| Full name: DEAH-box helicase 15 | Alias Symbol: HRH2|DBP1|PRP43|PrPp43p|PRPF43 | ||
| Type: protein-coding gene | Cytoband: 4p15.2 | ||
| Entrez ID: 1665 | HGNC ID: HGNC:2738 | Ensembl Gene: ENSG00000109606 | OMIM ID: 603403 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX15 | 1665 | 201385_at | 0.2476 | 0.4534 | |
| GSE20347 | DHX15 | 1665 | 201385_at | 0.2369 | 0.0159 | |
| GSE23400 | DHX15 | 1665 | 201385_at | 0.2786 | 0.0000 | |
| GSE26886 | DHX15 | 1665 | 201385_at | -0.3692 | 0.0133 | |
| GSE29001 | DHX15 | 1665 | 201385_at | 0.3148 | 0.0677 | |
| GSE38129 | DHX15 | 1665 | 201385_at | 0.3011 | 0.0015 | |
| GSE45670 | DHX15 | 1665 | 201385_at | 0.0790 | 0.2925 | |
| GSE53622 | DHX15 | 1665 | 149463 | 0.3321 | 0.0000 | |
| GSE53624 | DHX15 | 1665 | 149463 | 0.1248 | 0.0356 | |
| GSE63941 | DHX15 | 1665 | 201385_at | 0.0756 | 0.7401 | |
| GSE77861 | DHX15 | 1665 | 201385_at | 0.1218 | 0.4471 | |
| GSE97050 | DHX15 | 1665 | A_23_P69826 | 0.3159 | 0.2569 | |
| SRP007169 | DHX15 | 1665 | RNAseq | 0.0894 | 0.8382 | |
| SRP008496 | DHX15 | 1665 | RNAseq | -0.0645 | 0.7822 | |
| SRP064894 | DHX15 | 1665 | RNAseq | -0.0112 | 0.9536 | |
| SRP133303 | DHX15 | 1665 | RNAseq | 0.0408 | 0.6760 | |
| SRP159526 | DHX15 | 1665 | RNAseq | -0.0870 | 0.7147 | |
| SRP193095 | DHX15 | 1665 | RNAseq | -0.1123 | 0.1300 | |
| SRP219564 | DHX15 | 1665 | RNAseq | -0.2662 | 0.2855 | |
| TCGA | DHX15 | 1665 | RNAseq | 0.0129 | 0.7592 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DHX15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX15 | 1665 | 0 | 18 | 12 | |
| GSE20123 | DHX15 | 1665 | 0 | 16 | 14 | |
| GSE43470 | DHX15 | 1665 | 0 | 15 | 28 | |
| GSE46452 | DHX15 | 1665 | 1 | 36 | 22 | |
| GSE47630 | DHX15 | 1665 | 1 | 19 | 20 | |
| GSE54993 | DHX15 | 1665 | 10 | 0 | 60 | |
| GSE54994 | DHX15 | 1665 | 5 | 11 | 37 | |
| GSE60625 | DHX15 | 1665 | 0 | 0 | 11 | |
| GSE74703 | DHX15 | 1665 | 0 | 13 | 23 | |
| GSE74704 | DHX15 | 1665 | 0 | 10 | 10 | |
| TCGA | DHX15 | 1665 | 11 | 47 | 38 |
Total number of gains: 28; Total number of losses: 185; Total Number of normals: 275.
Somatic mutations of DHX15:
Generating mutation plots.
Highly correlated genes for DHX15:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX15 | SCOC | 0.788589 | 3 | 0 | 3 |
| DHX15 | TRIM35 | 0.763942 | 3 | 0 | 3 |
| DHX15 | CTBS | 0.750805 | 3 | 0 | 3 |
| DHX15 | PI4K2B | 0.743288 | 3 | 0 | 3 |
| DHX15 | RAB11FIP2 | 0.739686 | 3 | 0 | 3 |
| DHX15 | CRLS1 | 0.725935 | 3 | 0 | 3 |
| DHX15 | INTS10 | 0.719226 | 4 | 0 | 4 |
| DHX15 | PDXDC1 | 0.711997 | 3 | 0 | 3 |
| DHX15 | KIAA1586 | 0.711718 | 3 | 0 | 3 |
| DHX15 | ELF2 | 0.702414 | 4 | 0 | 4 |
| DHX15 | RELL1 | 0.696946 | 4 | 0 | 4 |
| DHX15 | HIF1A | 0.69555 | 4 | 0 | 4 |
| DHX15 | HNRNPR | 0.693176 | 8 | 0 | 8 |
| DHX15 | ACSL3 | 0.692056 | 3 | 0 | 3 |
| DHX15 | ALDH7A1 | 0.691955 | 3 | 0 | 3 |
| DHX15 | MRPS5 | 0.68896 | 3 | 0 | 3 |
| DHX15 | TM2D2 | 0.687873 | 3 | 0 | 3 |
| DHX15 | SEL1L | 0.686676 | 4 | 0 | 3 |
| DHX15 | ORC2 | 0.685831 | 4 | 0 | 4 |
| DHX15 | PCID2 | 0.685603 | 4 | 0 | 3 |
For details and further investigation, click here
