CXCL13

 

Full name: C-X-C motif chemokine ligand 13 Alias Symbol: BLC|BCA-1|BLR1L|ANGIE|ANGIE2
Type: protein-coding gene Cytoband: 4q21.1
Entrez ID: 10563 HGNC ID: HGNC:10639 Ensembl Gene: ENSG00000156234 OMIM ID: 605149
Drug and gene relationship at DGIdb

 

CXCL13 involved pathways:

KEGG pathway Description View
hsa04062Chemokine signaling pathway

 

Expression of CXCL13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CXCL13 10563 205242_at 0.8112 0.7233
GSE20347 CXCL13 10563 205242_at 1.3325 0.0445
GSE23400 CXCL13 10563 205242_at 0.7096 0.0083
GSE26886 CXCL13 10563 205242_at 0.7106 0.2620
GSE29001 CXCL13 10563 205242_at 2.7363 0.0006
GSE38129 CXCL13 10563 205242_at 1.5328 0.0128
GSE45670 CXCL13 10563 205242_at 2.6597 0.0019
GSE53622 CXCL13 10563 14622 1.2981 0.0003
GSE53624 CXCL13 10563 14622 0.2421 0.4360
GSE63941 CXCL13 10563 205242_at 0.2542 0.0101
GSE77861 CXCL13 10563 205242_at 1.2885 0.0974
GSE97050 CXCL13 10563 A_23_P121695 2.2370 0.1299
SRP007169 CXCL13 10563 RNAseq 3.6652 0.0037
SRP133303 CXCL13 10563 RNAseq 1.0032 0.2198
SRP159526 CXCL13 10563 RNAseq -0.8510 0.4607
SRP219564 CXCL13 10563 RNAseq 2.6080 0.0044
TCGA CXCL13 10563 RNAseq 0.7670 0.0122

Upregulated datasets: 7; Downregulated datasets: 0.  

 

Survival by CXCL13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CXCL13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CXCL13 10563 2 9 19
GSE20123 CXCL13 10563 2 9 19
GSE43470 CXCL13 10563 1 12 30
GSE46452 CXCL13 10563 1 36 22
GSE47630 CXCL13 10563 1 19 20
GSE54993 CXCL13 10563 7 0 63
GSE54994 CXCL13 10563 0 9 44
GSE60625 CXCL13 10563 0 0 11
GSE74703 CXCL13 10563 1 10 25
GSE74704 CXCL13 10563 2 5 13
TCGA CXCL13 10563 14 32 50

Total number of gains: 31; Total number of losses: 141; Total Number of normals: 316.  

 

Somatic mutations of CXCL13:

 

Generating mutation plots.

 

Highly correlated genes for CXCL13:

 

Showing top 20/588 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CXCL13SLAMF60.761097505
CXCL13ZC3H12D0.751188505
CXCL13FCRL30.740742606
CXCL13SNX200.731292404
CXCL13SP1400.719032303
CXCL13SPCS30.718053303
CXCL13CD370.713488808
CXCL13ZNF5810.703064303
CXCL13UBASH3A0.700339403
CXCL13SUSD30.69844606
CXCL13OPA10.693078303
CXCL13CDCA20.691552303
CXCL13STEAP1B0.68987303
CXCL13PARVG0.68741605
CXCL13CD530.685149908
CXCL13BTLA0.684789505
CXCL13CD2260.683259403
CXCL13SIRPG0.678218808
CXCL13CYTIP0.677398908
CXCL13NDC800.675849504

For details and further investigation, click here