| Full name: opioid growth factor receptor like 1 | Alias Symbol: dJ331H24.1 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 79627 | HGNC ID: HGNC:21378 | Ensembl Gene: ENSG00000119900 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of OGFRL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OGFRL1 | 79627 | 226810_at | -0.5963 | 0.2354 | |
| GSE20347 | OGFRL1 | 79627 | 219582_at | -0.8651 | 0.0000 | |
| GSE23400 | OGFRL1 | 79627 | 219582_at | -0.3331 | 0.0000 | |
| GSE26886 | OGFRL1 | 79627 | 226810_at | -2.1002 | 0.0000 | |
| GSE29001 | OGFRL1 | 79627 | 219582_at | -0.8690 | 0.0075 | |
| GSE38129 | OGFRL1 | 79627 | 219582_at | -0.5248 | 0.0327 | |
| GSE45670 | OGFRL1 | 79627 | 226810_at | -1.3028 | 0.0005 | |
| GSE53622 | OGFRL1 | 79627 | 65437 | -1.3496 | 0.0000 | |
| GSE53624 | OGFRL1 | 79627 | 65437 | -1.1512 | 0.0000 | |
| GSE63941 | OGFRL1 | 79627 | 226810_at | -2.4443 | 0.0113 | |
| GSE77861 | OGFRL1 | 79627 | 226810_at | -1.0919 | 0.1387 | |
| GSE97050 | OGFRL1 | 79627 | A_23_P7791 | -0.7301 | 0.2061 | |
| SRP007169 | OGFRL1 | 79627 | RNAseq | -1.4561 | 0.0000 | |
| SRP008496 | OGFRL1 | 79627 | RNAseq | -1.4560 | 0.0000 | |
| SRP064894 | OGFRL1 | 79627 | RNAseq | -1.3152 | 0.0000 | |
| SRP133303 | OGFRL1 | 79627 | RNAseq | -1.1250 | 0.0000 | |
| SRP159526 | OGFRL1 | 79627 | RNAseq | -0.8919 | 0.0889 | |
| SRP193095 | OGFRL1 | 79627 | RNAseq | -1.3027 | 0.0000 | |
| SRP219564 | OGFRL1 | 79627 | RNAseq | -1.3134 | 0.0121 | |
| TCGA | OGFRL1 | 79627 | RNAseq | 0.1351 | 0.0989 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by OGFRL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OGFRL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OGFRL1 | 79627 | 2 | 2 | 26 | |
| GSE20123 | OGFRL1 | 79627 | 2 | 1 | 27 | |
| GSE43470 | OGFRL1 | 79627 | 3 | 0 | 40 | |
| GSE46452 | OGFRL1 | 79627 | 2 | 11 | 46 | |
| GSE47630 | OGFRL1 | 79627 | 8 | 4 | 28 | |
| GSE54993 | OGFRL1 | 79627 | 3 | 2 | 65 | |
| GSE54994 | OGFRL1 | 79627 | 9 | 5 | 39 | |
| GSE60625 | OGFRL1 | 79627 | 0 | 2 | 9 | |
| GSE74703 | OGFRL1 | 79627 | 3 | 0 | 33 | |
| GSE74704 | OGFRL1 | 79627 | 0 | 1 | 19 | |
| TCGA | OGFRL1 | 79627 | 10 | 20 | 66 |
Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.
Somatic mutations of OGFRL1:
Generating mutation plots.
Highly correlated genes for OGFRL1:
Showing top 20/1451 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OGFRL1 | CA13 | 0.80568 | 3 | 0 | 3 |
| OGFRL1 | USP9Y | 0.774984 | 3 | 0 | 3 |
| OGFRL1 | RBM20 | 0.758851 | 5 | 0 | 5 |
| OGFRL1 | ZNF564 | 0.756596 | 3 | 0 | 3 |
| OGFRL1 | RAB10 | 0.748378 | 4 | 0 | 4 |
| OGFRL1 | CASC3 | 0.741689 | 3 | 0 | 3 |
| OGFRL1 | FAM3B | 0.73951 | 5 | 0 | 5 |
| OGFRL1 | SENP8 | 0.738262 | 3 | 0 | 3 |
| OGFRL1 | ESYT2 | 0.731414 | 3 | 0 | 3 |
| OGFRL1 | SLC12A6 | 0.729834 | 8 | 0 | 8 |
| OGFRL1 | SRSF8 | 0.729366 | 3 | 0 | 3 |
| OGFRL1 | RBM7 | 0.72928 | 4 | 0 | 3 |
| OGFRL1 | C18orf25 | 0.72835 | 10 | 0 | 10 |
| OGFRL1 | SLC16A6 | 0.724516 | 12 | 0 | 12 |
| OGFRL1 | USP6NL | 0.723451 | 10 | 0 | 10 |
| OGFRL1 | KIAA2026 | 0.717354 | 4 | 0 | 4 |
| OGFRL1 | LRRK2 | 0.716851 | 8 | 0 | 8 |
| OGFRL1 | SCEL | 0.716111 | 9 | 0 | 9 |
| OGFRL1 | CNOT6L | 0.715356 | 5 | 0 | 5 |
| OGFRL1 | FUCA1 | 0.711575 | 6 | 0 | 6 |
For details and further investigation, click here
