NUP37

 

Full name: nucleoporin 37 Alias Symbol: MGC5585|FLJ22618
Type: protein-coding gene Cytoband: 12q23.2
Entrez ID: 79023 HGNC ID: HGNC:29929 Ensembl Gene: ENSG00000075188 OMIM ID: 609264
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NUP37:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUP37 79023 218622_at 0.2439 0.7463
GSE20347 NUP37 79023 218622_at 0.5550 0.0102
GSE23400 NUP37 79023 218622_at 0.8974 0.0000
GSE26886 NUP37 79023 218622_at 0.4689 0.0011
GSE29001 NUP37 79023 218622_at 0.8251 0.0856
GSE38129 NUP37 79023 218622_at 0.8651 0.0000
GSE45670 NUP37 79023 218622_at 0.5539 0.0002
GSE53622 NUP37 79023 39128 0.7918 0.0000
GSE53624 NUP37 79023 39128 0.8404 0.0000
GSE63941 NUP37 79023 218622_at 1.0346 0.0030
GSE77861 NUP37 79023 218622_at 0.4691 0.1420
GSE97050 NUP37 79023 A_23_P48099 0.5066 0.1389
SRP007169 NUP37 79023 RNAseq 0.8557 0.0400
SRP008496 NUP37 79023 RNAseq 0.6668 0.0086
SRP064894 NUP37 79023 RNAseq 0.4633 0.0012
SRP133303 NUP37 79023 RNAseq 0.5255 0.0110
SRP159526 NUP37 79023 RNAseq 0.4090 0.1189
SRP193095 NUP37 79023 RNAseq 0.1990 0.1719
SRP219564 NUP37 79023 RNAseq 0.1017 0.7578
TCGA NUP37 79023 RNAseq 0.4705 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by NUP37 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUP37:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUP37 79023 3 2 25
GSE20123 NUP37 79023 3 2 25
GSE43470 NUP37 79023 2 0 41
GSE46452 NUP37 79023 9 1 49
GSE47630 NUP37 79023 9 1 30
GSE54993 NUP37 79023 0 5 65
GSE54994 NUP37 79023 4 2 47
GSE60625 NUP37 79023 0 0 11
GSE74703 NUP37 79023 2 0 34
GSE74704 NUP37 79023 1 2 17
TCGA NUP37 79023 18 11 67

Total number of gains: 51; Total number of losses: 26; Total Number of normals: 411.  

 

Somatic mutations of NUP37:

 

Generating mutation plots.

 

Highly correlated genes for NUP37:

 

Showing top 20/1353 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUP37MRPL420.773068909
NUP37NDC10.74447811011
NUP37RAN0.73769712012
NUP37CENPN0.72969113013
NUP37CKS20.72928611011
NUP37RPA30.72650312012
NUP37RPAP30.71826911011
NUP37CDCA50.714429707
NUP37PRIM10.71341613011
NUP37DLGAP50.71299813012
NUP37CHEK10.71009913013
NUP37MRPL130.70917110010
NUP37CKS1B0.7073913012
NUP37CCNB20.70612312012
NUP37CDK10.70525512012
NUP37OIP50.70509311011
NUP37NUP930.70442312010
NUP37DCTPP10.7027612011
NUP37CSE1L0.7026211010
NUP37CCT20.70227511011

For details and further investigation, click here