CRELD2

 

Full name: cysteine rich with EGF like domains 2 Alias Symbol: MGC11256
Type: protein-coding gene Cytoband: 22q13.33
Entrez ID: 79174 HGNC ID: HGNC:28150 Ensembl Gene: ENSG00000184164 OMIM ID: 607171
Drug and gene relationship at DGIdb

 

Expression of CRELD2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CRELD2 79174 218358_at 0.7042 0.1863
GSE20347 CRELD2 79174 218358_at 0.1213 0.4620
GSE23400 CRELD2 79174 218358_at 0.2303 0.0000
GSE26886 CRELD2 79174 218358_at 0.0285 0.9332
GSE29001 CRELD2 79174 218358_at 0.2563 0.1979
GSE38129 CRELD2 79174 218358_at 0.2474 0.0546
GSE45670 CRELD2 79174 218358_at 0.5656 0.0022
GSE53622 CRELD2 79174 134157 0.1351 0.0112
GSE53624 CRELD2 79174 134157 0.1707 0.0000
GSE63941 CRELD2 79174 218358_at -0.8922 0.1895
GSE77861 CRELD2 79174 218358_at 0.2975 0.0665
GSE97050 CRELD2 79174 A_23_P33465 0.2941 0.1860
SRP007169 CRELD2 79174 RNAseq 0.0346 0.9387
SRP008496 CRELD2 79174 RNAseq -0.0947 0.7010
SRP064894 CRELD2 79174 RNAseq 1.0120 0.0003
SRP133303 CRELD2 79174 RNAseq 0.7609 0.0009
SRP159526 CRELD2 79174 RNAseq 0.8080 0.0008
SRP193095 CRELD2 79174 RNAseq 0.2860 0.0734
SRP219564 CRELD2 79174 RNAseq 1.1528 0.0243
TCGA CRELD2 79174 RNAseq -0.0994 0.1217

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by CRELD2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CRELD2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CRELD2 79174 3 8 19
GSE20123 CRELD2 79174 3 8 19
GSE43470 CRELD2 79174 2 8 33
GSE46452 CRELD2 79174 31 2 26
GSE47630 CRELD2 79174 9 4 27
GSE54993 CRELD2 79174 4 6 60
GSE54994 CRELD2 79174 11 8 34
GSE60625 CRELD2 79174 5 0 6
GSE74703 CRELD2 79174 2 6 28
GSE74704 CRELD2 79174 1 4 15
TCGA CRELD2 79174 26 16 54

Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.  

 

Somatic mutations of CRELD2:

 

Generating mutation plots.

 

Highly correlated genes for CRELD2:

 

Showing top 20/598 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CRELD2B3GALT60.738439404
CRELD2NONO0.735634404
CRELD2APOE0.733586303
CRELD2DGKD0.724153303
CRELD2GRAMD1A0.722404303
CRELD2REC80.708452303
CRELD2TAF20.700962404
CRELD2WDYHV10.700962404
CRELD2AGO20.695924303
CRELD2MSTO10.69062403
CRELD2CHST10.689086404
CRELD2ZNF70.686707404
CRELD2STMN10.686413404
CRELD2CEP2500.685697303
CRELD2RECQL40.677338303
CRELD2FUCA20.67616404
CRELD2PPP6R20.674874303
CRELD2CDC370.674721303
CRELD2UBA20.674456303
CRELD2RAB150.673177403

For details and further investigation, click here