COPG1

 

Full name: coatomer protein complex subunit gamma 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 3q21.3
Entrez ID: 22820 HGNC ID: HGNC:2236 Ensembl Gene: ENSG00000181789 OMIM ID: 615525
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of COPG1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 COPG1 22820 217749_at 0.6855 0.1281
GSE20347 COPG1 22820 217749_at 0.0868 0.5965
GSE23400 COPG1 22820 217749_at 0.4767 0.0000
GSE26886 COPG1 22820 217749_at -0.0975 0.5684
GSE29001 COPG1 22820 217749_at 0.1140 0.7807
GSE38129 COPG1 22820 217749_at 0.4882 0.0202
GSE45670 COPG1 22820 217749_at 0.5015 0.0064
GSE53622 COPG1 22820 144005 0.3724 0.0000
GSE53624 COPG1 22820 144005 0.3903 0.0000
GSE63941 COPG1 22820 217749_at -0.8504 0.0276
GSE77861 COPG1 22820 217749_at 0.1193 0.7183
SRP007169 COPG1 22820 RNAseq 0.6742 0.1339
SRP008496 COPG1 22820 RNAseq 0.4472 0.0853
SRP064894 COPG1 22820 RNAseq 0.7815 0.0000
SRP133303 COPG1 22820 RNAseq 0.5035 0.0004
SRP159526 COPG1 22820 RNAseq 0.3369 0.0646
SRP193095 COPG1 22820 RNAseq 0.1184 0.4178
SRP219564 COPG1 22820 RNAseq 0.6821 0.0138

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by COPG1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of COPG1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 COPG1 22820 17 0 13
GSE20123 COPG1 22820 17 0 13
GSE43470 COPG1 22820 19 0 24
GSE46452 COPG1 22820 14 5 40
GSE47630 COPG1 22820 18 3 19
GSE54993 COPG1 22820 2 8 60
GSE54994 COPG1 22820 32 3 18
GSE60625 COPG1 22820 0 6 5
GSE74703 COPG1 22820 17 0 19
GSE74704 COPG1 22820 13 0 7
TCGA COPG1 22820 58 5 33

Total number of gains: 207; Total number of losses: 30; Total Number of normals: 251.  

 

Somatic mutations of COPG1:

 

Generating mutation plots.

 

Highly correlated genes for COPG1:

 

Showing top 20/196 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
COPG1KPNA20.733643303
COPG1COPB20.679081807
COPG1U2SURP0.676804303
COPG1DNAJB20.672111303
COPG1TMEM2230.667409303
COPG1FOXM10.658001505
COPG1RPN10.6437531109
COPG1UHRF10.639131403
COPG1NOL110.636216403
COPG1TOPBP10.633916605
COPG1CCNJ0.632843404
COPG1TFG0.632657806
COPG1MTBP0.632176403
COPG1ECT20.623127504
COPG1WDR530.61323403
COPG1NACC10.612731303
COPG1MRPS120.609558504
COPG1TSR30.607569404
COPG1ACTL6A0.606669504
COPG1SEC61A10.6040121107

For details and further investigation, click here