| Full name: arginyltransferase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 11101 | HGNC ID: HGNC:782 | Ensembl Gene: ENSG00000107669 | OMIM ID: 607103 |
| Drug and gene relationship at DGIdb | |||
Expression of ATE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATE1 | 11101 | 225497_at | -0.2304 | 0.6758 | |
| GSE26886 | ATE1 | 11101 | 225497_at | -0.2246 | 0.4429 | |
| GSE45670 | ATE1 | 11101 | 225497_at | -0.3168 | 0.0253 | |
| GSE53622 | ATE1 | 11101 | 27299 | -0.3429 | 0.0000 | |
| GSE53624 | ATE1 | 11101 | 27299 | -0.5145 | 0.0000 | |
| GSE63941 | ATE1 | 11101 | 225497_at | -0.5238 | 0.2127 | |
| GSE77861 | ATE1 | 11101 | 234584_s_at | 0.0006 | 0.9976 | |
| GSE97050 | ATE1 | 11101 | A_23_P138574 | -0.5308 | 0.3566 | |
| SRP007169 | ATE1 | 11101 | RNAseq | -0.4321 | 0.3861 | |
| SRP008496 | ATE1 | 11101 | RNAseq | -0.4185 | 0.1318 | |
| SRP064894 | ATE1 | 11101 | RNAseq | -0.4674 | 0.0199 | |
| SRP133303 | ATE1 | 11101 | RNAseq | -0.0652 | 0.5188 | |
| SRP159526 | ATE1 | 11101 | RNAseq | -0.2418 | 0.6072 | |
| SRP193095 | ATE1 | 11101 | RNAseq | -0.2544 | 0.0018 | |
| SRP219564 | ATE1 | 11101 | RNAseq | -0.5107 | 0.0602 | |
| TCGA | ATE1 | 11101 | RNAseq | -0.1418 | 0.0239 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATE1 | 11101 | 2 | 7 | 21 | |
| GSE20123 | ATE1 | 11101 | 2 | 7 | 21 | |
| GSE43470 | ATE1 | 11101 | 0 | 9 | 34 | |
| GSE46452 | ATE1 | 11101 | 0 | 11 | 48 | |
| GSE47630 | ATE1 | 11101 | 2 | 14 | 24 | |
| GSE54993 | ATE1 | 11101 | 8 | 1 | 61 | |
| GSE54994 | ATE1 | 11101 | 1 | 9 | 43 | |
| GSE60625 | ATE1 | 11101 | 0 | 0 | 11 | |
| GSE74703 | ATE1 | 11101 | 0 | 6 | 30 | |
| GSE74704 | ATE1 | 11101 | 1 | 2 | 17 | |
| TCGA | ATE1 | 11101 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 94; Total Number of normals: 374.
Somatic mutations of ATE1:
Generating mutation plots.
Highly correlated genes for ATE1:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATE1 | UNC50 | 0.693021 | 4 | 0 | 3 |
| ATE1 | APC | 0.655481 | 3 | 0 | 3 |
| ATE1 | VPS26A | 0.640423 | 4 | 0 | 3 |
| ATE1 | RRN3 | 0.636578 | 3 | 0 | 3 |
| ATE1 | COX7A2 | 0.635028 | 4 | 0 | 3 |
| ATE1 | THAP1 | 0.613571 | 3 | 0 | 3 |
| ATE1 | TRIM4 | 0.607151 | 4 | 0 | 3 |
| ATE1 | NIPSNAP3A | 0.605656 | 3 | 0 | 3 |
| ATE1 | IMPACT | 0.599035 | 4 | 0 | 3 |
| ATE1 | TACC2 | 0.592903 | 4 | 0 | 3 |
| ATE1 | ATAD1 | 0.592251 | 4 | 0 | 3 |
| ATE1 | ANKRD28 | 0.590227 | 3 | 0 | 3 |
| ATE1 | SLC35A3 | 0.574513 | 3 | 0 | 3 |
| ATE1 | EIF3A | 0.573153 | 5 | 0 | 4 |
| ATE1 | SORBS1 | 0.57254 | 3 | 0 | 3 |
| ATE1 | NSMCE4A | 0.569606 | 4 | 0 | 3 |
| ATE1 | ZNF518A | 0.5691 | 4 | 0 | 3 |
| ATE1 | PGAM1 | 0.564507 | 3 | 0 | 3 |
| ATE1 | CD46 | 0.563318 | 4 | 0 | 3 |
| ATE1 | PCP4 | 0.556853 | 4 | 0 | 3 |
For details and further investigation, click here
