| Full name: death inducer-obliterator 1 | Alias Symbol: DIO1|dJ885L7.8|FLJ11265|KIAA0333|DIO-1|BYE1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 11083 | HGNC ID: HGNC:2680 | Ensembl Gene: ENSG00000101191 | OMIM ID: 604140 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DIDO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DIDO1 | 11083 | 218325_s_at | 0.0062 | 0.9948 | |
| GSE20347 | DIDO1 | 11083 | 218325_s_at | -0.3926 | 0.0413 | |
| GSE23400 | DIDO1 | 11083 | 218325_s_at | -0.1991 | 0.0014 | |
| GSE26886 | DIDO1 | 11083 | 218325_s_at | -0.6394 | 0.0152 | |
| GSE29001 | DIDO1 | 11083 | 218325_s_at | 0.0147 | 0.9672 | |
| GSE38129 | DIDO1 | 11083 | 218325_s_at | -0.4720 | 0.0054 | |
| GSE45670 | DIDO1 | 11083 | 218325_s_at | -0.6757 | 0.0009 | |
| GSE53622 | DIDO1 | 11083 | 81960 | 0.0005 | 0.9940 | |
| GSE53624 | DIDO1 | 11083 | 81960 | -0.1076 | 0.0779 | |
| GSE63941 | DIDO1 | 11083 | 218325_s_at | 0.5275 | 0.5465 | |
| GSE77861 | DIDO1 | 11083 | 218325_s_at | -0.2607 | 0.4175 | |
| GSE97050 | DIDO1 | 11083 | A_23_P395426 | -0.0924 | 0.6886 | |
| SRP007169 | DIDO1 | 11083 | RNAseq | -0.0124 | 0.9762 | |
| SRP008496 | DIDO1 | 11083 | RNAseq | -0.1088 | 0.6455 | |
| SRP064894 | DIDO1 | 11083 | RNAseq | -0.3685 | 0.0288 | |
| SRP133303 | DIDO1 | 11083 | RNAseq | 0.0030 | 0.9762 | |
| SRP159526 | DIDO1 | 11083 | RNAseq | -0.0754 | 0.8457 | |
| SRP193095 | DIDO1 | 11083 | RNAseq | 0.0898 | 0.3543 | |
| SRP219564 | DIDO1 | 11083 | RNAseq | 0.0971 | 0.7232 | |
| TCGA | DIDO1 | 11083 | RNAseq | -0.0444 | 0.3064 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DIDO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DIDO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DIDO1 | 11083 | 14 | 2 | 14 | |
| GSE20123 | DIDO1 | 11083 | 14 | 2 | 14 | |
| GSE43470 | DIDO1 | 11083 | 11 | 1 | 31 | |
| GSE46452 | DIDO1 | 11083 | 35 | 0 | 24 | |
| GSE47630 | DIDO1 | 11083 | 25 | 1 | 14 | |
| GSE54993 | DIDO1 | 11083 | 0 | 16 | 54 | |
| GSE54994 | DIDO1 | 11083 | 29 | 0 | 24 | |
| GSE60625 | DIDO1 | 11083 | 0 | 0 | 11 | |
| GSE74703 | DIDO1 | 11083 | 10 | 0 | 26 | |
| GSE74704 | DIDO1 | 11083 | 11 | 0 | 9 | |
| TCGA | DIDO1 | 11083 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 26; Total Number of normals: 269.
Somatic mutations of DIDO1:
Generating mutation plots.
Highly correlated genes for DIDO1:
Showing top 20/276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DIDO1 | ITPRIPL2 | 0.735119 | 3 | 0 | 3 |
| DIDO1 | C16orf46 | 0.710541 | 3 | 0 | 3 |
| DIDO1 | ANKRD27 | 0.706632 | 3 | 0 | 3 |
| DIDO1 | DPM1 | 0.703618 | 3 | 0 | 3 |
| DIDO1 | ZNF836 | 0.684524 | 3 | 0 | 3 |
| DIDO1 | WASF3 | 0.668734 | 4 | 0 | 4 |
| DIDO1 | OGFRL1 | 0.666987 | 3 | 0 | 3 |
| DIDO1 | TMEM167B | 0.665743 | 3 | 0 | 3 |
| DIDO1 | PPP2CB | 0.665504 | 3 | 0 | 3 |
| DIDO1 | PRPSAP1 | 0.664746 | 3 | 0 | 3 |
| DIDO1 | ZNF383 | 0.664316 | 3 | 0 | 3 |
| DIDO1 | SPATA18 | 0.66395 | 3 | 0 | 3 |
| DIDO1 | C7 | 0.659598 | 3 | 0 | 3 |
| DIDO1 | PAIP2 | 0.656414 | 3 | 0 | 3 |
| DIDO1 | GOLPH3 | 0.656394 | 3 | 0 | 3 |
| DIDO1 | AZIN1 | 0.655452 | 3 | 0 | 3 |
| DIDO1 | CASQ2 | 0.655345 | 4 | 0 | 4 |
| DIDO1 | TIFA | 0.654206 | 3 | 0 | 3 |
| DIDO1 | GNAQ | 0.653345 | 3 | 0 | 3 |
| DIDO1 | PHYHD1 | 0.65191 | 3 | 0 | 3 |
For details and further investigation, click here
