| Full name: forkhead box E1 | Alias Symbol: TTF-2|HFKH4 | ||
| Type: protein-coding gene | Cytoband: 9q22.33 | ||
| Entrez ID: 2304 | HGNC ID: HGNC:3806 | Ensembl Gene: ENSG00000178919 | OMIM ID: 602617 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXE1 | 2304 | 206912_at | 1.5863 | 0.2088 | |
| GSE20347 | FOXE1 | 2304 | 206912_at | 1.2252 | 0.0144 | |
| GSE23400 | FOXE1 | 2304 | 206912_at | 1.1611 | 0.0000 | |
| GSE26886 | FOXE1 | 2304 | 206912_at | 1.1327 | 0.0209 | |
| GSE29001 | FOXE1 | 2304 | 206912_at | 1.2052 | 0.0196 | |
| GSE38129 | FOXE1 | 2304 | 206912_at | 1.5597 | 0.0025 | |
| GSE45670 | FOXE1 | 2304 | 206912_at | 2.2601 | 0.0000 | |
| GSE53622 | FOXE1 | 2304 | 4151 | 1.5181 | 0.0000 | |
| GSE53624 | FOXE1 | 2304 | 4151 | 1.2252 | 0.0000 | |
| GSE63941 | FOXE1 | 2304 | 206912_at | 4.1818 | 0.0122 | |
| GSE77861 | FOXE1 | 2304 | 206912_at | 1.9847 | 0.0060 | |
| GSE97050 | FOXE1 | 2304 | A_33_P3226357 | 1.6144 | 0.0903 | |
| SRP007169 | FOXE1 | 2304 | RNAseq | 3.4177 | 0.0000 | |
| SRP008496 | FOXE1 | 2304 | RNAseq | 3.0897 | 0.0000 | |
| SRP064894 | FOXE1 | 2304 | RNAseq | 1.5912 | 0.0024 | |
| SRP133303 | FOXE1 | 2304 | RNAseq | 1.4599 | 0.0002 | |
| SRP159526 | FOXE1 | 2304 | RNAseq | 2.2504 | 0.0000 | |
| SRP219564 | FOXE1 | 2304 | RNAseq | 0.1022 | 0.9259 | |
| TCGA | FOXE1 | 2304 | RNAseq | 1.6184 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by FOXE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXE1 | 2304 | 7 | 8 | 15 | |
| GSE20123 | FOXE1 | 2304 | 7 | 7 | 16 | |
| GSE43470 | FOXE1 | 2304 | 6 | 3 | 34 | |
| GSE46452 | FOXE1 | 2304 | 6 | 14 | 39 | |
| GSE47630 | FOXE1 | 2304 | 1 | 17 | 22 | |
| GSE54993 | FOXE1 | 2304 | 3 | 3 | 64 | |
| GSE54994 | FOXE1 | 2304 | 8 | 11 | 34 | |
| GSE60625 | FOXE1 | 2304 | 0 | 0 | 11 | |
| GSE74703 | FOXE1 | 2304 | 5 | 3 | 28 | |
| GSE74704 | FOXE1 | 2304 | 3 | 5 | 12 | |
| TCGA | FOXE1 | 2304 | 27 | 22 | 47 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of FOXE1:
Generating mutation plots.
Highly correlated genes for FOXE1:
Showing top 20/902 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXE1 | LRIF1 | 0.728742 | 3 | 0 | 3 |
| FOXE1 | TRAF4 | 0.702075 | 4 | 0 | 4 |
| FOXE1 | HAS3 | 0.681105 | 7 | 0 | 6 |
| FOXE1 | SLC7A11 | 0.68035 | 10 | 0 | 9 |
| FOXE1 | ABCA13 | 0.677348 | 7 | 0 | 5 |
| FOXE1 | DLX5 | 0.675971 | 12 | 0 | 11 |
| FOXE1 | TP63 | 0.67452 | 12 | 0 | 10 |
| FOXE1 | KRT17 | 0.671408 | 3 | 0 | 3 |
| FOXE1 | PRPF4 | 0.670203 | 13 | 0 | 11 |
| FOXE1 | CDCA2 | 0.670182 | 5 | 0 | 4 |
| FOXE1 | B4GALT4 | 0.670034 | 11 | 0 | 10 |
| FOXE1 | COMMD2 | 0.66697 | 4 | 0 | 4 |
| FOXE1 | NFE2L3 | 0.662024 | 5 | 0 | 4 |
| FOXE1 | TRAF7 | 0.659927 | 4 | 0 | 4 |
| FOXE1 | ACTR3 | 0.659547 | 4 | 0 | 4 |
| FOXE1 | IAH1 | 0.657958 | 3 | 0 | 3 |
| FOXE1 | CCDC117 | 0.657341 | 4 | 0 | 3 |
| FOXE1 | PIGW | 0.656023 | 6 | 0 | 4 |
| FOXE1 | FAM220A | 0.651465 | 5 | 0 | 5 |
| FOXE1 | ABCC5 | 0.651387 | 13 | 0 | 12 |
For details and further investigation, click here
