| Full name: zinc finger protein 536 | Alias Symbol: KIAA0390 | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 9745 | HGNC ID: HGNC:29025 | Ensembl Gene: ENSG00000198597 | OMIM ID: 618037 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF536:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF536 | 9745 | 206403_at | -1.5898 | 0.0102 | |
| GSE20347 | ZNF536 | 9745 | 206403_at | -0.0496 | 0.5933 | |
| GSE23400 | ZNF536 | 9745 | 206403_at | -0.3235 | 0.0000 | |
| GSE26886 | ZNF536 | 9745 | 206403_at | -0.0953 | 0.5020 | |
| GSE29001 | ZNF536 | 9745 | 206403_at | -0.0875 | 0.7748 | |
| GSE38129 | ZNF536 | 9745 | 206403_at | -0.3652 | 0.0004 | |
| GSE45670 | ZNF536 | 9745 | 206403_at | -1.4410 | 0.0000 | |
| GSE53622 | ZNF536 | 9745 | 15081 | -4.1498 | 0.0000 | |
| GSE53624 | ZNF536 | 9745 | 15081 | -3.6989 | 0.0000 | |
| GSE63941 | ZNF536 | 9745 | 206403_at | -2.3280 | 0.0000 | |
| GSE77861 | ZNF536 | 9745 | 206403_at | -0.0843 | 0.5307 | |
| SRP064894 | ZNF536 | 9745 | RNAseq | -3.1538 | 0.0000 | |
| SRP133303 | ZNF536 | 9745 | RNAseq | -2.6698 | 0.0001 | |
| SRP159526 | ZNF536 | 9745 | RNAseq | -2.1744 | 0.0008 | |
| SRP219564 | ZNF536 | 9745 | RNAseq | -1.9185 | 0.1248 | |
| TCGA | ZNF536 | 9745 | RNAseq | -2.2334 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by ZNF536 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF536:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF536 | 9745 | 7 | 7 | 16 | |
| GSE20123 | ZNF536 | 9745 | 7 | 6 | 17 | |
| GSE43470 | ZNF536 | 9745 | 6 | 6 | 31 | |
| GSE46452 | ZNF536 | 9745 | 47 | 1 | 11 | |
| GSE47630 | ZNF536 | 9745 | 8 | 6 | 26 | |
| GSE54993 | ZNF536 | 9745 | 17 | 3 | 50 | |
| GSE54994 | ZNF536 | 9745 | 7 | 11 | 35 | |
| GSE60625 | ZNF536 | 9745 | 9 | 0 | 2 | |
| GSE74703 | ZNF536 | 9745 | 6 | 4 | 26 | |
| GSE74704 | ZNF536 | 9745 | 6 | 4 | 10 | |
| TCGA | ZNF536 | 9745 | 19 | 13 | 64 |
Total number of gains: 139; Total number of losses: 61; Total Number of normals: 288.
Somatic mutations of ZNF536:
Generating mutation plots.
Highly correlated genes for ZNF536:
Showing top 20/1137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF536 | NEGR1 | 0.809052 | 6 | 0 | 6 |
| ZNF536 | PTCHD1 | 0.803267 | 4 | 0 | 4 |
| ZNF536 | LINC01082 | 0.790884 | 6 | 0 | 5 |
| ZNF536 | RSPO2 | 0.789827 | 3 | 0 | 3 |
| ZNF536 | SH3BGRL2 | 0.773745 | 4 | 0 | 4 |
| ZNF536 | FENDRR | 0.769524 | 5 | 0 | 5 |
| ZNF536 | PGM5-AS1 | 0.768713 | 4 | 0 | 4 |
| ZNF536 | ASPA | 0.768019 | 8 | 0 | 7 |
| ZNF536 | FIBIN | 0.762099 | 3 | 0 | 3 |
| ZNF536 | RGS7BP | 0.760754 | 5 | 0 | 5 |
| ZNF536 | NFIA | 0.757359 | 4 | 0 | 4 |
| ZNF536 | PTN | 0.755898 | 3 | 0 | 3 |
| ZNF536 | ZBTB47 | 0.751008 | 3 | 0 | 3 |
| ZNF536 | CTTNBP2 | 0.749251 | 5 | 0 | 5 |
| ZNF536 | PAQR8 | 0.748334 | 4 | 0 | 4 |
| ZNF536 | EDN3 | 0.746456 | 4 | 0 | 4 |
| ZNF536 | TBX5-AS1 | 0.74548 | 3 | 0 | 3 |
| ZNF536 | ANGPTL1 | 0.744013 | 6 | 0 | 5 |
| ZNF536 | C1QTNF7 | 0.743769 | 6 | 0 | 6 |
| ZNF536 | ADCY5 | 0.737359 | 6 | 0 | 6 |
For details and further investigation, click here
