| Full name: DnaJ heat shock protein family (Hsp40) member B2 | Alias Symbol: HSPF3|CMT2T | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 3300 | HGNC ID: HGNC:5228 | Ensembl Gene: ENSG00000135924 | OMIM ID: 604139 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB2 | 3300 | 202500_at | 0.0685 | 0.8995 | |
| GSE20347 | DNAJB2 | 3300 | 202500_at | -0.2654 | 0.1074 | |
| GSE23400 | DNAJB2 | 3300 | 202500_at | 0.0654 | 0.4236 | |
| GSE26886 | DNAJB2 | 3300 | 202500_at | -0.7050 | 0.0044 | |
| GSE29001 | DNAJB2 | 3300 | 202500_at | -0.0779 | 0.8542 | |
| GSE38129 | DNAJB2 | 3300 | 202500_at | -0.2862 | 0.0170 | |
| GSE45670 | DNAJB2 | 3300 | 202500_at | 0.4239 | 0.0298 | |
| GSE53622 | DNAJB2 | 3300 | 36637 | -0.3532 | 0.0000 | |
| GSE53624 | DNAJB2 | 3300 | 36637 | -0.3414 | 0.0000 | |
| GSE63941 | DNAJB2 | 3300 | 202500_at | -0.5800 | 0.1535 | |
| GSE77861 | DNAJB2 | 3300 | 202500_at | 0.2742 | 0.4054 | |
| GSE97050 | DNAJB2 | 3300 | A_24_P102981 | -0.1480 | 0.4638 | |
| SRP007169 | DNAJB2 | 3300 | RNAseq | -0.8924 | 0.0287 | |
| SRP008496 | DNAJB2 | 3300 | RNAseq | -0.5730 | 0.0511 | |
| SRP064894 | DNAJB2 | 3300 | RNAseq | 0.4183 | 0.1701 | |
| SRP133303 | DNAJB2 | 3300 | RNAseq | 0.0996 | 0.6480 | |
| SRP159526 | DNAJB2 | 3300 | RNAseq | -0.0788 | 0.7251 | |
| SRP193095 | DNAJB2 | 3300 | RNAseq | -0.2582 | 0.0460 | |
| SRP219564 | DNAJB2 | 3300 | RNAseq | -0.1716 | 0.5261 | |
| TCGA | DNAJB2 | 3300 | RNAseq | -0.0693 | 0.2138 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB2 | 3300 | 2 | 14 | 14 | |
| GSE20123 | DNAJB2 | 3300 | 2 | 13 | 15 | |
| GSE43470 | DNAJB2 | 3300 | 1 | 6 | 36 | |
| GSE46452 | DNAJB2 | 3300 | 0 | 5 | 54 | |
| GSE47630 | DNAJB2 | 3300 | 4 | 5 | 31 | |
| GSE54993 | DNAJB2 | 3300 | 1 | 2 | 67 | |
| GSE54994 | DNAJB2 | 3300 | 8 | 9 | 36 | |
| GSE60625 | DNAJB2 | 3300 | 0 | 3 | 8 | |
| GSE74703 | DNAJB2 | 3300 | 1 | 5 | 30 | |
| GSE74704 | DNAJB2 | 3300 | 2 | 7 | 11 | |
| TCGA | DNAJB2 | 3300 | 12 | 26 | 58 |
Total number of gains: 33; Total number of losses: 95; Total Number of normals: 360.
Somatic mutations of DNAJB2:
Generating mutation plots.
Highly correlated genes for DNAJB2:
Showing top 20/72 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB2 | FBXO25 | 0.697892 | 3 | 0 | 3 |
| DNAJB2 | ING5 | 0.677119 | 3 | 0 | 3 |
| DNAJB2 | COPG1 | 0.672111 | 3 | 0 | 3 |
| DNAJB2 | AP1M1 | 0.665404 | 3 | 0 | 3 |
| DNAJB2 | ATG9A | 0.661834 | 12 | 0 | 11 |
| DNAJB2 | NRG4 | 0.643677 | 3 | 0 | 3 |
| DNAJB2 | NUDT16L1 | 0.629006 | 5 | 0 | 4 |
| DNAJB2 | P2RY1 | 0.623375 | 3 | 0 | 3 |
| DNAJB2 | BAZ2A | 0.622492 | 5 | 0 | 4 |
| DNAJB2 | GID8 | 0.612652 | 3 | 0 | 3 |
| DNAJB2 | NICN1 | 0.611189 | 3 | 0 | 3 |
| DNAJB2 | MEGF8 | 0.609689 | 3 | 0 | 3 |
| DNAJB2 | SMG5 | 0.607596 | 4 | 0 | 3 |
| DNAJB2 | CNPPD1 | 0.606989 | 5 | 0 | 5 |
| DNAJB2 | NEUROG1 | 0.600818 | 4 | 0 | 3 |
| DNAJB2 | ZFAND2B | 0.598517 | 5 | 0 | 5 |
| DNAJB2 | TUSC2 | 0.597015 | 4 | 0 | 3 |
| DNAJB2 | TUBA4A | 0.590232 | 8 | 0 | 5 |
| DNAJB2 | PAFAH2 | 0.587109 | 4 | 0 | 3 |
| DNAJB2 | ACTR10 | 0.585829 | 4 | 0 | 3 |
For details and further investigation, click here
