| Full name: NME/NM23 nucleoside diphosphate kinase 3 | Alias Symbol: DR-nm23|NM23-H3|NDPKC | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 4832 | HGNC ID: HGNC:7851 | Ensembl Gene: ENSG00000103024 | OMIM ID: 601817 |
| Drug and gene relationship at DGIdb | |||
Expression of NME3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NME3 | 4832 | 204862_s_at | 0.2204 | 0.5079 | |
| GSE20347 | NME3 | 4832 | 204862_s_at | 0.1548 | 0.3739 | |
| GSE23400 | NME3 | 4832 | 204862_s_at | 0.0815 | 0.3732 | |
| GSE26886 | NME3 | 4832 | 204862_s_at | 0.7721 | 0.0000 | |
| GSE29001 | NME3 | 4832 | 204862_s_at | 0.2141 | 0.6954 | |
| GSE38129 | NME3 | 4832 | 204862_s_at | 0.0327 | 0.8434 | |
| GSE45670 | NME3 | 4832 | 204862_s_at | 0.0158 | 0.9375 | |
| GSE53622 | NME3 | 4832 | 71100 | 0.1867 | 0.0067 | |
| GSE53624 | NME3 | 4832 | 71100 | 0.2618 | 0.0001 | |
| GSE63941 | NME3 | 4832 | 204862_s_at | -0.3262 | 0.7549 | |
| GSE77861 | NME3 | 4832 | 204862_s_at | 0.0845 | 0.6719 | |
| GSE97050 | NME3 | 4832 | A_23_P152115 | 0.0113 | 0.9739 | |
| SRP007169 | NME3 | 4832 | RNAseq | 0.2079 | 0.5918 | |
| SRP008496 | NME3 | 4832 | RNAseq | 0.2490 | 0.4440 | |
| SRP064894 | NME3 | 4832 | RNAseq | -0.2739 | 0.4297 | |
| SRP133303 | NME3 | 4832 | RNAseq | -0.1310 | 0.6135 | |
| SRP159526 | NME3 | 4832 | RNAseq | 0.0234 | 0.9220 | |
| SRP193095 | NME3 | 4832 | RNAseq | 0.2073 | 0.1771 | |
| SRP219564 | NME3 | 4832 | RNAseq | 0.0028 | 0.9952 | |
| TCGA | NME3 | 4832 | RNAseq | -0.0147 | 0.8808 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NME3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NME3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NME3 | 4832 | 5 | 5 | 20 | |
| GSE20123 | NME3 | 4832 | 5 | 4 | 21 | |
| GSE43470 | NME3 | 4832 | 4 | 7 | 32 | |
| GSE46452 | NME3 | 4832 | 38 | 1 | 20 | |
| GSE47630 | NME3 | 4832 | 13 | 6 | 21 | |
| GSE54993 | NME3 | 4832 | 3 | 5 | 62 | |
| GSE54994 | NME3 | 4832 | 6 | 8 | 39 | |
| GSE60625 | NME3 | 4832 | 4 | 0 | 7 | |
| GSE74703 | NME3 | 4832 | 4 | 5 | 27 | |
| GSE74704 | NME3 | 4832 | 3 | 2 | 15 | |
| TCGA | NME3 | 4832 | 19 | 14 | 63 |
Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.
Somatic mutations of NME3:
Generating mutation plots.
Highly correlated genes for NME3:
Showing top 20/85 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NME3 | NOB1 | 0.715919 | 3 | 0 | 3 |
| NME3 | SHISA7 | 0.665015 | 3 | 0 | 3 |
| NME3 | COL9A3 | 0.664788 | 3 | 0 | 3 |
| NME3 | OSGIN1 | 0.661386 | 3 | 0 | 3 |
| NME3 | BLOC1S3 | 0.659086 | 3 | 0 | 3 |
| NME3 | HSD17B14 | 0.646815 | 4 | 0 | 4 |
| NME3 | IFT43 | 0.634815 | 4 | 0 | 3 |
| NME3 | CRABP1 | 0.634372 | 3 | 0 | 3 |
| NME3 | PACSIN2 | 0.633121 | 4 | 0 | 4 |
| NME3 | SHISA4 | 0.61708 | 3 | 0 | 3 |
| NME3 | RHPN1 | 0.613173 | 3 | 0 | 3 |
| NME3 | TATDN3 | 0.610258 | 3 | 0 | 3 |
| NME3 | DNLZ | 0.602871 | 3 | 0 | 3 |
| NME3 | DUS2 | 0.592662 | 4 | 0 | 3 |
| NME3 | TMEM59L | 0.587909 | 3 | 0 | 3 |
| NME3 | SUPT6H | 0.587422 | 5 | 0 | 4 |
| NME3 | C12orf10 | 0.585773 | 4 | 0 | 3 |
| NME3 | PMPCA | 0.585233 | 4 | 0 | 4 |
| NME3 | CHGB | 0.582014 | 3 | 0 | 3 |
| NME3 | DFFB | 0.581159 | 4 | 0 | 3 |
For details and further investigation, click here
