| Full name: chymotrypsin like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 1506 | HGNC ID: HGNC:2524 | Ensembl Gene: ENSG00000141086 | OMIM ID: 118888 |
| Drug and gene relationship at DGIdb | |||
Expression of CTRL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTRL | 1506 | 214377_s_at | 0.8216 | 0.0146 | |
| GSE20347 | CTRL | 1506 | 214377_s_at | 0.2167 | 0.0036 | |
| GSE23400 | CTRL | 1506 | 214377_s_at | 0.0392 | 0.2927 | |
| GSE26886 | CTRL | 1506 | 214377_s_at | 0.1071 | 0.3274 | |
| GSE29001 | CTRL | 1506 | 214377_s_at | -0.0112 | 0.9528 | |
| GSE38129 | CTRL | 1506 | 214377_s_at | 0.0587 | 0.5348 | |
| GSE45670 | CTRL | 1506 | 214377_s_at | 0.2029 | 0.0444 | |
| GSE53622 | CTRL | 1506 | 66748 | 0.5209 | 0.0000 | |
| GSE53624 | CTRL | 1506 | 66748 | 0.4914 | 0.0000 | |
| GSE63941 | CTRL | 1506 | 214377_s_at | 0.3373 | 0.0126 | |
| GSE77861 | CTRL | 1506 | 214377_s_at | 0.1014 | 0.5922 | |
| GSE97050 | CTRL | 1506 | A_24_P90900 | 0.2226 | 0.2813 | |
| SRP064894 | CTRL | 1506 | RNAseq | 1.0898 | 0.0001 | |
| SRP133303 | CTRL | 1506 | RNAseq | -0.2229 | 0.3679 | |
| SRP159526 | CTRL | 1506 | RNAseq | 1.3802 | 0.0492 | |
| SRP219564 | CTRL | 1506 | RNAseq | 0.4477 | 0.2837 | |
| TCGA | CTRL | 1506 | RNAseq | 0.0925 | 0.6528 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CTRL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTRL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTRL | 1506 | 9 | 2 | 19 | |
| GSE20123 | CTRL | 1506 | 9 | 2 | 19 | |
| GSE43470 | CTRL | 1506 | 1 | 9 | 33 | |
| GSE46452 | CTRL | 1506 | 38 | 1 | 20 | |
| GSE47630 | CTRL | 1506 | 11 | 8 | 21 | |
| GSE54993 | CTRL | 1506 | 2 | 4 | 64 | |
| GSE54994 | CTRL | 1506 | 8 | 10 | 35 | |
| GSE60625 | CTRL | 1506 | 4 | 0 | 7 | |
| GSE74703 | CTRL | 1506 | 1 | 6 | 29 | |
| GSE74704 | CTRL | 1506 | 5 | 1 | 14 | |
| TCGA | CTRL | 1506 | 30 | 12 | 54 |
Total number of gains: 118; Total number of losses: 55; Total Number of normals: 315.
Somatic mutations of CTRL:
Generating mutation plots.
Highly correlated genes for CTRL:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTRL | CLSTN3 | 0.703137 | 4 | 0 | 4 |
| CTRL | SCN1B | 0.691869 | 3 | 0 | 3 |
| CTRL | SHC2 | 0.689235 | 3 | 0 | 3 |
| CTRL | OR2H2 | 0.67351 | 3 | 0 | 3 |
| CTRL | ZDHHC8 | 0.667612 | 4 | 0 | 3 |
| CTRL | ELOVL3 | 0.665292 | 3 | 0 | 3 |
| CTRL | RFT1 | 0.664738 | 3 | 0 | 3 |
| CTRL | ADAMTS13 | 0.660296 | 3 | 0 | 3 |
| CTRL | SHISA7 | 0.655078 | 3 | 0 | 3 |
| CTRL | TBX21 | 0.65259 | 3 | 0 | 3 |
| CTRL | CENPB | 0.65161 | 5 | 0 | 4 |
| CTRL | PKM | 0.64964 | 4 | 0 | 4 |
| CTRL | HMBS | 0.649265 | 3 | 0 | 3 |
| CTRL | CEMP1 | 0.64465 | 3 | 0 | 3 |
| CTRL | RASSF7 | 0.642299 | 3 | 0 | 3 |
| CTRL | GPRIN1 | 0.6399 | 4 | 0 | 3 |
| CTRL | PFN1 | 0.639512 | 5 | 0 | 4 |
| CTRL | RIMS4 | 0.638463 | 4 | 0 | 4 |
| CTRL | FASTK | 0.638148 | 4 | 0 | 3 |
| CTRL | PNPLA2 | 0.635875 | 4 | 0 | 3 |
For details and further investigation, click here
