| Full name: carbohydrate sulfotransferase 1 | Alias Symbol: C6ST|KSGal6ST | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 8534 | HGNC ID: HGNC:1969 | Ensembl Gene: ENSG00000175264 | OMIM ID: 603797 |
| Drug and gene relationship at DGIdb | |||
Expression of CHST1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHST1 | 8534 | 205567_at | 1.5990 | 0.0523 | |
| GSE20347 | CHST1 | 8534 | 205567_at | 1.0659 | 0.0004 | |
| GSE23400 | CHST1 | 8534 | 205567_at | 0.5234 | 0.0000 | |
| GSE26886 | CHST1 | 8534 | 205567_at | 0.3140 | 0.0370 | |
| GSE29001 | CHST1 | 8534 | 205567_at | 0.6295 | 0.0268 | |
| GSE38129 | CHST1 | 8534 | 205567_at | 1.3245 | 0.0000 | |
| GSE45670 | CHST1 | 8534 | 205567_at | 1.0664 | 0.0188 | |
| GSE53622 | CHST1 | 8534 | 47726 | 2.1230 | 0.0000 | |
| GSE53624 | CHST1 | 8534 | 47726 | 2.4337 | 0.0000 | |
| GSE63941 | CHST1 | 8534 | 205567_at | 0.1403 | 0.7701 | |
| GSE77861 | CHST1 | 8534 | 205567_at | 0.9430 | 0.0343 | |
| GSE97050 | CHST1 | 8534 | A_23_P98205 | 1.1171 | 0.1161 | |
| SRP007169 | CHST1 | 8534 | RNAseq | 2.9357 | 0.0031 | |
| SRP064894 | CHST1 | 8534 | RNAseq | 3.0543 | 0.0000 | |
| SRP133303 | CHST1 | 8534 | RNAseq | 1.4285 | 0.0000 | |
| SRP159526 | CHST1 | 8534 | RNAseq | 3.4745 | 0.0001 | |
| SRP193095 | CHST1 | 8534 | RNAseq | 2.3678 | 0.0000 | |
| SRP219564 | CHST1 | 8534 | RNAseq | 2.0404 | 0.0125 | |
| TCGA | CHST1 | 8534 | RNAseq | 1.2694 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by CHST1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHST1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHST1 | 8534 | 2 | 7 | 21 | |
| GSE20123 | CHST1 | 8534 | 1 | 7 | 22 | |
| GSE43470 | CHST1 | 8534 | 2 | 4 | 37 | |
| GSE46452 | CHST1 | 8534 | 8 | 5 | 46 | |
| GSE47630 | CHST1 | 8534 | 3 | 9 | 28 | |
| GSE54993 | CHST1 | 8534 | 3 | 0 | 67 | |
| GSE54994 | CHST1 | 8534 | 4 | 9 | 40 | |
| GSE60625 | CHST1 | 8534 | 0 | 0 | 11 | |
| GSE74703 | CHST1 | 8534 | 2 | 2 | 32 | |
| GSE74704 | CHST1 | 8534 | 1 | 5 | 14 | |
| TCGA | CHST1 | 8534 | 16 | 18 | 62 |
Total number of gains: 42; Total number of losses: 66; Total Number of normals: 380.
Somatic mutations of CHST1:
Generating mutation plots.
Highly correlated genes for CHST1:
Showing top 20/1342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHST1 | CAPN12 | 0.858653 | 3 | 0 | 3 |
| CHST1 | PALM2 | 0.764801 | 3 | 0 | 3 |
| CHST1 | SYCP2 | 0.750403 | 3 | 0 | 3 |
| CHST1 | SNAP47 | 0.740291 | 3 | 0 | 3 |
| CHST1 | GPRIN1 | 0.7311 | 4 | 0 | 4 |
| CHST1 | DCAF13 | 0.727415 | 5 | 0 | 5 |
| CHST1 | NLN | 0.726758 | 4 | 0 | 4 |
| CHST1 | FAM89A | 0.724904 | 3 | 0 | 3 |
| CHST1 | PYCR2 | 0.715707 | 3 | 0 | 3 |
| CHST1 | BRAT1 | 0.698335 | 6 | 0 | 6 |
| CHST1 | ZNF707 | 0.694344 | 3 | 0 | 3 |
| CHST1 | CAGE1 | 0.692702 | 5 | 0 | 5 |
| CHST1 | UBQLN4 | 0.691474 | 3 | 0 | 3 |
| CHST1 | CRELD2 | 0.689086 | 4 | 0 | 4 |
| CHST1 | DKC1 | 0.686062 | 3 | 0 | 3 |
| CHST1 | MAD2L2 | 0.684776 | 3 | 0 | 3 |
| CHST1 | PDIA5 | 0.683011 | 3 | 0 | 3 |
| CHST1 | GORAB | 0.68284 | 6 | 0 | 6 |
| CHST1 | UBE2T | 0.681379 | 6 | 0 | 6 |
| CHST1 | IL4I1 | 0.680614 | 4 | 0 | 4 |
For details and further investigation, click here
