| Full name: DNA cross-link repair 1A | Alias Symbol: SNM1|PSO2|KIAA0086|hSNM1 | ||
| Type: protein-coding gene | Cytoband: 10q25.3 | ||
| Entrez ID: 9937 | HGNC ID: HGNC:17660 | Ensembl Gene: ENSG00000198924 | OMIM ID: 609682 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DCLRE1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCLRE1A | 9937 | 209804_at | 0.8354 | 0.1126 | |
| GSE20347 | DCLRE1A | 9937 | 209804_at | 0.5290 | 0.0000 | |
| GSE23400 | DCLRE1A | 9937 | 209804_at | 0.1376 | 0.0002 | |
| GSE26886 | DCLRE1A | 9937 | 209804_at | 0.5273 | 0.0166 | |
| GSE29001 | DCLRE1A | 9937 | 209804_at | 0.3812 | 0.1759 | |
| GSE38129 | DCLRE1A | 9937 | 209804_at | 0.5578 | 0.0000 | |
| GSE45670 | DCLRE1A | 9937 | 209804_at | 0.4470 | 0.0047 | |
| GSE53622 | DCLRE1A | 9937 | 97439 | 0.3267 | 0.0033 | |
| GSE53624 | DCLRE1A | 9937 | 97439 | 0.6779 | 0.0000 | |
| GSE63941 | DCLRE1A | 9937 | 209804_at | 0.8513 | 0.0306 | |
| GSE77861 | DCLRE1A | 9937 | 209804_at | 0.2767 | 0.0427 | |
| GSE97050 | DCLRE1A | 9937 | A_23_P75038 | 0.1455 | 0.6893 | |
| SRP007169 | DCLRE1A | 9937 | RNAseq | 0.5506 | 0.2391 | |
| SRP008496 | DCLRE1A | 9937 | RNAseq | 0.9176 | 0.0135 | |
| SRP064894 | DCLRE1A | 9937 | RNAseq | 0.0003 | 0.9986 | |
| SRP133303 | DCLRE1A | 9937 | RNAseq | 0.7941 | 0.0003 | |
| SRP159526 | DCLRE1A | 9937 | RNAseq | 0.4463 | 0.2276 | |
| SRP193095 | DCLRE1A | 9937 | RNAseq | 0.4675 | 0.0000 | |
| SRP219564 | DCLRE1A | 9937 | RNAseq | 0.2717 | 0.4976 | |
| TCGA | DCLRE1A | 9937 | RNAseq | 0.0237 | 0.7057 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCLRE1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCLRE1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCLRE1A | 9937 | 1 | 8 | 21 | |
| GSE20123 | DCLRE1A | 9937 | 1 | 7 | 22 | |
| GSE43470 | DCLRE1A | 9937 | 0 | 9 | 34 | |
| GSE46452 | DCLRE1A | 9937 | 0 | 11 | 48 | |
| GSE47630 | DCLRE1A | 9937 | 2 | 14 | 24 | |
| GSE54993 | DCLRE1A | 9937 | 8 | 0 | 62 | |
| GSE54994 | DCLRE1A | 9937 | 1 | 10 | 42 | |
| GSE60625 | DCLRE1A | 9937 | 0 | 0 | 11 | |
| GSE74703 | DCLRE1A | 9937 | 0 | 6 | 30 | |
| GSE74704 | DCLRE1A | 9937 | 1 | 3 | 16 | |
| TCGA | DCLRE1A | 9937 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of DCLRE1A:
Generating mutation plots.
Highly correlated genes for DCLRE1A:
Showing top 20/940 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCLRE1A | LRRC58 | 0.736177 | 4 | 0 | 4 |
| DCLRE1A | ALG1 | 0.72676 | 3 | 0 | 3 |
| DCLRE1A | HPS3 | 0.722452 | 4 | 0 | 4 |
| DCLRE1A | USP34 | 0.702943 | 3 | 0 | 3 |
| DCLRE1A | SAMD12 | 0.686852 | 3 | 0 | 3 |
| DCLRE1A | ZFP69 | 0.679752 | 5 | 0 | 5 |
| DCLRE1A | NCBP2 | 0.664548 | 7 | 0 | 6 |
| DCLRE1A | RPS29 | 0.664013 | 3 | 0 | 3 |
| DCLRE1A | FBXO45 | 0.657303 | 3 | 0 | 3 |
| DCLRE1A | UBE2J2 | 0.653635 | 3 | 0 | 3 |
| DCLRE1A | MTFR2 | 0.651293 | 5 | 0 | 5 |
| DCLRE1A | ACVR1C | 0.647055 | 3 | 0 | 3 |
| DCLRE1A | TBCCD1 | 0.646851 | 8 | 0 | 7 |
| DCLRE1A | EME1 | 0.646263 | 4 | 0 | 4 |
| DCLRE1A | CHP2 | 0.645379 | 3 | 0 | 3 |
| DCLRE1A | ZSCAN25 | 0.644974 | 4 | 0 | 4 |
| DCLRE1A | THNSL1 | 0.643784 | 11 | 0 | 9 |
| DCLRE1A | C1orf112 | 0.643417 | 9 | 0 | 8 |
| DCLRE1A | TRUB1 | 0.643096 | 5 | 0 | 4 |
| DCLRE1A | TMEM209 | 0.642825 | 8 | 0 | 6 |
For details and further investigation, click here
