| Full name: centromere protein B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 1059 | HGNC ID: HGNC:1852 | Ensembl Gene: ENSG00000125817 | OMIM ID: 117140 |
Screen Evidence:
| |||
Expression of CENPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPB | 1059 | 212437_at | 0.5939 | 0.0378 | |
| GSE20347 | CENPB | 1059 | 212437_at | 0.1536 | 0.3046 | |
| GSE23400 | CENPB | 1059 | 212437_at | 0.1358 | 0.0389 | |
| GSE26886 | CENPB | 1059 | 212437_at | 0.4138 | 0.0339 | |
| GSE29001 | CENPB | 1059 | 212437_at | 0.0057 | 0.9785 | |
| GSE38129 | CENPB | 1059 | 212437_at | 0.0835 | 0.5512 | |
| GSE45670 | CENPB | 1059 | 212437_at | 0.1665 | 0.3306 | |
| GSE53622 | CENPB | 1059 | 69445 | 0.2443 | 0.0000 | |
| GSE53624 | CENPB | 1059 | 69445 | 0.5431 | 0.0000 | |
| GSE63941 | CENPB | 1059 | 212437_at | 1.0529 | 0.0122 | |
| GSE77861 | CENPB | 1059 | 212437_at | 0.3735 | 0.0441 | |
| GSE97050 | CENPB | 1059 | A_23_P257905 | 0.4244 | 0.3125 | |
| SRP007169 | CENPB | 1059 | RNAseq | -0.9110 | 0.0282 | |
| SRP008496 | CENPB | 1059 | RNAseq | -0.3340 | 0.2198 | |
| SRP064894 | CENPB | 1059 | RNAseq | 0.6798 | 0.0221 | |
| SRP133303 | CENPB | 1059 | RNAseq | 0.2016 | 0.1101 | |
| SRP159526 | CENPB | 1059 | RNAseq | 0.6242 | 0.0434 | |
| SRP193095 | CENPB | 1059 | RNAseq | 0.2242 | 0.1280 | |
| SRP219564 | CENPB | 1059 | RNAseq | -0.1831 | 0.6751 | |
| TCGA | CENPB | 1059 | RNAseq | 0.0059 | 0.8958 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CENPB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPB | 1059 | 12 | 3 | 15 | |
| GSE20123 | CENPB | 1059 | 13 | 3 | 14 | |
| GSE43470 | CENPB | 1059 | 10 | 1 | 32 | |
| GSE46452 | CENPB | 1059 | 26 | 1 | 32 | |
| GSE47630 | CENPB | 1059 | 18 | 4 | 18 | |
| GSE54993 | CENPB | 1059 | 2 | 14 | 54 | |
| GSE54994 | CENPB | 1059 | 22 | 3 | 28 | |
| GSE60625 | CENPB | 1059 | 0 | 0 | 11 | |
| GSE74703 | CENPB | 1059 | 9 | 1 | 26 | |
| GSE74704 | CENPB | 1059 | 8 | 1 | 11 | |
| TCGA | CENPB | 1059 | 39 | 11 | 46 |
Total number of gains: 159; Total number of losses: 42; Total Number of normals: 287.
Somatic mutations of CENPB:
Generating mutation plots.
Highly correlated genes for CENPB:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPB | CD276 | 0.708737 | 3 | 0 | 3 |
| CENPB | FAM89B | 0.689398 | 3 | 0 | 3 |
| CENPB | ZC3H18 | 0.683832 | 4 | 0 | 3 |
| CENPB | PLA2G7 | 0.6808 | 4 | 0 | 3 |
| CENPB | MBOAT7 | 0.65182 | 4 | 0 | 3 |
| CENPB | CTRL | 0.65161 | 5 | 0 | 4 |
| CENPB | TMC8 | 0.651132 | 3 | 0 | 3 |
| CENPB | IRF2BP2 | 0.650059 | 3 | 0 | 3 |
| CENPB | BCAM | 0.649208 | 4 | 0 | 3 |
| CENPB | IGFLR1 | 0.647541 | 3 | 0 | 3 |
| CENPB | HTRA3 | 0.646186 | 4 | 0 | 3 |
| CENPB | TP53I13 | 0.644237 | 5 | 0 | 3 |
| CENPB | CD320 | 0.642172 | 3 | 0 | 3 |
| CENPB | NCAPH | 0.641964 | 3 | 0 | 3 |
| CENPB | TAGLN2 | 0.639676 | 4 | 0 | 3 |
| CENPB | SLC7A5 | 0.635912 | 4 | 0 | 4 |
| CENPB | SAMD1 | 0.632616 | 5 | 0 | 5 |
| CENPB | SOX13 | 0.631144 | 4 | 0 | 4 |
| CENPB | TFEB | 0.627714 | 3 | 0 | 3 |
| CENPB | ANKRD52 | 0.626121 | 4 | 0 | 4 |
For details and further investigation, click here
