| Full name: STEAP family member 1B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 256227 | HGNC ID: HGNC:41907 | Ensembl Gene: ENSG00000105889 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of STEAP1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STEAP1B | 256227 | 217553_at | 1.8629 | 0.2302 | |
| GSE20347 | STEAP1B | 256227 | 217553_at | 1.2186 | 0.0010 | |
| GSE23400 | STEAP1B | 256227 | 217553_at | 0.4775 | 0.0000 | |
| GSE26886 | STEAP1B | 256227 | 217553_at | 1.5426 | 0.0050 | |
| GSE29001 | STEAP1B | 256227 | 217553_at | 1.9876 | 0.0003 | |
| GSE38129 | STEAP1B | 256227 | 217553_at | 1.2035 | 0.0001 | |
| GSE45670 | STEAP1B | 256227 | 217553_at | 1.6710 | 0.0027 | |
| GSE63941 | STEAP1B | 256227 | 217553_at | -1.1506 | 0.3277 | |
| GSE77861 | STEAP1B | 256227 | 217553_at | 0.2002 | 0.5619 | |
| GSE97050 | STEAP1B | A_21_P0000044 | 1.7038 | 0.0750 | ||
| SRP064894 | STEAP1B | 256227 | RNAseq | 3.3535 | 0.0000 | |
| SRP133303 | STEAP1B | 256227 | RNAseq | 4.1519 | 0.0000 | |
| SRP159526 | STEAP1B | 256227 | RNAseq | 3.9682 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Copy number change of STEAP1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STEAP1B | 256227 | 17 | 1 | 12 | |
| GSE20123 | STEAP1B | 256227 | 17 | 1 | 12 | |
| GSE43470 | STEAP1B | 256227 | 4 | 0 | 39 | |
| GSE46452 | STEAP1B | 256227 | 10 | 2 | 47 | |
| GSE47630 | STEAP1B | 256227 | 9 | 1 | 30 | |
| GSE54993 | STEAP1B | 256227 | 0 | 6 | 64 | |
| GSE54994 | STEAP1B | 256227 | 20 | 2 | 31 | |
| GSE60625 | STEAP1B | 256227 | 0 | 0 | 11 | |
| GSE74703 | STEAP1B | 256227 | 4 | 0 | 32 | |
| GSE74704 | STEAP1B | 256227 | 11 | 1 | 8 | |
| TCGA | STEAP1B | 256227 | 56 | 4 | 36 |
Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.
Somatic mutations of STEAP1B:
Generating mutation plots.
Highly correlated genes for STEAP1B:
Showing top 20/857 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STEAP1B | CDCA2 | 0.773054 | 3 | 0 | 3 |
| STEAP1B | XPR1 | 0.772165 | 4 | 0 | 4 |
| STEAP1B | AMIGO2 | 0.769204 | 5 | 0 | 5 |
| STEAP1B | BIRC2 | 0.762657 | 4 | 0 | 4 |
| STEAP1B | UBA6 | 0.74543 | 3 | 0 | 3 |
| STEAP1B | CYB5R1 | 0.741928 | 3 | 0 | 3 |
| STEAP1B | NUDT5 | 0.741491 | 4 | 0 | 4 |
| STEAP1B | ZDHHC24 | 0.738216 | 3 | 0 | 3 |
| STEAP1B | PCSK1 | 0.733663 | 3 | 0 | 3 |
| STEAP1B | UBTD2 | 0.733633 | 3 | 0 | 3 |
| STEAP1B | KANK4 | 0.729423 | 3 | 0 | 3 |
| STEAP1B | EME1 | 0.729099 | 4 | 0 | 4 |
| STEAP1B | CCDC86 | 0.726694 | 7 | 0 | 7 |
| STEAP1B | C16orf74 | 0.726252 | 4 | 0 | 4 |
| STEAP1B | CYP27C1 | 0.726013 | 4 | 0 | 3 |
| STEAP1B | SET | 0.722034 | 3 | 0 | 3 |
| STEAP1B | ACP2 | 0.717612 | 3 | 0 | 3 |
| STEAP1B | CPT1C | 0.714437 | 3 | 0 | 3 |
| STEAP1B | MRPL32 | 0.714288 | 4 | 0 | 4 |
| STEAP1B | TPCN2 | 0.713372 | 3 | 0 | 3 |
For details and further investigation, click here
