 0.0003 | |
| SRP008496 | FUT8 | 2530 | RNAseq | 2.1910 | 0.0000 | |
| SRP064894 | FUT8 | 2530 | RNAseq | 0.9376 | 0.0000 | |
| SRP133303 | FUT8 | 2530 | RNAseq | 0.9369 | 0.0000 | |
| SRP159526 | FUT8 | 2530 | RNAseq | 1.0075 | 0.0003 | |
| SRP193095 | FUT8 | 2530 | RNAseq | 0.1454 | 0.6933 | |
| SRP219564 | FUT8 | 2530 | RNAseq | 1.1983 | 0.0058 | |
| TCGA | FUT8 | 2530 | RNAseq | -0.3914 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by FUT8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FUT8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUT8 | 2530 | 7 | 3 | 20 | |
| GSE20123 | FUT8 | 2530 | 7 | 3 | 20 | |
| GSE43470 | FUT8 | 2530 | 7 | 3 | 33 | |
| GSE46452 | FUT8 | 2530 | 16 | 3 | 40 | |
| GSE47630 | FUT8 | 2530 | 11 | 9 | 20 | |
| GSE54993 | FUT8 | 2530 | 3 | 9 | 58 | |
| GSE54994 | FUT8 | 2530 | 18 | 5 | 30 | |
| GSE60625 | FUT8 | 2530 | 0 | 2 | 9 | |
| GSE74703 | FUT8 | 2530 | 6 | 3 | 27 | |
| GSE74704 | FUT8 | 2530 | 3 | 2 | 15 | |
| TCGA | FUT8 | 2530 | 32 | 14 | 50 |
Total number of gains: 110; Total number of losses: 56; Total Number of normals: 322.
Somatic mutations of FUT8:
Generating mutation plots.
Highly correlated genes for FUT8:
Showing top 20/1609 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUT8 | IMMP1L | 0.730877 | 3 | 0 | 3 |
| FUT8 | TRAM2 | 0.73012 | 12 | 0 | 11 |
| FUT8 | NFKB1 | 0.728974 | 3 | 0 | 3 |
| FUT8 | CDK14 | 0.708885 | 9 | 0 | 9 |
| FUT8 | TMEM263 | 0.70289 | 6 | 0 | 5 |
| FUT8 | G2E3 | 0.699931 | 5 | 0 | 4 |
| FUT8 | GAPT | 0.698627 | 3 | 0 | 3 |
| FUT8 | PLCG1 | 0.695729 | 5 | 0 | 5 |
| FUT8 | TMEM223 | 0.695656 | 4 | 0 | 3 |
| FUT8 | COL17A1 | 0.694129 | 3 | 0 | 3 |
| FUT8 | SSBP4 | 0.69164 | 4 | 0 | 3 |
| FUT8 | PPP1R35 | 0.691341 | 4 | 0 | 4 |
| FUT8 | MED30 | 0.69112 | 7 | 0 | 6 |
| FUT8 | FANCM | 0.689361 | 4 | 0 | 3 |
| FUT8 | TEAD2 | 0.685885 | 4 | 0 | 4 |
| FUT8 | GAPDH | 0.685145 | 4 | 0 | 3 |
| FUT8 | TNFSF4 | 0.684804 | 8 | 0 | 8 |
| FUT8 | CDH11 | 0.684366 | 12 | 0 | 11 |
| FUT8 | BCL2L11 | 0.684041 | 4 | 0 | 3 |
| FUT8 | MARCKSL1 | 0.68388 | 11 | 0 | 11 |
For details and further investigation, click here
