Full name: disrupted in renal carcinoma 3 | Alias Symbol: FLJ14199 | ||
Type: non-coding RNA | Cytoband: 2q35 | ||
Entrez ID: 729582 | HGNC ID: HGNC:17805 | Ensembl Gene: ENSG00000231672 | OMIM ID: 608262 |
Drug and gene relationship at DGIdb |
Expression of DIRC3:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | DIRC3 | 729582 | 232434_at | -0.4163 | 0.1942 | |
GSE26886 | DIRC3 | 729582 | 232434_at | 0.0643 | 0.8298 | |
GSE45670 | DIRC3 | 729582 | 232434_at | 0.0844 | 0.6730 | |
GSE63941 | DIRC3 | 729582 | 232434_at | -1.3855 | 0.0206 | |
GSE77861 | DIRC3 | 729582 | 232434_at | -0.1273 | 0.3547 | |
SRP064894 | DIRC3 | 729582 | RNAseq | 0.4685 | 0.2470 | |
SRP133303 | DIRC3 | 729582 | RNAseq | 0.8212 | 0.0739 | |
TCGA | DIRC3 | 729582 | RNAseq | -0.8446 | 0.0222 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DIRC3 expression:
Note: Click image to view full size file.
Copy number change of DIRC3:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | DIRC3 | 729582 | 1 | 13 | 16 | |
GSE20123 | DIRC3 | 729582 | 1 | 13 | 16 | |
GSE43470 | DIRC3 | 729582 | 1 | 7 | 35 | |
GSE46452 | DIRC3 | 729582 | 0 | 5 | 54 | |
GSE47630 | DIRC3 | 729582 | 4 | 5 | 31 | |
GSE54993 | DIRC3 | 729582 | 0 | 3 | 67 | |
GSE54994 | DIRC3 | 729582 | 9 | 9 | 35 | |
GSE60625 | DIRC3 | 729582 | 0 | 3 | 8 | |
GSE74703 | DIRC3 | 729582 | 1 | 5 | 30 | |
GSE74704 | DIRC3 | 729582 | 1 | 7 | 12 | |
TCGA | DIRC3 | 729582 | 11 | 27 | 58 |
Total number of gains: 29; Total number of losses: 97; Total Number of normals: 362.
Somatic mutations of DIRC3:
Generating mutation plots.
Highly correlated genes for DIRC3:
Showing top 20/24 corelated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
DIRC3 | MAML2 | 0.693413 | 3 | 0 | 3 |
DIRC3 | GSG1 | 0.674444 | 3 | 0 | 3 |
DIRC3 | ADAMTSL1 | 0.654348 | 3 | 0 | 3 |
DIRC3 | F10 | 0.654255 | 3 | 0 | 3 |
DIRC3 | PGM5-AS1 | 0.643274 | 3 | 0 | 3 |
DIRC3 | TMEM132B | 0.637447 | 3 | 0 | 3 |
DIRC3 | CECR9 | 0.631608 | 3 | 0 | 3 |
DIRC3 | IL6 | 0.61134 | 4 | 0 | 3 |
DIRC3 | ADH1B | 0.593126 | 3 | 0 | 3 |
DIRC3 | FAM110B | 0.588803 | 3 | 0 | 3 |
DIRC3 | NPR2 | 0.585353 | 3 | 0 | 3 |
DIRC3 | ZNF536 | 0.584915 | 3 | 0 | 3 |
DIRC3 | SYNGR1 | 0.578639 | 3 | 0 | 3 |
DIRC3 | DNALI1 | 0.576148 | 3 | 0 | 3 |
DIRC3 | RPS8 | 0.571422 | 3 | 0 | 3 |
DIRC3 | SCUBE3 | 0.570981 | 4 | 0 | 4 |
DIRC3 | ARMC2 | 0.570133 | 3 | 0 | 3 |
DIRC3 | KCNE1 | 0.569554 | 4 | 0 | 3 |
DIRC3 | RGN | 0.568582 | 3 | 0 | 3 |
DIRC3 | ADCY5 | 0.561259 | 3 | 0 | 3 |
For details and further investigation, click here