| Full name: deoxycytidine kinase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 1633 | HGNC ID: HGNC:2704 | Ensembl Gene: ENSG00000156136 | OMIM ID: 125450 |
| Drug and gene relationship at DGIdb | |||
Expression of DCK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCK | 1633 | 203302_at | 0.5429 | 0.2594 | |
| GSE20347 | DCK | 1633 | 203302_at | 0.4383 | 0.0125 | |
| GSE23400 | DCK | 1633 | 203302_at | 0.5697 | 0.0000 | |
| GSE26886 | DCK | 1633 | 203302_at | 0.2189 | 0.4820 | |
| GSE29001 | DCK | 1633 | 203302_at | 0.7692 | 0.1426 | |
| GSE38129 | DCK | 1633 | 203302_at | 0.5475 | 0.0015 | |
| GSE45670 | DCK | 1633 | 203302_at | 0.1518 | 0.4518 | |
| GSE53622 | DCK | 1633 | 54654 | 0.2695 | 0.0211 | |
| GSE53624 | DCK | 1633 | 54654 | 0.3475 | 0.0064 | |
| GSE63941 | DCK | 1633 | 203302_at | 0.2331 | 0.6637 | |
| GSE77861 | DCK | 1633 | 203302_at | 0.0338 | 0.9522 | |
| GSE97050 | DCK | 1633 | A_24_P89080 | 0.3201 | 0.3427 | |
| SRP007169 | DCK | 1633 | RNAseq | 0.4557 | 0.2680 | |
| SRP008496 | DCK | 1633 | RNAseq | 0.6114 | 0.0079 | |
| SRP064894 | DCK | 1633 | RNAseq | 0.3103 | 0.2439 | |
| SRP133303 | DCK | 1633 | RNAseq | 0.6512 | 0.0004 | |
| SRP159526 | DCK | 1633 | RNAseq | -0.1131 | 0.7132 | |
| SRP193095 | DCK | 1633 | RNAseq | 0.0580 | 0.6662 | |
| SRP219564 | DCK | 1633 | RNAseq | 0.1508 | 0.7188 | |
| TCGA | DCK | 1633 | RNAseq | 0.1819 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCK | 1633 | 0 | 11 | 19 | |
| GSE20123 | DCK | 1633 | 0 | 11 | 19 | |
| GSE43470 | DCK | 1633 | 0 | 13 | 30 | |
| GSE46452 | DCK | 1633 | 2 | 35 | 22 | |
| GSE47630 | DCK | 1633 | 1 | 19 | 20 | |
| GSE54993 | DCK | 1633 | 7 | 0 | 63 | |
| GSE54994 | DCK | 1633 | 1 | 9 | 43 | |
| GSE60625 | DCK | 1633 | 0 | 0 | 11 | |
| GSE74703 | DCK | 1633 | 0 | 11 | 25 | |
| GSE74704 | DCK | 1633 | 0 | 6 | 14 | |
| TCGA | DCK | 1633 | 16 | 28 | 52 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of DCK:
Generating mutation plots.
Highly correlated genes for DCK:
Showing top 20/790 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCK | ZKSCAN4 | 0.717383 | 3 | 0 | 3 |
| DCK | UTP23 | 0.716956 | 3 | 0 | 3 |
| DCK | TRUB1 | 0.704163 | 5 | 0 | 5 |
| DCK | EMB | 0.703653 | 3 | 0 | 3 |
| DCK | SNX30 | 0.702978 | 4 | 0 | 3 |
| DCK | MBIP | 0.693991 | 3 | 0 | 3 |
| DCK | ITPRIPL2 | 0.691173 | 3 | 0 | 3 |
| DCK | LRRK1 | 0.686468 | 3 | 0 | 3 |
| DCK | RPP38 | 0.685607 | 3 | 0 | 3 |
| DCK | USP37 | 0.683188 | 3 | 0 | 3 |
| DCK | NAGPA | 0.681706 | 3 | 0 | 3 |
| DCK | LRP6 | 0.680731 | 3 | 0 | 3 |
| DCK | RRM2B | 0.678389 | 3 | 0 | 3 |
| DCK | CRLS1 | 0.674483 | 4 | 0 | 3 |
| DCK | RALGAPB | 0.672535 | 3 | 0 | 3 |
| DCK | RCN2 | 0.672396 | 9 | 0 | 8 |
| DCK | RBM12 | 0.671826 | 8 | 0 | 8 |
| DCK | PHF14 | 0.671351 | 3 | 0 | 3 |
| DCK | PIK3CB | 0.670962 | 3 | 0 | 3 |
| DCK | ZNF174 | 0.669107 | 3 | 0 | 3 |
For details and further investigation, click here
