| Full name: heat shock protein family H (Hsp110) member 1 | Alias Symbol: HSP105B|KIAA0201|HSP105A|NY-CO-25 | ||
| Type: protein-coding gene | Cytoband: 13q12.3 | ||
| Entrez ID: 10808 | HGNC ID: HGNC:16969 | Ensembl Gene: ENSG00000120694 | OMIM ID: 610703 |
| Drug and gene relationship at DGIdb | |||
Expression of HSPH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPH1 | 10808 | 206976_s_at | 1.0048 | 0.0981 | |
| GSE20347 | HSPH1 | 10808 | 206976_s_at | 1.0712 | 0.0001 | |
| GSE23400 | HSPH1 | 10808 | 206976_s_at | 1.3232 | 0.0000 | |
| GSE26886 | HSPH1 | 10808 | 206976_s_at | 0.5359 | 0.0662 | |
| GSE29001 | HSPH1 | 10808 | 206976_s_at | 1.1020 | 0.0069 | |
| GSE38129 | HSPH1 | 10808 | 206976_s_at | 1.2378 | 0.0000 | |
| GSE45670 | HSPH1 | 10808 | 206976_s_at | 1.4333 | 0.0002 | |
| GSE53622 | HSPH1 | 10808 | 3350 | 1.1413 | 0.0000 | |
| GSE53624 | HSPH1 | 10808 | 3350 | 1.3603 | 0.0000 | |
| GSE63941 | HSPH1 | 10808 | 206976_s_at | 0.1924 | 0.7989 | |
| GSE77861 | HSPH1 | 10808 | 206976_s_at | 1.2372 | 0.0016 | |
| GSE97050 | HSPH1 | 10808 | A_23_P88119 | 0.2164 | 0.4543 | |
| SRP007169 | HSPH1 | 10808 | RNAseq | -0.6967 | 0.3184 | |
| SRP008496 | HSPH1 | 10808 | RNAseq | -0.1250 | 0.7849 | |
| SRP064894 | HSPH1 | 10808 | RNAseq | 1.3927 | 0.0000 | |
| SRP133303 | HSPH1 | 10808 | RNAseq | 1.4070 | 0.0000 | |
| SRP159526 | HSPH1 | 10808 | RNAseq | 1.2190 | 0.0082 | |
| SRP193095 | HSPH1 | 10808 | RNAseq | 0.7781 | 0.0001 | |
| SRP219564 | HSPH1 | 10808 | RNAseq | -0.2735 | 0.7398 | |
| TCGA | HSPH1 | 10808 | RNAseq | 0.1927 | 0.0009 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by HSPH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPH1 | 10808 | 1 | 14 | 15 | |
| GSE20123 | HSPH1 | 10808 | 1 | 13 | 16 | |
| GSE43470 | HSPH1 | 10808 | 2 | 12 | 29 | |
| GSE46452 | HSPH1 | 10808 | 0 | 33 | 26 | |
| GSE47630 | HSPH1 | 10808 | 2 | 27 | 11 | |
| GSE54993 | HSPH1 | 10808 | 12 | 2 | 56 | |
| GSE54994 | HSPH1 | 10808 | 2 | 15 | 36 | |
| GSE60625 | HSPH1 | 10808 | 0 | 3 | 8 | |
| GSE74703 | HSPH1 | 10808 | 2 | 9 | 25 | |
| GSE74704 | HSPH1 | 10808 | 0 | 11 | 9 | |
| TCGA | HSPH1 | 10808 | 8 | 37 | 51 |
Total number of gains: 30; Total number of losses: 176; Total Number of normals: 282.
Somatic mutations of HSPH1:
Generating mutation plots.
Highly correlated genes for HSPH1:
Showing top 20/1741 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPH1 | SERPINH1 | 0.758781 | 9 | 0 | 9 |
| HSPH1 | RHOQ | 0.747356 | 3 | 0 | 3 |
| HSPH1 | YWHAG | 0.733718 | 6 | 0 | 5 |
| HSPH1 | HSP90AA1 | 0.729793 | 12 | 0 | 11 |
| HSPH1 | XPR1 | 0.726063 | 6 | 0 | 6 |
| HSPH1 | CKS1B | 0.721202 | 10 | 0 | 10 |
| HSPH1 | COL6A2 | 0.720571 | 4 | 0 | 4 |
| HSPH1 | BCL9L | 0.719979 | 3 | 0 | 3 |
| HSPH1 | FADS1 | 0.717984 | 3 | 0 | 3 |
| HSPH1 | KIF14 | 0.71791 | 9 | 0 | 9 |
| HSPH1 | FMNL2 | 0.712827 | 7 | 0 | 7 |
| HSPH1 | EPPK1 | 0.71262 | 6 | 0 | 6 |
| HSPH1 | FBLIM1 | 0.711414 | 7 | 0 | 6 |
| HSPH1 | ENAH | 0.711314 | 11 | 0 | 10 |
| HSPH1 | GATAD2B | 0.710395 | 3 | 0 | 3 |
| HSPH1 | LAMC2 | 0.709683 | 10 | 0 | 9 |
| HSPH1 | NEDD1 | 0.707084 | 7 | 0 | 7 |
| HSPH1 | LAPTM4B | 0.706228 | 11 | 0 | 11 |
| HSPH1 | SLC25A32 | 0.705191 | 11 | 0 | 11 |
| HSPH1 | HSPD1 | 0.703763 | 12 | 0 | 10 |
For details and further investigation, click here
