| Full name: PPP5 tetratricopeptide repeat domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 100506012 | HGNC ID: HGNC:44209 | Ensembl Gene: ENSG00000230510 | OMIM ID: |
PPP5D1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway |
Expression of PPP5D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP5D1 | 100506012 | 242253_at | 0.0930 | 0.8709 | |
| GSE26886 | PPP5D1 | 100506012 | 242253_at | 0.1669 | 0.2468 | |
| GSE45670 | PPP5D1 | 100506012 | 242253_at | -0.2640 | 0.0223 | |
| GSE63941 | PPP5D1 | 100506012 | 242253_at | -0.9154 | 0.0100 | |
| GSE77861 | PPP5D1 | 100506012 | 242253_at | 0.0151 | 0.8771 | |
| SRP133303 | PPP5D1 | 100506012 | RNAseq | -0.0019 | 0.9883 | |
| SRP159526 | PPP5D1 | 100506012 | RNAseq | -0.2221 | 0.6605 | |
| SRP193095 | PPP5D1 | 100506012 | RNAseq | 0.2766 | 0.0774 | |
| SRP219564 | PPP5D1 | 100506012 | RNAseq | -0.2316 | 0.6008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of PPP5D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP5D1 | 100506012 | 4 | 5 | 21 | |
| GSE20123 | PPP5D1 | 100506012 | 4 | 4 | 22 | |
| GSE43470 | PPP5D1 | 100506012 | 3 | 11 | 29 | |
| GSE46452 | PPP5D1 | 100506012 | 45 | 1 | 13 | |
| GSE47630 | PPP5D1 | 100506012 | 8 | 7 | 25 | |
| GSE54993 | PPP5D1 | 100506012 | 17 | 4 | 49 | |
| GSE54994 | PPP5D1 | 100506012 | 5 | 13 | 35 | |
| GSE60625 | PPP5D1 | 100506012 | 9 | 0 | 2 | |
| GSE74703 | PPP5D1 | 100506012 | 3 | 7 | 26 | |
| GSE74704 | PPP5D1 | 100506012 | 4 | 2 | 14 | |
| TCGA | PPP5D1 | 100506012 | 15 | 15 | 66 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of PPP5D1:
Generating mutation plots.
Highly correlated genes for PPP5D1:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP5D1 | SNED1 | 0.700096 | 3 | 0 | 3 |
| PPP5D1 | CSN3 | 0.669675 | 3 | 0 | 3 |
| PPP5D1 | PIGQ | 0.664595 | 3 | 0 | 3 |
| PPP5D1 | LMO3 | 0.646614 | 3 | 0 | 3 |
| PPP5D1 | DPP6 | 0.631565 | 3 | 0 | 3 |
| PPP5D1 | TSC22D1-AS1 | 0.627608 | 4 | 0 | 4 |
| PPP5D1 | SFRP4 | 0.626549 | 3 | 0 | 3 |
| PPP5D1 | C3orf56 | 0.620809 | 3 | 0 | 3 |
| PPP5D1 | BEST1 | 0.612121 | 3 | 0 | 3 |
| PPP5D1 | NR4A3 | 0.589192 | 3 | 0 | 3 |
| PPP5D1 | SVEP1 | 0.581593 | 4 | 0 | 3 |
| PPP5D1 | DOCK1 | 0.572643 | 3 | 0 | 3 |
| PPP5D1 | SCRG1 | 0.562166 | 3 | 0 | 3 |
| PPP5D1 | PLCL1 | 0.559048 | 3 | 0 | 3 |
| PPP5D1 | ASB12 | 0.558142 | 3 | 0 | 3 |
| PPP5D1 | SYPL2 | 0.553022 | 4 | 0 | 3 |
| PPP5D1 | CCDC136 | 0.549431 | 3 | 0 | 3 |
| PPP5D1 | TBX5-AS1 | 0.547372 | 3 | 0 | 3 |
| PPP5D1 | SMIM10 | 0.545215 | 3 | 0 | 3 |
| PPP5D1 | MEOX2 | 0.543321 | 3 | 0 | 3 |
For details and further investigation, click here
