| Full name: G3BP stress granule assembly factor 2 | Alias Symbol: KIAA0660 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 9908 | HGNC ID: HGNC:30291 | Ensembl Gene: ENSG00000138757 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of G3BP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | G3BP2 | 9908 | 208841_s_at | 0.3203 | 0.3862 | |
| GSE20347 | G3BP2 | 9908 | 208841_s_at | -0.1420 | 0.3186 | |
| GSE23400 | G3BP2 | 9908 | 208841_s_at | 0.2141 | 0.0340 | |
| GSE26886 | G3BP2 | 9908 | 208841_s_at | -0.1598 | 0.5272 | |
| GSE29001 | G3BP2 | 9908 | 208841_s_at | -0.2587 | 0.5262 | |
| GSE38129 | G3BP2 | 9908 | 208841_s_at | -0.0695 | 0.6193 | |
| GSE45670 | G3BP2 | 9908 | 208841_s_at | -0.1780 | 0.2446 | |
| GSE53622 | G3BP2 | 9908 | 157017 | -0.0819 | 0.3515 | |
| GSE53624 | G3BP2 | 9908 | 157017 | -0.2165 | 0.0115 | |
| GSE63941 | G3BP2 | 9908 | 208841_s_at | -0.3427 | 0.2648 | |
| GSE77861 | G3BP2 | 9908 | 208841_s_at | -0.1510 | 0.6161 | |
| GSE97050 | G3BP2 | 9908 | A_24_P380132 | -0.2457 | 0.2580 | |
| SRP007169 | G3BP2 | 9908 | RNAseq | -0.4884 | 0.2027 | |
| SRP008496 | G3BP2 | 9908 | RNAseq | -0.3036 | 0.1681 | |
| SRP064894 | G3BP2 | 9908 | RNAseq | -0.3804 | 0.0484 | |
| SRP133303 | G3BP2 | 9908 | RNAseq | 0.5810 | 0.0252 | |
| SRP159526 | G3BP2 | 9908 | RNAseq | -0.2372 | 0.2664 | |
| SRP193095 | G3BP2 | 9908 | RNAseq | -0.3552 | 0.0002 | |
| SRP219564 | G3BP2 | 9908 | RNAseq | -0.3578 | 0.3286 | |
| TCGA | G3BP2 | 9908 | RNAseq | -0.1285 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by G3BP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of G3BP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | G3BP2 | 9908 | 2 | 9 | 19 | |
| GSE20123 | G3BP2 | 9908 | 2 | 9 | 19 | |
| GSE43470 | G3BP2 | 9908 | 0 | 13 | 30 | |
| GSE46452 | G3BP2 | 9908 | 2 | 35 | 22 | |
| GSE47630 | G3BP2 | 9908 | 1 | 19 | 20 | |
| GSE54993 | G3BP2 | 9908 | 7 | 0 | 63 | |
| GSE54994 | G3BP2 | 9908 | 1 | 9 | 43 | |
| GSE60625 | G3BP2 | 9908 | 0 | 0 | 11 | |
| GSE74703 | G3BP2 | 9908 | 0 | 11 | 25 | |
| GSE74704 | G3BP2 | 9908 | 2 | 5 | 13 | |
| TCGA | G3BP2 | 9908 | 17 | 30 | 49 |
Total number of gains: 34; Total number of losses: 140; Total Number of normals: 314.
Somatic mutations of G3BP2:
Generating mutation plots.
Highly correlated genes for G3BP2:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| G3BP2 | RRM2B | 0.764635 | 3 | 0 | 3 |
| G3BP2 | VPS29 | 0.751439 | 3 | 0 | 3 |
| G3BP2 | AP3M2 | 0.730734 | 3 | 0 | 3 |
| G3BP2 | C1orf174 | 0.711739 | 3 | 0 | 3 |
| G3BP2 | INTS10 | 0.709873 | 3 | 0 | 3 |
| G3BP2 | C12orf29 | 0.701916 | 4 | 0 | 3 |
| G3BP2 | OSCAR | 0.694162 | 3 | 0 | 3 |
| G3BP2 | RAB9A | 0.688546 | 4 | 0 | 3 |
| G3BP2 | RBM8A | 0.688529 | 4 | 0 | 3 |
| G3BP2 | ZNF627 | 0.684843 | 4 | 0 | 4 |
| G3BP2 | ATG12 | 0.679822 | 4 | 0 | 3 |
| G3BP2 | NUP54 | 0.674855 | 13 | 0 | 12 |
| G3BP2 | ATF1 | 0.674466 | 6 | 0 | 4 |
| G3BP2 | SUB1 | 0.674327 | 4 | 0 | 3 |
| G3BP2 | PEX2 | 0.671547 | 6 | 0 | 5 |
| G3BP2 | PSIP1 | 0.671514 | 3 | 0 | 3 |
| G3BP2 | TXNDC9 | 0.670375 | 4 | 0 | 4 |
| G3BP2 | NDUFB5 | 0.670371 | 3 | 0 | 3 |
| G3BP2 | SRFBP1 | 0.6675 | 3 | 0 | 3 |
| G3BP2 | SEC22A | 0.658332 | 4 | 0 | 4 |
For details and further investigation, click here
