| Full name: GTP binding protein overexpressed in skeletal muscle | Alias Symbol: KIR | ||
| Type: protein-coding gene | Cytoband: 8q22.1 | ||
| Entrez ID: 2669 | HGNC ID: HGNC:4234 | Ensembl Gene: ENSG00000164949 | OMIM ID: 600164 |
Expression of GEM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GEM | 2669 | 204472_at | -0.6952 | 0.5897 | |
| GSE20347 | GEM | 2669 | 204472_at | -0.8638 | 0.0440 | |
| GSE23400 | GEM | 2669 | 204472_at | -0.1132 | 0.6079 | |
| GSE26886 | GEM | 2669 | 204472_at | 1.7471 | 0.0014 | |
| GSE29001 | GEM | 2669 | 204472_at | -1.1402 | 0.0715 | |
| GSE38129 | GEM | 2669 | 204472_at | -0.7953 | 0.0202 | |
| GSE45670 | GEM | 2669 | 204472_at | -2.1195 | 0.0001 | |
| GSE53622 | GEM | 2669 | 9803 | -0.7222 | 0.0000 | |
| GSE53624 | GEM | 2669 | 9803 | -0.8908 | 0.0000 | |
| GSE63941 | GEM | 2669 | 204472_at | -2.7708 | 0.0611 | |
| GSE77861 | GEM | 2669 | 204472_at | 0.4659 | 0.5946 | |
| GSE97050 | GEM | 2669 | A_23_P257043 | -0.3438 | 0.4979 | |
| SRP007169 | GEM | 2669 | RNAseq | -1.2700 | 0.0422 | |
| SRP008496 | GEM | 2669 | RNAseq | -0.1108 | 0.8823 | |
| SRP064894 | GEM | 2669 | RNAseq | 0.0979 | 0.8133 | |
| SRP133303 | GEM | 2669 | RNAseq | -0.2517 | 0.5549 | |
| SRP159526 | GEM | 2669 | RNAseq | 0.5389 | 0.2390 | |
| SRP193095 | GEM | 2669 | RNAseq | 0.1120 | 0.7575 | |
| SRP219564 | GEM | 2669 | RNAseq | -0.8336 | 0.3841 | |
| TCGA | GEM | 2669 | RNAseq | -0.3723 | 0.0114 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by GEM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GEM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GEM | 2669 | 16 | 0 | 14 | |
| GSE20123 | GEM | 2669 | 17 | 0 | 13 | |
| GSE43470 | GEM | 2669 | 21 | 1 | 21 | |
| GSE46452 | GEM | 2669 | 22 | 0 | 37 | |
| GSE47630 | GEM | 2669 | 24 | 0 | 16 | |
| GSE54993 | GEM | 2669 | 0 | 20 | 50 | |
| GSE54994 | GEM | 2669 | 34 | 1 | 18 | |
| GSE60625 | GEM | 2669 | 0 | 4 | 7 | |
| GSE74703 | GEM | 2669 | 18 | 1 | 17 | |
| GSE74704 | GEM | 2669 | 12 | 0 | 8 | |
| TCGA | GEM | 2669 | 56 | 1 | 39 |
Total number of gains: 220; Total number of losses: 28; Total Number of normals: 240.
Somatic mutations of GEM:
Generating mutation plots.
Highly correlated genes for GEM:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GEM | C11orf96 | 0.805832 | 5 | 0 | 5 |
| GEM | FBN1 | 0.737308 | 5 | 0 | 5 |
| GEM | COL4A5 | 0.727543 | 3 | 0 | 3 |
| GEM | RILPL1 | 0.726533 | 3 | 0 | 3 |
| GEM | SLC39A13 | 0.726214 | 3 | 0 | 3 |
| GEM | CFL2 | 0.71114 | 5 | 0 | 5 |
| GEM | MRGPRF | 0.70712 | 6 | 0 | 5 |
| GEM | GLG1 | 0.702921 | 3 | 0 | 3 |
| GEM | SCCPDH | 0.692073 | 3 | 0 | 3 |
| GEM | LCA5 | 0.690796 | 4 | 0 | 4 |
| GEM | ZEB1 | 0.689099 | 3 | 0 | 3 |
| GEM | GRAMD1A | 0.682395 | 3 | 0 | 3 |
| GEM | RHOJ | 0.682023 | 4 | 0 | 4 |
| GEM | LRP3 | 0.679695 | 3 | 0 | 3 |
| GEM | TCTN1 | 0.677906 | 3 | 0 | 3 |
| GEM | PIK3R3 | 0.675389 | 3 | 0 | 3 |
| GEM | PLEKHA3 | 0.673323 | 3 | 0 | 3 |
| GEM | MYL6B | 0.67028 | 3 | 0 | 3 |
| GEM | FIBIN | 0.669792 | 4 | 0 | 4 |
| GEM | NT5M | 0.665057 | 3 | 0 | 3 |
For details and further investigation, click here
