| Full name: D-aspartate oxidase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 8528 | HGNC ID: HGNC:2727 | Ensembl Gene: ENSG00000203797 | OMIM ID: 124450 |
| Drug and gene relationship at DGIdb | |||
Expression of DDO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDO | 8528 | 207418_s_at | -0.0461 | 0.9044 | |
| GSE20347 | DDO | 8528 | 207418_s_at | -0.0112 | 0.8819 | |
| GSE23400 | DDO | 8528 | 207418_s_at | -0.2182 | 0.0000 | |
| GSE26886 | DDO | 8528 | 207418_s_at | 0.1200 | 0.1691 | |
| GSE29001 | DDO | 8528 | 222134_at | 0.1316 | 0.5067 | |
| GSE38129 | DDO | 8528 | 207418_s_at | -0.0461 | 0.4342 | |
| GSE45670 | DDO | 8528 | 207418_s_at | -0.0871 | 0.3613 | |
| GSE53622 | DDO | 8528 | 113175 | -0.3778 | 0.0060 | |
| GSE53624 | DDO | 8528 | 113175 | -0.4023 | 0.0001 | |
| GSE63941 | DDO | 8528 | 207418_s_at | 0.0823 | 0.7430 | |
| GSE77861 | DDO | 8528 | 207418_s_at | -0.0301 | 0.7972 | |
| SRP064894 | DDO | 8528 | RNAseq | -0.2549 | 0.3781 | |
| SRP133303 | DDO | 8528 | RNAseq | 0.3959 | 0.3581 | |
| SRP159526 | DDO | 8528 | RNAseq | -0.0962 | 0.9144 | |
| SRP219564 | DDO | 8528 | RNAseq | -0.3488 | 0.4937 | |
| TCGA | DDO | 8528 | RNAseq | -0.6917 | 0.1284 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDO | 8528 | 2 | 3 | 25 | |
| GSE20123 | DDO | 8528 | 2 | 2 | 26 | |
| GSE43470 | DDO | 8528 | 3 | 1 | 39 | |
| GSE46452 | DDO | 8528 | 2 | 11 | 46 | |
| GSE47630 | DDO | 8528 | 9 | 4 | 27 | |
| GSE54993 | DDO | 8528 | 3 | 2 | 65 | |
| GSE54994 | DDO | 8528 | 8 | 8 | 37 | |
| GSE60625 | DDO | 8528 | 0 | 2 | 9 | |
| GSE74703 | DDO | 8528 | 2 | 1 | 33 | |
| GSE74704 | DDO | 8528 | 0 | 0 | 20 | |
| TCGA | DDO | 8528 | 6 | 23 | 67 |
Total number of gains: 37; Total number of losses: 57; Total Number of normals: 394.
Somatic mutations of DDO:
Generating mutation plots.
Highly correlated genes for DDO:
Showing top 20/114 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDO | CP | 0.684987 | 3 | 0 | 3 |
| DDO | PNMA2 | 0.668746 | 3 | 0 | 3 |
| DDO | PYGO1 | 0.654342 | 4 | 0 | 3 |
| DDO | DNAJC12 | 0.630979 | 4 | 0 | 3 |
| DDO | LRRD1 | 0.621248 | 3 | 0 | 3 |
| DDO | ZMYND10 | 0.619327 | 4 | 0 | 4 |
| DDO | VENTX | 0.612864 | 3 | 0 | 3 |
| DDO | SARDH | 0.610761 | 4 | 0 | 3 |
| DDO | OPRD1 | 0.610089 | 4 | 0 | 3 |
| DDO | AFF3 | 0.609315 | 3 | 0 | 3 |
| DDO | ISYNA1 | 0.608691 | 3 | 0 | 3 |
| DDO | REN | 0.608137 | 3 | 0 | 3 |
| DDO | NCR1 | 0.603012 | 4 | 0 | 3 |
| DDO | KCNJ4 | 0.600105 | 4 | 0 | 3 |
| DDO | KRT3 | 0.597577 | 5 | 0 | 4 |
| DDO | CDK20 | 0.597282 | 3 | 0 | 3 |
| DDO | SYT13 | 0.592407 | 3 | 0 | 3 |
| DDO | CITED1 | 0.588586 | 4 | 0 | 3 |
| DDO | GAL3ST1 | 0.586722 | 5 | 0 | 4 |
| DDO | CACNA1H | 0.585515 | 4 | 0 | 3 |
For details and further investigation, click here
