| Full name: oxidation resistance 1 | Alias Symbol: TLDC3 | ||
| Type: protein-coding gene | Cytoband: 8q23.1 | ||
| Entrez ID: 55074 | HGNC ID: HGNC:15822 | Ensembl Gene: ENSG00000164830 | OMIM ID: 605609 |
| Drug and gene relationship at DGIdb | |||
Expression of OXR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OXR1 | 55074 | 222553_x_at | -0.5508 | 0.0845 | |
| GSE20347 | OXR1 | 55074 | 218197_s_at | -0.7157 | 0.0004 | |
| GSE23400 | OXR1 | 55074 | 218197_s_at | -0.2582 | 0.0004 | |
| GSE26886 | OXR1 | 55074 | 222553_x_at | -0.8175 | 0.0108 | |
| GSE29001 | OXR1 | 55074 | 218197_s_at | -0.7049 | 0.0331 | |
| GSE38129 | OXR1 | 55074 | 218197_s_at | -0.7146 | 0.0000 | |
| GSE45670 | OXR1 | 55074 | 218197_s_at | -0.8773 | 0.0000 | |
| GSE53622 | OXR1 | 55074 | 22662 | -0.5772 | 0.0000 | |
| GSE53624 | OXR1 | 55074 | 78875 | -0.8693 | 0.0000 | |
| GSE63941 | OXR1 | 55074 | 222553_x_at | 0.0649 | 0.9414 | |
| GSE77861 | OXR1 | 55074 | 222553_x_at | -1.0059 | 0.0006 | |
| GSE97050 | OXR1 | A_19_P00322418 | -0.8068 | 0.1269 | ||
| SRP007169 | OXR1 | 55074 | RNAseq | -1.8492 | 0.0000 | |
| SRP008496 | OXR1 | 55074 | RNAseq | -1.5528 | 0.0000 | |
| SRP064894 | OXR1 | 55074 | RNAseq | -0.5381 | 0.0279 | |
| SRP133303 | OXR1 | 55074 | RNAseq | -0.8097 | 0.0000 | |
| SRP159526 | OXR1 | 55074 | RNAseq | -0.8433 | 0.0000 | |
| SRP193095 | OXR1 | 55074 | RNAseq | -1.0831 | 0.0000 | |
| SRP219564 | OXR1 | 55074 | RNAseq | -0.7898 | 0.0125 | |
| TCGA | OXR1 | 55074 | RNAseq | -0.1745 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by OXR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OXR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OXR1 | 55074 | 16 | 0 | 14 | |
| GSE20123 | OXR1 | 55074 | 17 | 0 | 13 | |
| GSE43470 | OXR1 | 55074 | 22 | 0 | 21 | |
| GSE46452 | OXR1 | 55074 | 25 | 0 | 34 | |
| GSE47630 | OXR1 | 55074 | 24 | 0 | 16 | |
| GSE54993 | OXR1 | 55074 | 0 | 20 | 50 | |
| GSE54994 | OXR1 | 55074 | 37 | 1 | 15 | |
| GSE60625 | OXR1 | 55074 | 0 | 4 | 7 | |
| GSE74703 | OXR1 | 55074 | 19 | 0 | 17 | |
| GSE74704 | OXR1 | 55074 | 11 | 0 | 9 | |
| TCGA | OXR1 | 55074 | 60 | 1 | 35 |
Total number of gains: 231; Total number of losses: 26; Total Number of normals: 231.
Somatic mutations of OXR1:
Generating mutation plots.
Highly correlated genes for OXR1:
Showing top 20/1489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OXR1 | NFIX | 0.750494 | 6 | 0 | 6 |
| OXR1 | KDM5D | 0.737992 | 3 | 0 | 3 |
| OXR1 | CIPC | 0.727377 | 6 | 0 | 6 |
| OXR1 | FBXL3 | 0.725554 | 6 | 0 | 5 |
| OXR1 | ARHGAP31 | 0.722213 | 3 | 0 | 3 |
| OXR1 | LRRK2 | 0.718837 | 7 | 0 | 7 |
| OXR1 | CLYBL | 0.710965 | 6 | 0 | 6 |
| OXR1 | GOLGA4 | 0.709153 | 8 | 0 | 8 |
| OXR1 | FXYD1 | 0.708537 | 3 | 0 | 3 |
| OXR1 | FBXO8 | 0.706283 | 7 | 0 | 7 |
| OXR1 | CGNL1 | 0.705615 | 7 | 0 | 7 |
| OXR1 | LMBRD1 | 0.705365 | 11 | 0 | 10 |
| OXR1 | KCTD10 | 0.704825 | 3 | 0 | 3 |
| OXR1 | ANGPTL1 | 0.704689 | 5 | 0 | 5 |
| OXR1 | LINC00938 | 0.704431 | 4 | 0 | 4 |
| OXR1 | NFIA | 0.703293 | 7 | 0 | 6 |
| OXR1 | SH3BGRL2 | 0.702411 | 7 | 0 | 6 |
| OXR1 | CTTNBP2 | 0.702157 | 6 | 0 | 6 |
| OXR1 | HDHD2 | 0.700931 | 5 | 0 | 5 |
| OXR1 | RAB9B | 0.699037 | 5 | 0 | 5 |
For details and further investigation, click here
