| Full name: cytochrome c oxidase assembly factor COX18 | Alias Symbol: FLJ38991 | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 285521 | HGNC ID: HGNC:26801 | Ensembl Gene: ENSG00000163626 | OMIM ID: 610428 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COX18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX18 | 285521 | 227442_at | 0.5013 | 0.1168 | |
| GSE26886 | COX18 | 285521 | 227442_at | -0.0507 | 0.8821 | |
| GSE45670 | COX18 | 285521 | 227442_at | -0.0980 | 0.5130 | |
| GSE63941 | COX18 | 285521 | 227442_at | -0.4018 | 0.3954 | |
| GSE77861 | COX18 | 285521 | 227442_at | -0.3412 | 0.0758 | |
| SRP007169 | COX18 | 285521 | RNAseq | -0.7596 | 0.0608 | |
| SRP008496 | COX18 | 285521 | RNAseq | -0.4916 | 0.0508 | |
| SRP064894 | COX18 | 285521 | RNAseq | 0.2047 | 0.3188 | |
| SRP133303 | COX18 | 285521 | RNAseq | 0.2132 | 0.2379 | |
| SRP159526 | COX18 | 285521 | RNAseq | -0.1034 | 0.6557 | |
| SRP193095 | COX18 | 285521 | RNAseq | -0.2087 | 0.0165 | |
| SRP219564 | COX18 | 285521 | RNAseq | 0.0209 | 0.9447 | |
| TCGA | COX18 | 285521 | RNAseq | -0.1166 | 0.0868 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COX18 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of COX18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX18 | 285521 | 1 | 9 | 20 | |
| GSE20123 | COX18 | 285521 | 1 | 9 | 20 | |
| GSE43470 | COX18 | 285521 | 0 | 13 | 30 | |
| GSE46452 | COX18 | 285521 | 3 | 34 | 22 | |
| GSE47630 | COX18 | 285521 | 1 | 19 | 20 | |
| GSE54993 | COX18 | 285521 | 7 | 0 | 63 | |
| GSE54994 | COX18 | 285521 | 1 | 9 | 43 | |
| GSE60625 | COX18 | 285521 | 0 | 0 | 11 | |
| GSE74703 | COX18 | 285521 | 0 | 11 | 25 | |
| GSE74704 | COX18 | 285521 | 1 | 5 | 14 | |
| TCGA | COX18 | 285521 | 21 | 25 | 50 |
Total number of gains: 36; Total number of losses: 134; Total Number of normals: 318.
Somatic mutations of COX18:
Generating mutation plots.
Highly correlated genes for COX18:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX18 | ELMOD2 | 0.7466 | 4 | 0 | 4 |
| COX18 | HELQ | 0.722691 | 3 | 0 | 3 |
| COX18 | MOB1B | 0.716358 | 3 | 0 | 3 |
| COX18 | C4orf33 | 0.680459 | 3 | 0 | 3 |
| COX18 | CNOT6L | 0.666443 | 3 | 0 | 3 |
| COX18 | USP38 | 0.655611 | 4 | 0 | 4 |
| COX18 | ENOPH1 | 0.640795 | 4 | 0 | 4 |
| COX18 | COPS4 | 0.639612 | 3 | 0 | 3 |
| COX18 | ARFGEF2 | 0.626768 | 4 | 0 | 3 |
| COX18 | RCHY1 | 0.618659 | 4 | 0 | 4 |
| COX18 | GK5 | 0.610809 | 3 | 0 | 3 |
| COX18 | G3BP2 | 0.610405 | 4 | 0 | 3 |
| COX18 | SACM1L | 0.601746 | 3 | 0 | 3 |
| COX18 | SLC25A40 | 0.59842 | 3 | 0 | 3 |
| COX18 | CXorf38 | 0.592674 | 4 | 0 | 3 |
| COX18 | EXO5 | 0.589074 | 3 | 0 | 3 |
| COX18 | DCK | 0.587264 | 4 | 0 | 3 |
| COX18 | RALGAPB | 0.584614 | 4 | 0 | 3 |
| COX18 | UBE2D3 | 0.577039 | 3 | 0 | 3 |
| COX18 | HINT3 | 0.5679 | 4 | 0 | 3 |
For details and further investigation, click here
