DIRC3

 

Full name: disrupted in renal carcinoma 3 Alias Symbol: FLJ14199
Type: non-coding RNA Cytoband: 2q35
Entrez ID: 729582 HGNC ID: HGNC:17805 Ensembl Gene: ENSG00000231672 OMIM ID: 608262
Drug and gene relationship at DGIdb

 

Expression of DIRC3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DIRC3 729582 232434_at -0.4163 0.1942
GSE26886 DIRC3 729582 232434_at 0.0643 0.8298
GSE45670 DIRC3 729582 232434_at 0.0844 0.6730
GSE63941 DIRC3 729582 232434_at -1.3855 0.0206
GSE77861 DIRC3 729582 232434_at -0.1273 0.3547
SRP064894 DIRC3 729582 RNAseq 0.4685 0.2470
SRP133303 DIRC3 729582 RNAseq 0.8212 0.0739
TCGA DIRC3 729582 RNAseq -0.8446 0.0222

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by DIRC3 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of DIRC3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DIRC3 729582 1 13 16
GSE20123 DIRC3 729582 1 13 16
GSE43470 DIRC3 729582 1 7 35
GSE46452 DIRC3 729582 0 5 54
GSE47630 DIRC3 729582 4 5 31
GSE54993 DIRC3 729582 0 3 67
GSE54994 DIRC3 729582 9 9 35
GSE60625 DIRC3 729582 0 3 8
GSE74703 DIRC3 729582 1 5 30
GSE74704 DIRC3 729582 1 7 12
TCGA DIRC3 729582 11 27 58

Total number of gains: 29; Total number of losses: 97; Total Number of normals: 362.  


 

Somatic mutations of DIRC3:

 

Generating mutation plots.

 

Highly correlated genes for DIRC3:

 

Showing top 20/24 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DIRC3MAML20.693413303
DIRC3GSG10.674444303
DIRC3ADAMTSL10.654348303
DIRC3F100.654255303
DIRC3PGM5-AS10.643274303
DIRC3TMEM132B0.637447303
DIRC3CECR90.631608303
DIRC3IL60.61134403
DIRC3ADH1B0.593126303
DIRC3FAM110B0.588803303
DIRC3NPR20.585353303
DIRC3ZNF5360.584915303
DIRC3SYNGR10.578639303
DIRC3DNALI10.576148303
DIRC3RPS80.571422303
DIRC3SCUBE30.570981404
DIRC3ARMC20.570133303
DIRC3KCNE10.569554403
DIRC3RGN0.568582303
DIRC3ADCY50.561259303

For details and further investigation, click here