| Full name: ATPase Na+/K+ transporting subunit beta 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 481 | HGNC ID: HGNC:804 | Ensembl Gene: ENSG00000143153 | OMIM ID: 182330 |
| Drug and gene relationship at DGIdb | |||
ATP1B1 involved pathways:
Expression of ATP1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP1B1 | 481 | 201242_s_at | -1.1744 | 0.0475 | |
| GSE20347 | ATP1B1 | 481 | 201242_s_at | -0.3746 | 0.0793 | |
| GSE23400 | ATP1B1 | 481 | 201243_s_at | -0.6385 | 0.0000 | |
| GSE26886 | ATP1B1 | 481 | 201243_s_at | -1.3543 | 0.0000 | |
| GSE29001 | ATP1B1 | 481 | 201243_s_at | -0.4506 | 0.2364 | |
| GSE38129 | ATP1B1 | 481 | 201242_s_at | -0.3143 | 0.4200 | |
| GSE45670 | ATP1B1 | 481 | 201243_s_at | -0.4923 | 0.0252 | |
| GSE63941 | ATP1B1 | 481 | 201242_s_at | 2.6356 | 0.0166 | |
| GSE77861 | ATP1B1 | 481 | 201242_s_at | -0.2089 | 0.2076 | |
| GSE97050 | ATP1B1 | 481 | A_23_P62932 | -1.1244 | 0.0454 | |
| SRP007169 | ATP1B1 | 481 | RNAseq | -2.4902 | 0.0000 | |
| SRP008496 | ATP1B1 | 481 | RNAseq | -1.6473 | 0.0000 | |
| SRP064894 | ATP1B1 | 481 | RNAseq | -1.2063 | 0.0000 | |
| SRP133303 | ATP1B1 | 481 | RNAseq | -0.4242 | 0.0768 | |
| SRP159526 | ATP1B1 | 481 | RNAseq | 0.1156 | 0.8363 | |
| SRP193095 | ATP1B1 | 481 | RNAseq | -0.8435 | 0.0000 | |
| SRP219564 | ATP1B1 | 481 | RNAseq | -0.7257 | 0.2678 | |
| TCGA | ATP1B1 | 481 | RNAseq | -0.3919 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by ATP1B1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ATP1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP1B1 | 481 | 11 | 1 | 18 | |
| GSE20123 | ATP1B1 | 481 | 11 | 1 | 18 | |
| GSE43470 | ATP1B1 | 481 | 7 | 2 | 34 | |
| GSE46452 | ATP1B1 | 481 | 3 | 1 | 55 | |
| GSE47630 | ATP1B1 | 481 | 14 | 0 | 26 | |
| GSE54993 | ATP1B1 | 481 | 0 | 6 | 64 | |
| GSE54994 | ATP1B1 | 481 | 16 | 0 | 37 | |
| GSE60625 | ATP1B1 | 481 | 0 | 0 | 11 | |
| GSE74703 | ATP1B1 | 481 | 7 | 2 | 27 | |
| GSE74704 | ATP1B1 | 481 | 5 | 0 | 15 | |
| TCGA | ATP1B1 | 481 | 44 | 3 | 49 |
Total number of gains: 118; Total number of losses: 16; Total Number of normals: 354.
Somatic mutations of ATP1B1:
Generating mutation plots.
Highly correlated genes for ATP1B1:
Showing top 20/564 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP1B1 | TCP11L2 | 0.745118 | 3 | 0 | 3 |
| ATP1B1 | BOK | 0.738189 | 3 | 0 | 3 |
| ATP1B1 | RAB10 | 0.737938 | 4 | 0 | 3 |
| ATP1B1 | MUC15 | 0.736901 | 4 | 0 | 4 |
| ATP1B1 | BNIPL | 0.692863 | 5 | 0 | 5 |
| ATP1B1 | SH3PXD2A-AS1 | 0.686802 | 3 | 0 | 3 |
| ATP1B1 | LYNX1 | 0.682975 | 4 | 0 | 3 |
| ATP1B1 | GJB2 | 0.677653 | 4 | 0 | 4 |
| ATP1B1 | MPZL2 | 0.67568 | 6 | 0 | 6 |
| ATP1B1 | RAD23B | 0.675231 | 3 | 0 | 3 |
| ATP1B1 | MCEE | 0.671155 | 4 | 0 | 3 |
| ATP1B1 | SH3BGRL2 | 0.666368 | 5 | 0 | 4 |
| ATP1B1 | KRT78 | 0.666326 | 5 | 0 | 4 |
| ATP1B1 | KCNK6 | 0.665306 | 3 | 0 | 3 |
| ATP1B1 | TVP23B | 0.665226 | 4 | 0 | 4 |
| ATP1B1 | ATP13A4 | 0.663934 | 5 | 0 | 4 |
| ATP1B1 | A2ML1 | 0.658663 | 5 | 0 | 3 |
| ATP1B1 | TMEM154 | 0.655746 | 3 | 0 | 3 |
| ATP1B1 | VSIG10L | 0.655116 | 5 | 0 | 4 |
| ATP1B1 | FCHO2 | 0.652614 | 5 | 0 | 5 |
For details and further investigation, click here
