| Full name: collagen like tail subunit of asymmetric acetylcholinesterase | Alias Symbol: EAD | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 8292 | HGNC ID: HGNC:2226 | Ensembl Gene: ENSG00000206561 | OMIM ID: 603033 |
| Drug and gene relationship at DGIdb | |||
Expression of COLQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COLQ | 8292 | 206073_at | -0.1447 | 0.4459 | |
| GSE20347 | COLQ | 8292 | 206073_at | 0.0400 | 0.6622 | |
| GSE23400 | COLQ | 8292 | 206073_at | -0.1604 | 0.0000 | |
| GSE26886 | COLQ | 8292 | 206073_at | 0.0466 | 0.6698 | |
| GSE29001 | COLQ | 8292 | 206073_at | 0.0555 | 0.8115 | |
| GSE38129 | COLQ | 8292 | 206073_at | -0.1054 | 0.2167 | |
| GSE45670 | COLQ | 8292 | 206073_at | 0.0172 | 0.8671 | |
| GSE53622 | COLQ | 8292 | 17027 | -0.2277 | 0.1932 | |
| GSE53624 | COLQ | 8292 | 158839 | -0.4570 | 0.0001 | |
| GSE63941 | COLQ | 8292 | 206073_at | -0.1838 | 0.3731 | |
| GSE77861 | COLQ | 8292 | 206073_at | -0.1407 | 0.3013 | |
| SRP064894 | COLQ | 8292 | RNAseq | 0.6336 | 0.0630 | |
| SRP133303 | COLQ | 8292 | RNAseq | -0.3955 | 0.1691 | |
| SRP159526 | COLQ | 8292 | RNAseq | -0.1205 | 0.7985 | |
| SRP219564 | COLQ | 8292 | RNAseq | 0.6249 | 0.2025 | |
| TCGA | COLQ | 8292 | RNAseq | -0.6780 | 0.0061 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COLQ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COLQ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COLQ | 8292 | 2 | 19 | 9 | |
| GSE20123 | COLQ | 8292 | 2 | 19 | 9 | |
| GSE43470 | COLQ | 8292 | 0 | 21 | 22 | |
| GSE46452 | COLQ | 8292 | 2 | 17 | 40 | |
| GSE47630 | COLQ | 8292 | 2 | 23 | 15 | |
| GSE54993 | COLQ | 8292 | 6 | 1 | 63 | |
| GSE54994 | COLQ | 8292 | 1 | 32 | 20 | |
| GSE60625 | COLQ | 8292 | 5 | 0 | 6 | |
| GSE74703 | COLQ | 8292 | 0 | 17 | 19 | |
| GSE74704 | COLQ | 8292 | 1 | 13 | 6 | |
| TCGA | COLQ | 8292 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 230; Total Number of normals: 235.
Somatic mutations of COLQ:
Generating mutation plots.
Highly correlated genes for COLQ:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COLQ | CPA1 | 0.688924 | 3 | 0 | 3 |
| COLQ | PLCL1 | 0.625036 | 3 | 0 | 3 |
| COLQ | NFASC | 0.620165 | 3 | 0 | 3 |
| COLQ | IGSF9B | 0.594606 | 6 | 0 | 6 |
| COLQ | CLDND2 | 0.588131 | 3 | 0 | 3 |
| COLQ | MAGEB4 | 0.585862 | 3 | 0 | 3 |
| COLQ | KIAA1614 | 0.585806 | 4 | 0 | 3 |
| COLQ | CADM3 | 0.576729 | 7 | 0 | 6 |
| COLQ | ARHGEF15 | 0.561757 | 5 | 0 | 3 |
| COLQ | TTC16 | 0.558767 | 3 | 0 | 3 |
| COLQ | PRRT2 | 0.55663 | 4 | 0 | 3 |
| COLQ | LHCGR | 0.547795 | 4 | 0 | 3 |
| COLQ | FXYD1 | 0.547631 | 3 | 0 | 3 |
| COLQ | RXRG | 0.547399 | 5 | 0 | 3 |
| COLQ | NFATC4 | 0.543987 | 9 | 0 | 5 |
| COLQ | LDB3 | 0.543562 | 6 | 0 | 4 |
| COLQ | KLKB1 | 0.542068 | 7 | 0 | 4 |
| COLQ | NR2E3 | 0.541857 | 4 | 0 | 4 |
| COLQ | RDH8 | 0.540629 | 5 | 0 | 4 |
| COLQ | DHRS12 | 0.540152 | 3 | 0 | 3 |
For details and further investigation, click here
