| Full name: ectonucleoside triphosphate diphosphohydrolase 6 | Alias Symbol: NTPDase-6|dJ738P15.3 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 955 | HGNC ID: HGNC:3368 | Ensembl Gene: ENSG00000197586 | OMIM ID: 603160 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD6 | 955 | 201704_at | 1.0267 | 0.0308 | |
| GSE20347 | ENTPD6 | 955 | 201704_at | 0.6205 | 0.0003 | |
| GSE23400 | ENTPD6 | 955 | 201704_at | 0.6352 | 0.0000 | |
| GSE26886 | ENTPD6 | 955 | 201704_at | 0.0494 | 0.8084 | |
| GSE29001 | ENTPD6 | 955 | 201704_at | 0.6737 | 0.0665 | |
| GSE38129 | ENTPD6 | 955 | 201704_at | 0.7161 | 0.0000 | |
| GSE45670 | ENTPD6 | 955 | 201704_at | 0.3807 | 0.0063 | |
| GSE63941 | ENTPD6 | 955 | 201704_at | 0.6194 | 0.1645 | |
| GSE77861 | ENTPD6 | 955 | 201704_at | 0.2747 | 0.2463 | |
| GSE97050 | ENTPD6 | 955 | A_23_P79999 | 0.6294 | 0.1860 | |
| SRP007169 | ENTPD6 | 955 | RNAseq | 0.3359 | 0.3293 | |
| SRP008496 | ENTPD6 | 955 | RNAseq | 0.3093 | 0.2271 | |
| SRP064894 | ENTPD6 | 955 | RNAseq | 0.8644 | 0.0002 | |
| SRP133303 | ENTPD6 | 955 | RNAseq | 0.6614 | 0.0000 | |
| SRP159526 | ENTPD6 | 955 | RNAseq | 1.4170 | 0.0012 | |
| SRP193095 | ENTPD6 | 955 | RNAseq | 0.4510 | 0.0264 | |
| TCGA | ENTPD6 | 955 | RNAseq | -0.0540 | 0.4196 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ENTPD6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD6 | 955 | 12 | 2 | 16 | |
| GSE20123 | ENTPD6 | 955 | 12 | 2 | 16 | |
| GSE43470 | ENTPD6 | 955 | 11 | 1 | 31 | |
| GSE46452 | ENTPD6 | 955 | 27 | 1 | 31 | |
| GSE47630 | ENTPD6 | 955 | 17 | 4 | 19 | |
| GSE54993 | ENTPD6 | 955 | 0 | 17 | 53 | |
| GSE54994 | ENTPD6 | 955 | 27 | 1 | 25 | |
| GSE60625 | ENTPD6 | 955 | 0 | 0 | 11 | |
| GSE74703 | ENTPD6 | 955 | 10 | 1 | 25 | |
| GSE74704 | ENTPD6 | 955 | 7 | 1 | 12 | |
| TCGA | ENTPD6 | 955 | 44 | 9 | 43 |
Total number of gains: 167; Total number of losses: 39; Total Number of normals: 282.
Somatic mutations of ENTPD6:
Generating mutation plots.
Highly correlated genes for ENTPD6:
Showing top 20/560 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD6 | APMAP | 0.743082 | 7 | 0 | 6 |
| ENTPD6 | MEX3A | 0.742328 | 3 | 0 | 3 |
| ENTPD6 | RPN2 | 0.732064 | 6 | 0 | 6 |
| ENTPD6 | SNRPC | 0.723972 | 4 | 0 | 4 |
| ENTPD6 | OTX1 | 0.702353 | 3 | 0 | 3 |
| ENTPD6 | ZC3HC1 | 0.694668 | 3 | 0 | 3 |
| ENTPD6 | YRDC | 0.681447 | 4 | 0 | 4 |
| ENTPD6 | STAM-AS1 | 0.67912 | 3 | 0 | 3 |
| ENTPD6 | APEX1 | 0.677701 | 4 | 0 | 4 |
| ENTPD6 | YTHDF1 | 0.668352 | 7 | 0 | 7 |
| ENTPD6 | GINS1 | 0.663264 | 6 | 0 | 5 |
| ENTPD6 | ECT2 | 0.663015 | 6 | 0 | 6 |
| ENTPD6 | CPSF1 | 0.661211 | 3 | 0 | 3 |
| ENTPD6 | STMN1 | 0.660977 | 4 | 0 | 4 |
| ENTPD6 | TTI1 | 0.659765 | 8 | 0 | 7 |
| ENTPD6 | ZDHHC23 | 0.658684 | 4 | 0 | 4 |
| ENTPD6 | SH3BP4 | 0.658182 | 5 | 0 | 5 |
| ENTPD6 | NUP155 | 0.656247 | 5 | 0 | 4 |
| ENTPD6 | KLHDC7B | 0.654412 | 3 | 0 | 3 |
| ENTPD6 | TUBB | 0.652021 | 5 | 0 | 4 |
For details and further investigation, click here
