| Full name: hypoxanthine phosphoribosyltransferase 1 | Alias Symbol: HGPRT | ||
| Type: protein-coding gene | Cytoband: Xq26.2-q26.3 | ||
| Entrez ID: 3251 | HGNC ID: HGNC:5157 | Ensembl Gene: ENSG00000165704 | OMIM ID: 308000 |
| Drug and gene relationship at DGIdb | |||
Expression of HPRT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HPRT1 | 3251 | 202854_at | 0.5337 | 0.1901 | |
| GSE20347 | HPRT1 | 3251 | 202854_at | 0.8001 | 0.0001 | |
| GSE23400 | HPRT1 | 3251 | 202854_at | 1.3195 | 0.0000 | |
| GSE26886 | HPRT1 | 3251 | 202854_at | 1.0124 | 0.0000 | |
| GSE29001 | HPRT1 | 3251 | 202854_at | 0.7888 | 0.0154 | |
| GSE38129 | HPRT1 | 3251 | 202854_at | 1.2187 | 0.0000 | |
| GSE45670 | HPRT1 | 3251 | 202854_at | 0.9076 | 0.0001 | |
| GSE53622 | HPRT1 | 3251 | 3152 | 0.8790 | 0.0000 | |
| GSE53624 | HPRT1 | 3251 | 85533 | 1.1080 | 0.0000 | |
| GSE63941 | HPRT1 | 3251 | 202854_at | 1.4821 | 0.0008 | |
| GSE77861 | HPRT1 | 3251 | 202854_at | 0.7191 | 0.0993 | |
| GSE97050 | HPRT1 | 3251 | A_23_P11372 | 0.8287 | 0.1186 | |
| SRP007169 | HPRT1 | 3251 | RNAseq | 1.1406 | 0.0007 | |
| SRP008496 | HPRT1 | 3251 | RNAseq | 1.1749 | 0.0000 | |
| SRP064894 | HPRT1 | 3251 | RNAseq | 1.0333 | 0.0000 | |
| SRP133303 | HPRT1 | 3251 | RNAseq | 1.5481 | 0.0000 | |
| SRP159526 | HPRT1 | 3251 | RNAseq | 0.8113 | 0.0036 | |
| SRP193095 | HPRT1 | 3251 | RNAseq | 0.3324 | 0.0714 | |
| SRP219564 | HPRT1 | 3251 | RNAseq | 0.9993 | 0.0208 | |
| TCGA | HPRT1 | 3251 | RNAseq | 0.2466 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by HPRT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HPRT1:
No record found for this gene.
Somatic mutations of HPRT1:
Generating mutation plots.
Highly correlated genes for HPRT1:
Showing top 20/1979 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HPRT1 | GTF2H3 | 0.780659 | 3 | 0 | 3 |
| HPRT1 | DNAJB11 | 0.780422 | 5 | 0 | 5 |
| HPRT1 | CDKN3 | 0.77009 | 13 | 0 | 13 |
| HPRT1 | EME1 | 0.767661 | 5 | 0 | 5 |
| HPRT1 | CEP55 | 0.76051 | 12 | 0 | 12 |
| HPRT1 | TRIM47 | 0.754605 | 3 | 0 | 3 |
| HPRT1 | GMNN | 0.754176 | 13 | 0 | 13 |
| HPRT1 | ECT2 | 0.753895 | 11 | 0 | 11 |
| HPRT1 | VRK1 | 0.751187 | 13 | 0 | 13 |
| HPRT1 | TPX2 | 0.750516 | 13 | 0 | 12 |
| HPRT1 | RANBP1 | 0.749739 | 10 | 0 | 10 |
| HPRT1 | XPR1 | 0.747669 | 7 | 0 | 7 |
| HPRT1 | DMXL2 | 0.747287 | 4 | 0 | 4 |
| HPRT1 | PAICS | 0.742121 | 12 | 0 | 12 |
| HPRT1 | CENPI | 0.739798 | 12 | 0 | 12 |
| HPRT1 | ACLY | 0.739402 | 11 | 0 | 10 |
| HPRT1 | MCM6 | 0.739228 | 13 | 0 | 12 |
| HPRT1 | WDR66 | 0.738991 | 8 | 0 | 8 |
| HPRT1 | GINS1 | 0.738151 | 12 | 0 | 12 |
| HPRT1 | ADO | 0.735625 | 4 | 0 | 4 |
For details and further investigation, click here
