| Full name: solute carrier family 6 member 16 | Alias Symbol: NTT5 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 28968 | HGNC ID: HGNC:13622 | Ensembl Gene: ENSG00000063127 | OMIM ID: 607972 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A16 | 28968 | 1569940_at | -0.2491 | 0.7695 | |
| GSE20347 | SLC6A16 | 28968 | 219820_at | 0.0787 | 0.4430 | |
| GSE23400 | SLC6A16 | 28968 | 219820_at | -0.0539 | 0.3029 | |
| GSE26886 | SLC6A16 | 28968 | 1569940_at | 0.2483 | 0.1094 | |
| GSE29001 | SLC6A16 | 28968 | 219820_at | -0.1832 | 0.1770 | |
| GSE38129 | SLC6A16 | 28968 | 219820_at | -0.2170 | 0.0738 | |
| GSE45670 | SLC6A16 | 28968 | 1569940_at | -0.4165 | 0.0813 | |
| GSE53622 | SLC6A16 | 28968 | 27313 | -1.5008 | 0.0000 | |
| GSE53624 | SLC6A16 | 28968 | 27313 | -1.2981 | 0.0000 | |
| GSE63941 | SLC6A16 | 28968 | 1569940_at | -0.3091 | 0.5082 | |
| GSE77861 | SLC6A16 | 28968 | 1569940_at | 0.1197 | 0.2955 | |
| SRP064894 | SLC6A16 | 28968 | RNAseq | -0.6929 | 0.0162 | |
| SRP133303 | SLC6A16 | 28968 | RNAseq | -0.7636 | 0.0002 | |
| SRP159526 | SLC6A16 | 28968 | RNAseq | -0.2972 | 0.3923 | |
| SRP219564 | SLC6A16 | 28968 | RNAseq | -1.2727 | 0.0174 | |
| TCGA | SLC6A16 | 28968 | RNAseq | -1.0937 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SLC6A16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A16 | 28968 | 4 | 4 | 22 | |
| GSE20123 | SLC6A16 | 28968 | 4 | 3 | 23 | |
| GSE43470 | SLC6A16 | 28968 | 4 | 11 | 28 | |
| GSE46452 | SLC6A16 | 28968 | 45 | 1 | 13 | |
| GSE47630 | SLC6A16 | 28968 | 10 | 6 | 24 | |
| GSE54993 | SLC6A16 | 28968 | 17 | 4 | 49 | |
| GSE54994 | SLC6A16 | 28968 | 4 | 14 | 35 | |
| GSE60625 | SLC6A16 | 28968 | 9 | 0 | 2 | |
| GSE74703 | SLC6A16 | 28968 | 4 | 7 | 25 | |
| GSE74704 | SLC6A16 | 28968 | 4 | 1 | 15 | |
| TCGA | SLC6A16 | 28968 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of SLC6A16:
Generating mutation plots.
Highly correlated genes for SLC6A16:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A16 | VGLL3 | 0.638511 | 3 | 0 | 3 |
| SLC6A16 | CNR1 | 0.632655 | 3 | 0 | 3 |
| SLC6A16 | FAM107A | 0.629713 | 5 | 0 | 4 |
| SLC6A16 | CBX7 | 0.629171 | 5 | 0 | 5 |
| SLC6A16 | PYGM | 0.607929 | 4 | 0 | 4 |
| SLC6A16 | RIC3 | 0.606845 | 3 | 0 | 3 |
| SLC6A16 | MYRIP | 0.600759 | 5 | 0 | 4 |
| SLC6A16 | HSPB6 | 0.600312 | 5 | 0 | 4 |
| SLC6A16 | MYH11 | 0.59786 | 5 | 0 | 4 |
| SLC6A16 | NR3C2 | 0.59633 | 4 | 0 | 3 |
| SLC6A16 | OR1A1 | 0.596069 | 3 | 0 | 3 |
| SLC6A16 | CFP | 0.589548 | 4 | 0 | 3 |
| SLC6A16 | CPO | 0.588902 | 3 | 0 | 3 |
| SLC6A16 | CACNB4 | 0.585791 | 5 | 0 | 4 |
| SLC6A16 | ITGA7 | 0.585263 | 5 | 0 | 5 |
| SLC6A16 | RERGL | 0.581963 | 4 | 0 | 3 |
| SLC6A16 | ASPA | 0.581741 | 5 | 0 | 4 |
| SLC6A16 | TGFBR3 | 0.580635 | 5 | 0 | 4 |
| SLC6A16 | LGI1 | 0.580005 | 5 | 0 | 4 |
| SLC6A16 | MFAP4 | 0.575009 | 5 | 0 | 5 |
For details and further investigation, click here
