| Full name: methionine sulfoxide reductase B1 | Alias Symbol: SelR|SepR|SelX | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 51734 | HGNC ID: HGNC:14133 | Ensembl Gene: ENSG00000198736 | OMIM ID: 606216 |
| Drug and gene relationship at DGIdb | |||
Expression of MSRB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSRB1 | 51734 | 217977_at | 0.6622 | 0.1634 | |
| GSE20347 | MSRB1 | 51734 | 217977_at | 0.3157 | 0.0705 | |
| GSE23400 | MSRB1 | 51734 | 217977_at | 0.1423 | 0.0484 | |
| GSE26886 | MSRB1 | 51734 | 217977_at | -0.1631 | 0.6091 | |
| GSE29001 | MSRB1 | 51734 | 217977_at | 0.3142 | 0.2860 | |
| GSE38129 | MSRB1 | 51734 | 217977_at | 0.1688 | 0.4460 | |
| GSE45670 | MSRB1 | 51734 | 217977_at | 0.6548 | 0.0004 | |
| GSE53622 | MSRB1 | 51734 | 124323 | 0.1231 | 0.3969 | |
| GSE53624 | MSRB1 | 51734 | 124323 | 0.2245 | 0.0189 | |
| GSE63941 | MSRB1 | 51734 | 217977_at | -0.0193 | 0.9765 | |
| GSE77861 | MSRB1 | 51734 | 217977_at | 0.5186 | 0.0625 | |
| SRP007169 | MSRB1 | 51734 | RNAseq | -0.6830 | 0.0767 | |
| SRP008496 | MSRB1 | 51734 | RNAseq | -0.6453 | 0.0270 | |
| SRP064894 | MSRB1 | 51734 | RNAseq | 0.0633 | 0.8135 | |
| SRP133303 | MSRB1 | 51734 | RNAseq | 0.7871 | 0.0161 | |
| SRP159526 | MSRB1 | 51734 | RNAseq | -0.2768 | 0.5450 | |
| SRP193095 | MSRB1 | 51734 | RNAseq | 0.6693 | 0.0001 | |
| SRP219564 | MSRB1 | 51734 | RNAseq | 0.5124 | 0.3521 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MSRB1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MSRB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MSRB1 | 51734 | 5 | 5 | 20 | |
| GSE20123 | MSRB1 | 51734 | 5 | 4 | 21 | |
| GSE43470 | MSRB1 | 51734 | 4 | 7 | 32 | |
| GSE46452 | MSRB1 | 51734 | 38 | 1 | 20 | |
| GSE47630 | MSRB1 | 51734 | 13 | 6 | 21 | |
| GSE54993 | MSRB1 | 51734 | 3 | 5 | 62 | |
| GSE54994 | MSRB1 | 51734 | 5 | 9 | 39 | |
| GSE60625 | MSRB1 | 51734 | 4 | 0 | 7 | |
| GSE74703 | MSRB1 | 51734 | 4 | 5 | 27 | |
| GSE74704 | MSRB1 | 51734 | 3 | 2 | 15 | |
| TCGA | MSRB1 | 51734 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of MSRB1:
Generating mutation plots.
Highly correlated genes for MSRB1:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSRB1 | CYP27C1 | 0.796399 | 3 | 0 | 3 |
| MSRB1 | WDR66 | 0.712408 | 3 | 0 | 3 |
| MSRB1 | SLC2A1 | 0.697864 | 4 | 0 | 3 |
| MSRB1 | ZNF114 | 0.691301 | 3 | 0 | 3 |
| MSRB1 | NMB | 0.664859 | 5 | 0 | 4 |
| MSRB1 | KRT75 | 0.662469 | 3 | 0 | 3 |
| MSRB1 | GPR153 | 0.65908 | 4 | 0 | 4 |
| MSRB1 | FBLIM1 | 0.658095 | 3 | 0 | 3 |
| MSRB1 | COPA | 0.65539 | 3 | 0 | 3 |
| MSRB1 | FSCN1 | 0.652622 | 5 | 0 | 5 |
| MSRB1 | SLC22A4 | 0.648102 | 4 | 0 | 3 |
| MSRB1 | TTYH3 | 0.645724 | 4 | 0 | 3 |
| MSRB1 | CDC20 | 0.645376 | 4 | 0 | 3 |
| MSRB1 | TSPAN10 | 0.644179 | 3 | 0 | 3 |
| MSRB1 | PSMA4 | 0.64416 | 3 | 0 | 3 |
| MSRB1 | EME1 | 0.64384 | 3 | 0 | 3 |
| MSRB1 | TANC2 | 0.634695 | 5 | 0 | 4 |
| MSRB1 | MED9 | 0.631527 | 3 | 0 | 3 |
| MSRB1 | LAPTM4B | 0.626776 | 3 | 0 | 3 |
| MSRB1 | HSD17B2 | 0.625462 | 3 | 0 | 3 |
For details and further investigation, click here
